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C-reactive protein

Inflammatory & ImmuneLab test / biomarkerriskmodifiable
34
evidence score

Also known as: C reactive protein, C-reactive protein (CRP), C-reactive protein (CRP) concentration, C-reactive protein > or =3 mg/L, CRP

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 12.6meta-analyses: 6trials: 14.9genetic: 0MR bonus:

References (17)

1 meta-analyses / systematic reviews

Clinical trials (30)

NCTTitleStatusTypeInterventions
NCT06561971Evaluating the Effect of Smoking Amount on Determining Salivary High Sensitive C-Reactive Protein(Hs-CRP) Values by Centrifuging the Saliva of the Same Individuals at Different Rpm and Time.RECRUITINGINTERVENTIONALsaliva obtaining
NCT07693868An NNC6022-0004 Single and Multiple Ascending Dose Study Investigating Safety, Tolerability, Pharmacokinetics, Food Effect and Target Engagement in Healthy Adults Including a Single Cohort in Adults Living With ObesityNOT YET RECRUITINGINTERVENTIONALNNC6022-0004, Placebo
NCT07566325Effects of Avocado Consumption on Inflammation and Insulin Sensitivity in Adults With Elevated High Sensitivity-C-reactive Protein (Hs-CRP): A Randomized, Controlled Crossover TrialNOT YET RECRUITINGINTERVENTIONALAvocado, Control
NCT07477301Supportive Psychotherapy As An Adjunct To Risperidone Improves Cognitive Function And Reduces High-Sensitivity C-Reactive Protein (Hs-CRP) In Schizophrenia: A Randomized Controlled TrialCOMPLETEDINTERVENTIONALStructured Supportive Psychotherapy, Risperidone 2 mg
NCT06952231Comparison of Effect of Sitagliptin and Empagliflozin in Combination With Metformin on High-Sensitivity C-Reactive Protein Levels in Patients With Type 2 Diabetes MellitusCOMPLETEDINTERVENTIONALSitagliptin + Metformin, Empagliflozin + Metformin
NCT06362759A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Quarterly and Monthly TOUR006 in Participants With Chronic Kidney Disease and Elevated High-Sensitivity C-Reactive ProteinCOMPLETEDINTERVENTIONALTOUR006 - 50 MG, TOUR006 - 25 MG, TOUR006 - 15 MG
NCT07230873The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive Protein Levels in Overweight WomenCOMPLETEDINTERVENTIONALCombined Exercise Group, No Structured Exercise
NCT06078904The Effects of Different Doses of Colchicine on High-sensitivity C-reactive Protein in Patients After Percutaneous Coronary InterventionCOMPLETEDINTERVENTIONALColchicine 0.5 MG, Colchicine 0.375 MG, Colchicine 0.25 MG
NCT06025071Efficacy and Safety of Residual Inflammatory Risk-Guided Low-dose Colchicine Therapy in Elderly Patients With Multivessel Coronary Artery Disease: A Multicenter Randomized Controlled TrialUNKNOWNINTERVENTIONALcolchicine
NCT05130892Effect of Inflammasome Inhibitor on High-sensitivity C-reactive Protein in Patients After Percutaneous Coronary InterventionCOMPLETEDINTERVENTIONALColchicine, Tranilast, Oridonin
NCT05614362The Effect of Channa Striatus Extract on Serum Albumin and High Sensitive C-Reactive Protein in End-Stage Renal Disease PatientsCOMPLETEDINTERVENTIONALChanna Striatus extract, Maltodextrin
NCT04126330Effect of Omega-3 and Probiotic Dietary Supplements on Elevated High Sensitivity C-reactive Protein (Hs-CRP) as a Marker of Low-grade Inflammation: Targeting Inflammation and Intestinal Barrier Function in the Elderly and ObeseCOMPLETEDINTERVENTIONALProbiotic, Omega-3, Vitamin D supplement, Placebo
NCT03704766Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic ArthritisUNKNOWNINTERVENTIONALSynovial Alpha-defensin assay, Synovial Neutrophil elastase assay, Synovial lactate assay
NCT01900600Substudy of the the CANTOS Trial (Interleukin-1 Blockade With Canakinumab to Improve Exercise Capacity in Patients With Chronic Systolic Heart Failure and Elevated Hs-CRP; CACZ885M2301)COMPLETEDINTERVENTIONALCardiopulmonary exercise test, Echocardiogram
