De novo evidence atlas
Every risk factor ever reported for atherosclerotic cardiovascular disease, graded by evidence.
A ground-up harvest of the primary literature, clinical trials, and human genetics catalogs 997 distinct risk factors across 15 categories — from lipids and blood pressure to clonal hematopoiesis, air pollution, and gut-microbiome metabolites. Each factor links to its supporting evidence and is scored so you can judge how much weight it carries — and see which the AHA PREVENT equations omit.
997
risk factors cataloged
6,441
articles harvested
5,715
clinical trials linked
6,227
GWAS associations
135
strongly-evidenced (A/B)
114
strong factors PREVENT omits
Risk factors by category
Each bar shows the count of distinct factors; the shaded portion is strongly-evidenced (grade A or B).
Novel & Emerging Biomarkers
15/142
Imaging & Subclinical Disease
7/123
Inflammatory & Immune
15/89
Comorbid Conditions
11/89
Lifestyle & Behavioral
13/86
Genetic & Family History
8/86
Psychosocial & Mental Health
6/54
Environmental & Occupational
9/50
Lipids & Lipoproteins
11/49
Hemostatic & Thrombotic
4/46
Anthropometric & Body Composition
7/44
Blood Pressure & Hemodynamics
7/41
Glycemic & Metabolic
9/37
Demographic & Social
8/37
Renal & Electrolyte
5/24