C
Betaine
Novel & Emerging BiomarkersLab test / biomarkerunclearpartially modifiable
10
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 7genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. — Nature 2011 · PMID 21475195
Clinical trials (4)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT06758856 | ABC (Additional Betaine and Choline) Study: Effect of Betaine and Choline Intake on Biomarkers of Metabolic Health in Humans | COMPLETED | INTERVENTIONAL | Trimethylglycine, Eggs, Cellulose |
| NCT01371357 | The Effects of 8-week Choline, Betaine, and Folic Acid Supplementation on Plasma Homocysteine Concentration During Guanidinoacetic Acid Loading in Young Healthy Volunteers | COMPLETED | INTERVENTIONAL | TEST 1, TEST 2, TEST 3 |
| NCT00102843 | Effect of Lowering of Fasting Plasma Homocysteine Concentrations Through Supplementation With Betaine or Folic Acid on Vascular Function in Healthy Volunteers | COMPLETED | INTERVENTIONAL | supplementation with folic acid and betaine |
| NCT00126347 | Effect of Lowering of Plasma Homocysteine Concentrations After an Oral Methionine Load on Vascular Function in Healthy Volunteers | COMPLETED | INTERVENTIONAL | supplementation with betaine, serine, and folic acid |
Genetic associations (0)
None linked.