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Albuminuria

Renal & ElectrolyteLab test / biomarkerriskpartially modifiable
45
evidence score

Also known as: Increased urinary albumin excretion / albuminuria, increased urinary albumin excretion, microalbuminuria, proteinuria, uacr, urinary albumin

PREVENT status

✓ Used by PREVENT (optional input).

Causal support

trial evidence

Score components
lit volume: 20meta-analyses: 11.6trials: 13.4genetic: 0MR bonus:

References (99)

3 meta-analyses / systematic reviews

Clinical trials (21)

NCTTitleStatusTypeInterventions
NCT07175051Targeting the Pathophysiology of Sickle Cell-Related Kidney Disease Using the SGLT2 Inhibitors, EmpagliflozinRECRUITINGINTERVENTIONALEmpagliflozin (oral)
NCT07588256New Taipei City 888 Digital Medical AI Platform for the Prevention and Treatment of the Three Highs (Hypertension, Hyperglycemia, Hyperlipidemia) and Cardio-Renal-Vascular Diseases: Validation and Implementation Through Large-Scale Cluster Randomized Clinical Trials: T-888-DIGICARE-DREAMRECRUITINGINTERVENTIONALInteractive digital modules, Antihypertensive Medication Management
NCT07204743Efficacy and Safety of Dapagliflozin in Children With ProteinuriaACTIVE NOT RECRUITINGINTERVENTIONALDapagliflozin (5-10 mg daily) - SGLT2 Inhibitor Therapy
NCT05874141Comorbidities in Type 2 Diabetes Mellitus: An Observational Study in Kharga City, New Valley Governate, EgyptCOMPLETEDINTERVENTIONALHBA1C, Lipid profile, including total, LDL, and HDL cholesterol and Triglycerides, Urine analysis and urinary albumin-to-creatinine ratio
NCT05283057Effect of Sodium Glucose Transporter 2 Inhibitor Empagliflozin on Proteinuria and Kidney Disease Progression in Patients With Non-diabetic Glomerulonephritis- A Randomized Controlled TrialCOMPLETEDINTERVENTIONALEmpagliflozin 25 MG, placebo
NCT04127084Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetes: a Prospective Interventional StudyUNKNOWNINTERVENTIONALSGLT2 Inhibition
NCT04073927The Butyful Study. Effect of Butyrate on Inflammation and Albuminuria in Patients With Albuminuria, Type 1 Diabetes and Intestinal Inflammation A Randomized, Double-blind, Placebo-controlled StudyUNKNOWNINTERVENTIONALSodium butyrate
NCT03190694A Study to Assess the Renoprotective Effects of the SGLT2 Inhibitor Dapagliflozin in Non-Diabetic Patients With Proteinuria: a Randomized Double Blind 6-Weeks Cross-Over TrialCOMPLETEDINTERVENTIONALDapagliflozin 10mg
NCT03089333Effects of Dapagliflozin, an SGLT2 Inhibitor, on Hemodynamic Parameters, Target Organ Damage and Obesity Profile in Resistant Hypertensive SubjectsCOMPLETEDINTERVENTIONALDapagliflozin 10mg, Glibenclamide 5Mg Tablet
NCT02442921The Effect of Colchicine Treatment on the Progression of Proteinuria in Patients With Diabetic Nephropathy.UNKNOWNINTERVENTIONALColchicine, Placebo
NCT01989754A Randomized, Multicenter, Double-Blind, Parallel, Placebo-Controlled Study of the Effects of Canagliflozin on Renal Endpoints in Adult Subjects With Type 2 Diabetes MellitusCOMPLETEDINTERVENTIONALPlacebo, Canagliflozin, 100 mg, Canagliflozin, 300 mg
NCT02035891Low-dose Colchicine Intervention in Patients With Type 2 Diabetes Mellitus and Microalbuminuria: Chongqing StudyUNKNOWNINTERVENTIONALcolchicine 0.5mg/d, placebo 0.5mg/d
NCT01588795Renal Denervation in Patients With Diabetic Nephropathy and Persistent ProteinuriaCOMPLETEDINTERVENTIONALPercutaneous renal denervation and TMNS, Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin
NCT01093157A Dose-finding Pilot Study of ACTH (Adrenocorticotropic Hormone) on the Proteinuria and Serum Lipoprotein Profile in Patients With Idiopathic Membranous Nephropathy (MN)COMPLETEDINTERVENTIONALAdrenocorticotrophic hormone ACTH
NCT00805753A Dose-Finding Pilot Study of ACTH on the Serum Lipoprotein Profile and Proteinuria in Patients With Idiopathic Membranous Nephropathy (MN)COMPLETEDINTERVENTIONALACTH
NCT00199927A Prospective, Randomized, Multicenter Trial Testing the Antiproteinuric Effect of Statins Added to Combined ACE-inhibitor and Angiotensin Receptor Antagonist Therapy in Proteinuric, Chronic NephropathiesCOMPLETEDINTERVENTIONALFluvastatin, standard therapy
NCT00741702Diabetes Risk Evaluation and Microalbuminuria in Saskatchewan First Nations PeoplesCOMPLETEDINTERVENTIONALNurse administered treatment algorithm
NCT05881447Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in a Primary Care Setting in Semirural Sub-Saharan AfricaRECRUITINGOBSERVATIONAL
NCT04272359Prospective, Parallel Goups Study, Aimed to Evaluating Possible Benefits of the Treatment of New Generation Hypoglycaemic Drugs Compared to Sulphonylureas for the Tratment of Type 2 Diabetes MellitusUNKNOWNOBSERVATIONALSulfa-zero: possible benefits of the treatment of new generation hypoglycaemic drugs compared to sulphonylureas
NCT02226055An Investigation Into the Cardiovascular Risk and Aetiology of CKDu in Sri LankaCOMPLETEDOBSERVATIONALArterial Stiffness Assessment
NCT00479518Prognostic Value of Cardiac and Renal Markers in the Acute Phase of Ischemic Stroke or Transient Ischemic Attack :Albuminuria-Brain Natriuretic Peptide-Cystatine C in StrokeCOMPLETEDOBSERVATIONAL

Genetic associations (0)

None linked.