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Atrial fibrillation

Comorbid ConditionsDisease / conditionriskpartially modifiable
58
evidence score
PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 23.4meta-analyses: 20trials: 15genetic: 0MR bonus:

References (219)

16 meta-analyses / systematic reviews

Clinical trials (144)

showing top 60
NCTTitleStatusTypeInterventions
NCT07287345Adjunctive Colchicine's Effect on Inflammatory Markers and Corresponding New-Onset Atrial Fibrillation Rates Post Coronary Artery Bypass Graft Procedure: A Pilot StudyRECRUITINGINTERVENTIONALColchicine (Colcrys®), Placebo
NCT06212674Single-stage Pulmonary Vein Isolation Combined With Percutaneous Left Atrial Appendage Occluder Implantation in Patients With Recent Onset Ischemic Stroke and Atrial Fibrillation (PILOS-AF)RECRUITINGINTERVENTIONALPVI + LAAO, single stage, LAAO, NOAC
NCT06735001Identification of the Metabolic Signature of Atrial Fibrillation for Personalized PreventionRECRUITINGINTERVENTIONALFA ablation, Lab test
NCT07482020A Randomized Controlled Trial of SGLT2 Inhibitors to Improve Left Atrial Function in Patients With Paroxysmal Atrial Fibrillation and Comorbid Hypertension and Abnormal Glucose MetabolismRECRUITINGINTERVENTIONALSGLT-2 inhibitors, Placebo
NCT07614659Uppsala Self-Screening of Cardiovascular Health: A Randomized Controlled Trial of Home-Based Multimodal Cardiovascular Screening Versus Usual Care in Middle-Aged and Older AdultsRECRUITINGINTERVENTIONALHome-based multimodal cardiovascular screening
NCT06005233Smartwatches for Detection of Atrial Fibrillation (AFib) in Secondary Prevention of Cryptogenic Stroke - WATCH AFib A Prospective, Intraindividual-controlled, Multicenter Clinical StudyRECRUITINGINTERVENTIONALSmartwatch
NCT06405750Left Atrial Appendage Arrhythmogenic and Thrombogenic SubstrateRECRUITINGINTERVENTIONALleft atrial appendage closure
NCT06067438A Prospective, Randomized Controlled Trial Evaluating the Efficacy of Amiodarone in the Prevention of Postoperative Atrial Fibrillation in Patients Undergoing Minimally Invasive EsophagectomyRECRUITINGINTERVENTIONALAmiodarone Hydrochloride, Saline
NCT05890664Colchicine After Electrocardioversion for Atrial Fibrillation - The COLECTRO-AF TrialRECRUITINGINTERVENTIONALColchicine, Placebo
NCT06775028AFFIRMO - Atrial Fibrillation Integrated Approach in Frail, Multimorbid and Polymedicated Older PeopleRECRUITINGINTERVENTIONALiABC platform use
NCT05852704SGLT2 Inhibitor TrEatment iN Patients Awaiting cOronary arTery bYpass Surgery to Reduce Post-opErative Atrial Fibrillation and Kidney Injury (STENOTYPE Trial)RECRUITINGINTERVENTIONALDapagliflozin 10mg Tab, Placebo Tab
NCT05978388Coronary Computed Tomography AngioGraphy Prior to Catheter Ablation in Patients With Atrial FIBrillationRECRUITINGINTERVENTIONALAnalysis of coronary CT Angiography and CAC scoring at the time of catheter ablation
NCT07447297Efficacy of Early Rhythm Control Therapy in Patients With Subclinical Atrial FibrillationRECRUITINGINTERVENTIONALearly rhythm control group, cardioversion, catheter ablation, general control
NCT06253000Comparative Analysis of Radiofrequency and Cryoablation of the Posterior Wall of the Left Atrium in Patients With Persistent Atrial FibrillationRECRUITINGINTERVENTIONALCryoablation, Radiofrequency ablation
