C
Apolipoprotein A-I
Lipids & LipoproteinsLab test / biomarkerprotectivepartially modifiable
16
evidence score
Also known as: apo a-i, apoa-i, apoa1, apolipoprotein AI
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 11.5meta-analyses: 0trials: 4.8genetic: 0MR bonus:
References (13)
0 meta-analyses / systematic reviews- Dietary, macronutrient, micronutrient, and nutrigenetic factors impacting cardiovascular risk markers apolipoprotein B and apolipoprotein A1: a narrative review. — Nutrition reviews 2024 · PMID 37615981
- Exploring Genetic Associations of 3 Types of Risk Factors With Ischemic Stroke: An Integrated Bioinformatics Study. — Stroke 2024 · PMID 38591222
- MicroRNA-320b Modulates Cholesterol Efflux and Atherosclerosis. — Journal of atherosclerosis and thrombosis 2021 · PMID 33536383
- Apolipoproteins in vascular biology and atherosclerotic disease. — Nature reviews. Cardiology 2021 · PMID 34625741
- Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease. — International journal of epidemiology 2021 · PMID 34999880
- PON1 status and homocysteine levels as potential biomarkers for cardiovascular disease. — Experimental gerontology 2020 · PMID 32827712
- Modified lipoproteins in periodontitis: a link to cardiovascular disease? — Bioscience Reports 2019 · PMID 30842338
- Comparison of Conventional Lipoprotein Tests and Apolipoproteins in the Prediction of Cardiovascular Disease — Circulation 2019 · PMID 31216866
- Apolipoprotein B and apolipopotein A-I in vascular risk prediction - a review. — Current pharmaceutical design 2014 · PMID 24953398
- Major lipids, apolipoproteins, and risk of vascular disease. — JAMA 2009 · PMID 19903920
- Risk Factors for Early Myocardial Infarction in South Asians Compared With Individuals in Other Countries — JAMA 2007 · PMID 17227980
- [Apolipoprotein B and A-I: cardiovascular risk factor?]. — Revista da Associacao Medica Brasileira (1992) 2007 · PMID 17665079
- Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. — Lancet (London, England) · PMID 15364185
Clinical trials (2)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT03473223 | A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects With Acute Coronary Syndrome | COMPLETED | INTERVENTIONAL | Apolipoprotein A-I [human] (apoA-I), Placebo |
| NCT00728910 | Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study | COMPLETED | INTERVENTIONAL | Atorvastatin, ABT335, ER Niacin |
Genetic associations (0)
None linked.