C
C-reactive protein (hs-CRP)
Inflammatory & ImmuneLab test / biomarkerriskpartially modifiable
11
evidence score
Also known as: elevated high-sensitivity C-reactive protein, elevated hsCRP
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 8.4genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection. — Circulation research 2016 · PMID 26837745
Clinical trials (6)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT07693868 | An NNC6022-0004 Single and Multiple Ascending Dose Study Investigating Safety, Tolerability, Pharmacokinetics, Food Effect and Target Engagement in Healthy Adults Including a Single Cohort in Adults Living With Obesity | NOT YET RECRUITING | INTERVENTIONAL | NNC6022-0004, Placebo |
| NCT07566325 | Effects of Avocado Consumption on Inflammation and Insulin Sensitivity in Adults With Elevated High Sensitivity-C-reactive Protein (Hs-CRP): A Randomized, Controlled Crossover Trial | NOT YET RECRUITING | INTERVENTIONAL | Avocado, Control |
| NCT07477301 | Supportive Psychotherapy As An Adjunct To Risperidone Improves Cognitive Function And Reduces High-Sensitivity C-Reactive Protein (Hs-CRP) In Schizophrenia: A Randomized Controlled Trial | COMPLETED | INTERVENTIONAL | Structured Supportive Psychotherapy, Risperidone 2 mg |
| NCT06362759 | A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Quarterly and Monthly TOUR006 in Participants With Chronic Kidney Disease and Elevated High-Sensitivity C-Reactive Protein | COMPLETED | INTERVENTIONAL | TOUR006 - 50 MG, TOUR006 - 25 MG, TOUR006 - 15 MG |
| NCT04126330 | Effect of Omega-3 and Probiotic Dietary Supplements on Elevated High Sensitivity C-reactive Protein (Hs-CRP) as a Marker of Low-grade Inflammation: Targeting Inflammation and Intestinal Barrier Function in the Elderly and Obese | COMPLETED | INTERVENTIONAL | Probiotic, Omega-3, Vitamin D supplement, Placebo |
| NCT07513922 | Correlation Between hs CRP TG Triglycerides Glucose Index in NAFLD and Liver Fibrosis | NOT YET RECRUITING | OBSERVATIONAL | • Fasting triglycerides (TG) • Fasting plasma glucose • High-sensitivity C-reactive protein (hs-CRP) • Liver enzymes (ALT, AST, GGT) • Platelet count • HbA1c • Lipid profile (total cholesterol, HDL-C, |
Genetic associations (0)
None linked.