NCT05369195Cerebral Protection in Transcatheter Left Atrial Appendage Occlusion in Patients With Atrial FibrillationRECRUITINGINTERVENTIONALLAAC procedure with the use of transcatheter cerebral protection system, LAAC procedure without the use of transcatheter cerebral protection system
NCT05367037Physiological Ventricular Pacing Versus Managed Ventricular Pacing for Persistent Atrial Fibrillation Prevention in Patients With Prolonged Atrioventricular Interval: a Multicenter RCTRECRUITINGINTERVENTIONALPhysioVP, DDD-VPA
NCT05565781Impact of Non-invasive Remote Monitoring Via Wearable Technologies for Detection of Atrial Fibrillation in Patients With Cryptogenic StrokeRECRUITINGINTERVENTIONALECG smartwatch, Insertable Cardiac Monitor (ICM), External ECG Monitoring
NCT03710902Empowerment and Mobile Technology in the Control of Cardiovascular Risk Factors in Patients With Ischemic StrokeRECRUITINGINTERVENTIONALECG monitoring for 3 weeks, Self-monitoring of BP and self-titration of antihypertensive medication
NCT07611019Randomized, Double-Blind, Placebo-Controlled Trial of Colchicine to Prevent Post-Operative Atrial Fibrillation After CABG With Strategy-Stratified RandomizationENROLLING BY INVITATIONINTERVENTIONALColchicine 0.5 MG oral tablet twice daily, Placebo Oral Tablet
NCT07598903Pharmacy-based Opportunistic Screening for Atrial Fibrillation Using a Portable ECG Device Integrated With Emergency Medical Services: a Prospective Type-1 Hybrid Implementation Study (NUMAPLUS Project)NOT YET RECRUITINGINTERVENTIONALIntegrated pharmacy-based AF screening circuit
NCT07237308A Multicenter Prospective Randomized Study to Evaluate the Efficacy of Apixaban and Clopidogrel on the Prevention of Recurrent Ischemic Stroke in Patients With Atrial Fibrillation and Cerebral AtherosclerosisNOT YET RECRUITINGINTERVENTIONALApixaban, Clopidogrel
NCT06765356Pragmatic Evaluation of a Pentaspline Pulsed Field Ablation System to Treat Atrial Fibrillation and Related ArrhythmiasACTIVE NOT RECRUITINGINTERVENTIONALFarapulse Catheter System, Low-dose Colchicine
NCT04684212Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AF: The CORRAL-AF StudyWITHDRAWNINTERVENTIONALLAmbre PlusTM Left Atrial Appendage Closure System, Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)
NCT06378021Post Operative Atrial Fibrillation: Alleviation by Calcium Chloride Injection Into Cardiac Ganglionic Plexus During Coronary Artery Bypass Grafting.UNKNOWNINTERVENTIONALCalcium Chloride, Sodium Chloride 0.9% Inj
NCT07399379Implementation of an Augmented Reality System to Complement Discharge Information in Hospitalized Cardiology PatientsCOMPLETEDINTERVENTIONALAugmented reality app
NCT06159985Effect of Left Posterior Pericardiotomy for the Prevention of Postoperative Atrial Fibrillation in Coronary Artery Bypass Grafting: A Prospective Randomized Controlled TrialCOMPLETEDINTERVENTIONALleft posterior pericardiostomy
NCT06058130Combination of Antiplatelet and Anticoagulation for Acute Ischemic Stroke Patients Witn Concomitant Non-valvular Atrial Fibrillation and Extracranial/Intracranial Artery StenosisUNKNOWNINTERVENTIONALAnticoagulant Oral, Anticoagulation combined with antiplatelet therapy
NCT05993897Effect of Sodium Glucose Co-transporter 2 Inhibitors on Left Atrium Remodeling in Non-valvular Paroxysmal Atrial Fibrillation PatientsUNKNOWNINTERVENTIONALSodium Glucose Co-transporter 2 (SGLT2) Inhibitor, Rhythm control and anticoagulation
