A
Cadmium exposure
Environmental & OccupationalBehavior / exposureriskmodifiable
35
evidence score
Also known as: Cadmium, Cadmium (Cd) exposure, cadmium, cadmium exposure (urinary), urinary cadmium concentration
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 17.6meta-analyses: 17.6trials: 0genetic: 0MR bonus:
References (57)
6 meta-analyses / systematic reviews- METACadmium exposure and cardiovascular disease risk: A systematic review and dose-response meta-analysis. — Environmental pollution (Barking, Essex : 1987) 2024 · PMID 38295933
- METACadmium and atherosclerosis: A review of toxicological mechanisms and a meta-analysis of epidemiologic studies. — Environmental research 2018 · PMID 29358116
- METAEnvironmental toxic metal contaminants and risk of cardiovascular disease: systematic review and meta-analysis — BMJ 2018 · PMID 30158148
- METAEnvironmental Metals and Cardiovascular Disease in Adults: A Systematic Review Beyond Lead and Cadmium. — Current environmental health reports 2016 · PMID 27783356
- METAUrinary cadmium and mortality from all causes, cancer and cardiovascular disease in the general population: systematic review and meta-analysis of cohort studies. — International journal of epidemiology 2015 · PMID 25997435
- METACadmium exposure and clinical cardiovascular disease: a systematic review. — Current atherosclerosis reports 2013 · PMID 23955722
- Associations between heavy metal exposure and vascular age: a large cross-sectional study. — Journal of translational medicine 2025 · PMID 39754096
- Associations Between Lead and Cadmium Exposure and Subclinical Cardiovascular Disease in U.S. Adults. — Cardiovascular toxicology 2025 · PMID 39873882
- Association between heavy metals and risk of cardiovascular diseases in US adults with prediabetes from NHANES 2011-2018. — BMC public health 2025 · PMID 39885432
- Combined Effects of Arsenic, Cadmium, and Mercury with Cardiovascular Disease Risk: Insights from the All of Us Research Program. — International journal of environmental research and public health 2025 · PMID 40003465
- Exposure to Lead and Coronary Artery Atherosclerosis: A Swedish Cross-Sectional Population-Based Study. — Journal of the American Heart Association 2025 · PMID 40035389
- Oxidative stress and inflammation mediate the adverse effects of cadmium exposure on all-cause and cause-specific mortality in patients with diabetes and prediabetes. — Cardiovascular diabetology 2025 · PMID 40158078
- Association of blood cadmium levels with all-cause and cause-specific mortality among adults with non-alcoholic fatty liver disease: a prospective cohort study. — Frontiers in public health 2025 · PMID 40255375
- Caffeine Intake Attenuates the Association of Cadmium Exposure with Cardiovascular Disease: National Health and Nutrition Examination Survey (NHANES) 2003-2016. — Cardiovascular toxicology 2025 · PMID 40650791
- Cadmium exposure and advanced cardiovascular-kidney-metabolic syndrome: An integrated multi-organ perspective based on epidemiology and adverse outcome pathways. — Ecotoxicology and environmental safety 2025 · PMID 40819402
- Heavy metal pollution and ischemic stroke: multimechanistic pathogenesis and countermeasures. — Frontiers in public health 2025 · PMID 40951398
- Synergistic effects of cadmium exposure and hypertension on all-cause and cardiovascular mortality in individuals with prediabetes. — Ecotoxicology and environmental safety 2025 · PMID 41066817
- Heavy metals and mortality in cardiovascular-kidney-metabolic syndrome: Insights from the NHANES cohort. — Medicine 2025 · PMID 41367030
- Environmental exposure to lead and cadmium are associated with triglyceride glucose index. — Scientific reports 2024 · PMID 38291186
- Heavy Metal Exposure and Cardiovascular Disease — Circulation Research 2024 · PMID 38662861
- Associations of serum lead, cadmium, and mercury concentrations with all-cause and cause-specific mortality among individuals with cardiometabolic multimorbidity. — Ecotoxicology and environmental safety 2024 · PMID 38852466
- Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA). — Circulation 2024 · PMID 39087344
- Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis. — Journal of the American College of Cardiology 2024 · PMID 39297845
- Potential pathogenic roles of ferroptosis and cuproptosis in cadmium-induced or exacerbated cardiovascular complications in individuals with diabetes. — Frontiers in endocrinology 2024 · PMID 39415790
- Association between exposure to urinary metal and all-cause and cardiovascular mortality in US adults. — PloS one 2024 · PMID 39729492
- Cadmium contributes to atherosclerosis by affecting macrophage polarization. — Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 · PMID 36639048
- Association of Endocrine-Disrupting Chemicals with All-Cause and Cause-Specific Mortality in the U.S.: A Prospective Cohort Study. — Environmental science & technology 2023 · PMID 36728834