NCT01755949Impact and Time Course of Colchicine Therapy on C-reactive Protein Elevation in Chronic Atrial Fibrillation (AF) and Post AF AblationCOMPLETEDINTERVENTIONALColchicine, 0.6 mg PO BID, Matching placebo
NCT02127177Long-term Effects of Continuous Positive Airway Pressure on Lipidemia and High-sensitivity C-reactive Protein Levels in Nonobese Patients With Coronary Heart Disease and Obstructive Sleep ApneaCOMPLETEDINTERVENTIONALContinuous Positive Airway Pressure Ventilator
NCT02165228A Stress Reduction Strategy for Decreasing CVD Risk Through C-reactive Protein ReductionCOMPLETEDINTERVENTIONALMindfulness-based stress reduction, Nutrition Enhancement
NCT00655993Effect of Statin Therapy on C-reactive Protein Levels in Patients With COPDCOMPLETEDINTERVENTIONALsimvastatin
NCT00715169Phase 2 A, Double-Blind, Randomized, Placebo-Controlled Trial Measuring the Effects of MLN1202 on C-Reactive Protein Levels in Patients With Risk Factors for Cardiovascular DiseaseCOMPLETEDINTERVENTIONALMLN1202, Placebo
NCT00343876A Single Center, Double-Blind, Randomized Trial to Evaluate the Effects of Aspirin 325 mg + Clopidogrel 75 mg v. Aspirin 325 mg + Placebo on Plasma Concentration of C-Reactive Protein: The CATER Trial ProtocolCOMPLETEDINTERVENTIONALaspirin, clopidogrel
NCT07513922Correlation Between hs CRP TG Triglycerides Glucose Index in NAFLD and Liver FibrosisNOT YET RECRUITINGOBSERVATIONAL• Fasting triglycerides (TG) • Fasting plasma glucose • High-sensitivity C-reactive protein (hs-CRP) • Liver enzymes (ALT, AST, GGT) • Platelet count • HbA1c • Lipid profile (total cholesterol, HDL-C,
NCT07130721Assessment of Blood Biomarkers (D-dimer and C-Reactive Protein) in Predicting Cardiovascular Complications Among Hemodialysis Patients: A Cross-Sectional StudyNOT YET RECRUITINGOBSERVATIONALC-Reactive Protein (CRP) Test, D-dimer Test, Electrocardiogram (ECG)
NCT05845112Start Taking Action For TB Diagnosis (START4ALL)COMPLETEDOBSERVATIONALClass 1, Point of Care (POC) Quantitative C-Reactive Protein (CRP)., Class 2, POC Qualitative/Semiquantitative CRP, Class 3, Urine Lateral Flow Tests
NCT05164965C-reactive Protein and Homocysteine and Their Interaction Contribute to Postoperative DeliriumUNKNOWNOBSERVATIONAL
NCT05479565The Association of Reduced Arterial Stiffness and Highly Sensitive C-reactive Protein With Gestational Diabetes Mellitus.COMPLETEDOBSERVATIONALvenous blood sample for determining the value of highly sensitive C-reactive C protein from serum
NCT03830060Clinical Usefulness of Cortisol, Antinuclear Antibodies and High-sensitivity C-reactive Protein in Diagnostic and Prognostic Evaluation of Acute PancreatitisUNKNOWNOBSERVATIONALMeasurement of cortisol
NCT04305171Effect of Non-surgical Periodontal Treatment on Plasma Fibrinogen, Plasminogen Activator Inhibitor 1 and C-reactive Protein Levels in Cardiovascular Disease Patients With PeriodontitisCOMPLETEDOBSERVATIONALnon-surgical periodontal treatment
NCT03345745The Short-Term Effects of Non-Surgical Periodontal Therapy on The Saliva Levels of S100A12, High-Sensitivity C-Reactive Protein and Fetuin-A in Patients With Gingivitis and Chronic PeriodontitisCOMPLETEDOBSERVATIONALsalivary samples
NCT01645228Could Non-invasive Biochemical, Image or Physiological Index Predict Significant Coronary Arterial Stenosis in Symptomatic Adults?UNKNOWNOBSERVATIONALcoronary calcium score measurement, high sensitivity C reactive protein measurement, ankle brachial index measurement
NCT00021918Serum Total Homocysteine and C-Reactive Protein - Ancillary to IDNTCOMPLETEDOBSERVATIONAL

Genetic associations (0)

None linked.