NCT05820295Improving How Older Adults at Risk for Cardiovascular Outcomes Are Selected for Care CoordinationCOMPLETEDINTERVENTIONALCare coordination delivered based on perceived need, Care coordination delivered based on usual care (e.g. discharge from hospital)
NCT04683692A Pilot Randomized Study of the Use of The Sentinel Device for Cerebral Protection During Atrial Fibrillation Ablation: MRI Imaging and Laboratory Sub-studyWITHDRAWNINTERVENTIONALMagnetic Resonance Imaging (MRI), Laboratory Testing
NCT05459974Use of Colchicine to Decrease Atrial Fibrillation Recurrence After Ablation: Randomized Placebo Controlled Trial (Colchicine AF Trial)UNKNOWNINTERVENTIONALColchicine 0.6 mg, Placebo
NCT05084118A Prospective, Randomized, Double- Blind, Placebo- Controlled Study to Evaluate the Efficacy of Landiolol Hydrochloride for Prevention of Atrial Fibrillation in Patients Undergoing Cardiac SurgeryUNKNOWNINTERVENTIONALLandiolol HCl, Placebo
NCT04870424Colchicine for Patients With Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement (Co-STAR): a Randomized-controlled TrialCOMPLETEDINTERVENTIONALColchicine, Placebo
NCT04276155Management of Anticoagulant Therapy Monitored by an Implantable Device With Telecardiology in Patients With Acute Coronary Syndrome Associated With de Novo Atrial Fibrillation Arrhythmia: A Prospective Multicenter StudyACTIVE NOT RECRUITINGINTERVENTIONALnon-systematic prescription of anticoagulant therapy
NCT04479722Safety And EFficacy of Using LEft Atrium APpendage Closure in Nonvalvular AtRial FibrillatiOn PatienTs With High Risk of ischEmiC sTroke -- A Prospective Multicenter Randomized Clinical TrialACTIVE NOT RECRUITINGINTERVENTIONALLeft atrial appendage closure procedure
NCT04624646Clinical Implication of Atrial Fibrillation Detection Using Wearable Device in Patients With Cryptogenic Stroke - The Comparison Between Short-term Continuous Patch and Long-term Discontinuous MonitoringACTIVE NOT RECRUITINGINTERVENTIONALDiscontinuous monitoring, Continuous single-lead ECG Patch, 24-hour Holter monitoring
NCT04160117Impact of Short-course Colchicine Versus Placebo After Pulmonary Vein Isolation (IMPROVE-PVI): A Pilot StudyCOMPLETEDINTERVENTIONALColchicine 0.6 mg, Matching placebo
NCT04224545Colchicine for Prevention Atrial Fibrillation After Cardiac Surgery in the Early Postoperative PeriodCOMPLETEDINTERVENTIONALColchicine Pill, Placebo
NCT04429646A Prospective, Multicenter, Randomized, Active Controlled, Clinical Trial of the LAMax LAA Closure System Compared to the Watchman® LAAC Device for Subjects With Non-valvular Atrial Fibrillation to Reduce the Risk of Ischemic StrokeCOMPLETEDINTERVENTIONALPercutaneous left atrial appendage closure-LAMax, Percutaneous left atrial appendage closure-Watchman
NCT04282993Wearable Devices for Secondary Prevention of Ischemic StrokeUNKNOWNINTERVENTIONALWearable devices for identifying and measuring risk factors for ischemic stroke, Standard of care monitoring
NCT03905759Preoperative Colchicine, Dronedarone Or Amiodarone for Prophylaxis Against Postoperative Atrial Fibrillation in Patients Undergoing On-pump CABG; A Comparative StudyUNKNOWNINTERVENTIONALDronedarone, Amiodarone, Colchicine
NCT03856632Novel Medical Adjunctive Therapy to Catheter Ablation For Atrial Fibrillation (AF)ACTIVE NOT RECRUITINGINTERVENTIONALLiraglutide, RFM, Anti Arrhythmics