- Chronic Kidney Disease Induced by Cadmium and Diabetes: A Quantitative Case-Control Study. — International journal of molecular sciences 2023 · PMID 37240395
- Contaminant Metals as Cardiovascular Risk Factors: A Scientific Statement From the American Heart Association. — Journal of the American Heart Association 2023 · PMID 37306302
- Cadmium Exposure and Cardiovascular Diseases. — Chemical research in toxicology 2023 · PMID 37580125
- Urinary cadmium was linearly and positively associated with cardiac infarction/injury score and subclinical myocardial injury in the general population without cardiovascular diseases and chronic kidney disease. — International urology and nephrology 2023 · PMID 37898564
- Long-term cadmium exposure and fractures, cardiovascular disease, and mortality in a prospective cohort of women. — Environment international 2022 · PMID 35114608
- Associations of exposure to lead and cadmium with risk of all-cause and cardiovascular disease mortality among patients with type 2 diabetes. — Environmental science and pollution research international 2022 · PMID 35670945
- Occupational risk factors for hypertension. — Journal of hypertension 2022 · PMID 35950984
- Endothelial Dysfunction Induced by Cadmium and Mercury and its Relationship to Hypertension. — Current hypertension reviews 2021 · PMID 33475076
- Low-Level Cadmium Exposure and Atherosclerosis. — Current environmental health reports 2021 · PMID 33754286
- Review of cadmium exposure and smoking-independent effects on atherosclerotic cardiovascular disease in the general population. — Journal of internal medicine 2021 · PMID 34157165
- Cadmium and cardiovascular disease: An overview of pathophysiology, epidemiology, therapy, and predictive value. — Revista portuguesa de cardiologia 2021 · PMID 34392906
- Cadmium exposure and growth differentiation factor-15 (GDF-15) levels in non-smoking older adults. — Environmental research 2021 · PMID 34695433
- Chronic cadmium exposure and cardiovascular disease in adults. — Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 2020 · PMID 32149559
- Association of Blood Cadmium with Cardiovascular Disease in Korea: From the Korea National Health and Nutrition Examination Survey 2008-2013 and 2016. — International journal of environmental research and public health 2020 · PMID 32872339
- Arsenic, cadmium, and mercury-induced hypertension: mechanisms and epidemiological findings. — Journal of toxicology and environmental health. Part B, Critical reviews 2018 · PMID 29446707
- Low-level lead exposure and mortality in US adults: a population-based cohort study — The Lancet Public Health 2018 · PMID 29544878
- Prevalence of exposure of heavy metals and their impact on health consequences. — Journal of cellular biochemistry 2017 · PMID 28643849
- Cadmium and Cadmium/Zinc Ratios and Tobacco-Related Morbidities. — International journal of environmental research and public health 2017 · PMID 28961214
- Oxidative Stress and Cardiovascular Dysfunction Associated with Cadmium Exposure: Beneficial Effects of Curcumin and Tetrahydrocurcumin. — The Tohoku journal of experimental medicine 2016 · PMID 27151191
- Interrelation of Cadmium, Smoking, and Cardiovascular Disease (from the National Health and Nutrition Examination Survey). — The American journal of cardiology 2016 · PMID 27316775
- Metal pollutants and cardiovascular disease: mechanisms and consequences of exposure. — American heart journal 2014 · PMID 25458643
- Cadmium exposure and incident cardiovascular disease. — Epidemiology (Cambridge, Mass.) 2013 · PMID 23514838
- Cadmium in diet and risk of cardiovascular disease in women. — Epidemiology (Cambridge, Mass.) 2013 · PMID 24030503
- Heavy Metal Poisoning and Cardiovascular Disease — Journal of Toxicology 2011 · PMID 21912545
- Cadmium and cardiovascular diseases: cell biology, pathophysiology, and epidemiological relevance. — Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2010 · PMID 20213268
- Cadmium and peripheral arterial disease: gender differences in the 1999-2004 US National Health and Nutrition Examination Survey. — American journal of epidemiology 2010 · PMID 20693268
- Cadmium exposure and cardiovascular disease in the 2005 Korea National Health and Nutrition Examination Survey. — Environmental research 2010 · PMID 21055738
- Cadmium Is a Novel and Independent Risk Factor for Early Atherosclerosis Mechanisms and In Vivo Relevance — Arteriosclerosis Thrombosis and Vascular Biology 2009 · PMID 19556524
- Cadmium exposure and hypertension in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). — Environmental health perspectives 2008 · PMID 18197299
- Environmental Cardiology — Circulation Research 2006 · PMID 17008598
Clinical trials (0)
None linked.
Genetic associations (0)
None linked.