NCT03720639Confirm Rx™ Versus Reveal LINQ™ -Which is More Reliable in Data Transmission? A Randomized Clinical StudyCOMPLETEDINTERVENTIONALAbbott, Inc Confirm Rx™ versus Medtronic, Inc Reveal LINQTM
NCT03777631STroke Secondary Prevention With Catheter ABLation and EDoxaban for Patients With Non-valvular Atrial Fibrillation: STABLED StudyUNKNOWNINTERVENTIONALCatheter ablation
NCT03310125Colchicine For The Prevention Of Perioperative Atrial Fibrillation In Patients Undergoing Thoracic Surgery (COP-AF)COMPLETEDINTERVENTIONALColchicine, Placebo
NCT03259893Boston Medical Center Secondary Prevention of Atrial Fibrillation Randomized Pilot StudyTERMINATEDINTERVENTIONALAliveCor mobile ECG cardiac monitor, AF Program, Standard of care
NCT02582190Colchicine for the Prevention of Atrial Fibrillation Recurrence After Electrical Cardioversion of Persistent Atrial Fibrillation.WITHDRAWNINTERVENTIONALColchicine group
NCT03345615Standard Versus Intensive Monitoring After Myocardial Infarction Looking for Atrial FibrillationUNKNOWNINTERVENTIONAL30-day ambulatory cardiac event monitor
NCT02830152Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage: A Multicenter Randomized Clinical TrialACTIVE NOT RECRUITINGINTERVENTIONALLAAO, Medical Therapy
NCT03377465Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and PrognosisCOMPLETEDINTERVENTIONALADMA (asymmetric dimethylarginine) , NTproBNP (N-terminal pro b-type natriuretic peptide), IL-6 (Interleukin 6), Adiponectina, Leptine, Syndecan, Resistin
NCT02710669Comparison of (R) and (S) Propafenone for Prevention of Atrial Fibrillation InductionTERMINATEDINTERVENTIONAL(R)-propafenone, (S)-Propafenone, Placebo
NCT03857711Multicenter Randomized Clinical Trial PULVAB (Prophylactic Pulmonary Veins Ablation)UNKNOWNINTERVENTIONALConventional CABG, CABG+ PVI, CABG+ PVI+amiodarone
NCT02905032Shared Decision Making for Stroke Prevention in Atrial Fibrillation (SDM4Afib): A Randomized TrialCOMPLETEDINTERVENTIONALDecision Aid
NCT02507986Mobile Phones in Cryptogenic Stroke Patients Bringing Single Lead ECGs to Detect Atrial FibrillationTERMINATEDINTERVENTIONALSingle lead ECG device, 7-Day Holter monitor.
NCT02646267The Efficacy and Safety of Dabigatran Etexilate and Different Intensity Warfarin for the Prevention of Stroke and Systemic Embolism in Patients With Non-valvular Atrial FibrillationUNKNOWNINTERVENTIONALstandard intensity warfarin, low intensity warfarin, dabigatran etexilate
NCT02168829The Optimal Anticoagulation for Enhanced Risk Patients Post-Catheter Ablation for Atrial Fibrillation TrialCOMPLETEDINTERVENTIONALRivaroxaban, Acetylsalicylic acid
NCT02702752Dynamic Changes in Stromal Cell-derived Factor-1α Levels in Acute and Stabilized Heart Disease - ACUTE MYOCARDIAL INFARCTION, ATRIAL FIBRILLATION, AND HEART FAILURE (THE DYNASDY STUDY)UNKNOWNINTERVENTIONALDYNASDY
NCT02428140Post-Embolic Rhythm Detection With Implantable Versus External Monitoring: Pilot and Feasibility StudyCOMPLETEDINTERVENTIONALMedtronic Reveal LINQ, Sorin Spiderflash-t
NCT02358655Canadian Community Utilization of Stroke Prevention Study - Emergency DepartmentCOMPLETEDINTERVENTIONALRetrospective review of OAC prescription, Prescription of OAC in ED, Community AF clinic
NCT02467166A Prospective, Non-Randomized Study to Evaluate the CIRCA Esophageal Temperature Monitoring System in Prevention of Esophageal Lesions Following Atrial Fibrillation Radiofrequency Catheter AblationCOMPLETEDINTERVENTIONALCirca™ Probe

Genetic associations (0)

None linked.