C
Carotid artery disease
Comorbid ConditionsDisease / conditionriskpartially modifiable
20
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 4.8meta-analyses: 0trials: 15genetic: 0MR bonus:
References (2)
0 meta-analyses / systematic reviews- Coronary artery bypass grafting for left main disease and the risk of stroke: Incidence, aetiology and prevention. — The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 2016 · PMID 27720167
- Genome-wide association studies of late-onset cardiovascular disease. — Journal of molecular and cellular cardiology 2015 · PMID 25870159
Clinical trials (55)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT07200180 | Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery (PAIRS Trial) | RECRUITING | INTERVENTIONAL | Аrgon-oxygen breathing mixture, Nitrogen-oxygen breathing mixture |
| NCT06924593 | Study on the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System for Carotid Artery Revascularization During Endovascular Treatment | RECRUITING | INTERVENTIONAL | Trans-Carotid Artery Occlusion Shunt System |
| NCT07104487 | An Exploratory Study of [18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease | RECRUITING | INTERVENTIONAL | [18F]AlF-OC |
| NCT06959628 | Study on the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets for Cerebral Protection During Carotid Angioplasty | RECRUITING | INTERVENTIONAL | Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets |
| NCT04261478 | A Multi-centre, Prospective, Randomized, Open-label, Blinded Endpoint (PROBE) Controlled Trial Comparing Cervical Internal Carotid Artery Stenting to no Stenting During Thrombectomy for Tandem Occlusion Stroke | RECRUITING | INTERVENTIONAL | Carotid artery stenting, Antiplatelet Agents |
| NCT06864299 | Study on the Safety and Efficacy of the Trans-Carotid Artery Occlusion Shunt System Combined With Introducer Sets for Cerebral Protection During Carotid Angioplasty | COMPLETED | INTERVENTIONAL | Trans-Carotid Artery Occlusion Shunt System Combined with Introducer Sets |
| NCT05845710 | Protection Against Emboli During caRotid Artery Stenting Using a Neuroguard IEP® Direct 3-in-1 Delivery System Comprised oF a pOst-dilation Balloon, integRated eMbolic Filter, and A Novel Carotid stEnt - the PERFORMANCE III Study | COMPLETED | INTERVENTIONAL | Neuroguard IEP Direct System |
| NCT05574972 | A Prospective, Multi-center and Randomized Controlled Clinical Trial to Evaluate the Efficacy and Safety of Timing Carotid Stent for Carotid Artery Stenosis（Timing Trial） | UNKNOWN | INTERVENTIONAL | Timing Carotid Stent, Carotid Wallstent |
| NCT05416853 | Radial Versus Femoral Access For Carotid Artery Stenting In Patients With Carotid-Artery Stenosis ：a Prospective, Randomized, Multicenter, Noninferiority Trial | ACTIVE NOT RECRUITING | INTERVENTIONAL | Carotid Artery Stenting (CAS) |
| NCT05126238 | A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction: A Double-Blind, Placebo Control Randomized Trial (BINOS) | TERMINATED | INTERVENTIONAL | Lithium Carbonate, Placebo |
| NCT04470687 | Innovative Applications of Ultrafast Ultrasound Imaging in Peripheral Vascular Pathology: Evaluation of Carotid Plaque Vulnerability by Quantification of Neovascularization | COMPLETED | INTERVENTIONAL | contrast enhanced ultrafast ultrasound imaging |
| NCT04730973 | CARotid plaqUe StabilizatiOn and Regression With Evolocumab: the CARUSO Study | UNKNOWN | INTERVENTIONAL | Evolocumab, lipid-lowering therapy (LLT) |
| NCT04201132 | Protection Against Emboli During Carotid Artery Stenting Using a 3-in-1 Delivery System Comprised of a Post-dilation Balloon, Integrated Embolic Filter and a Novel Carotid Stent - the PERFORMANCE II Study | ACTIVE NOT RECRUITING | INTERVENTIONAL | Carotid artery stenting with Neuroguard IEP System |
| NCT04255316 | Modified Method of Eversion Carotid Endarterectomy in Patients With Extensive Atherosclerotic Disease of Carotid Bifurcation | COMPLETED | INTERVENTIONAL | Modified method of eversion carotid endarterectomy, Standard method of eversion carotid endarterectomy |
| NCT04271033 | Long-term Outcomes of MicroNet-covered Stent Routine Use for Stroke Prevention in Symptomatic and Increased-risk Asymptomatic Carotid Stenosis Patients Requiring Revascularization by Neurovascular Team Decision: PARADIGM-EXTEND | UNKNOWN | INTERVENTIONAL | Carotid Artery Stenting |
| NCT02629653 | Body Cooling During Carotid Endarterectomy: No-profit, Open, Mono-centric, Feasibility Study | COMPLETED | INTERVENTIONAL | endovascular cooling (Zoll system) |
| NCT01968226 | An Exploratory, Phase II, Open Label, Single-Center, Non-Randomized Study Of [F-18] RGD-K5 Positron Emission Tomography (PET) In Participants With Carotid Artery Stenosis | TERMINATED | INTERVENTIONAL | [F-18] RDG-K5 |
| NCT01445613 | CANOPY: Carotid Artery Stenting Outcomes in the Standard Risk Population for Carotid Endarterectomy | COMPLETED | INTERVENTIONAL | RX Acculink Carotid Stent System (RX Acculink) |
| NCT01414387 | Effects of Cerebral Protection With Filters vs. Flow Reversal on Cerebral Embolization After Carotid Artery Stenting | TERMINATED | INTERVENTIONAL | Carotid filter, Carotid reversal of flow |
| NCT01133327 | Adapt™ Monorail™ Carotid Stent System: A Postmarket Clinical Follow-up Study | COMPLETED | INTERVENTIONAL | Carotid Artery Stenting |
| NCT01210937 | Early Warning and Optimization Strategy in Carotid Endarterectomy | UNKNOWN | INTERVENTIONAL | CEA and TCD monitoring |
| NCT02133807 | A 72-week, Prospective, Parallel-group, Partially Blinded, Controlled Phase IIIb Study Evaluating the Impact of Specific Lp(a) Apheresis on Atherosclerotic Disease Burden in Coronary Heart Disease Patients With High Lipoprotein(a) Level. | COMPLETED | INTERVENTIONAL | Specific Lp(a) apheresis |
| NCT00711919 | Pitavastatin Evaluation of Atherosclerosis Regression by Intensive Cholesterol-Lowering Therapy | UNKNOWN | INTERVENTIONAL | Pitavastatin, Pitavastatin |
| NCT00287508 | Emboshield and Xact Post Approval Carotid Stent Trial Using the Emboshield® BareWire™ Rapid Exchange Embolic Protection System and Xact® Rapid Exchange Carotid Stent System | COMPLETED | INTERVENTIONAL | Carotid artery stenting with filter (interventional) |
| NCT00178672 | A Single Center IDE Study on Carotid Stenting With Distal Protection for the Treatment of Obstructive Carotid Artery Disease | COMPLETED | INTERVENTIONAL | Angioguard XP distal protection device, Heart Catheterization -Angioplasty, stenting |
| NCT00316108 | Boston Scientific EPI: A Carotid Stenting Trial for High-Risk Surgical Patients | COMPLETED | INTERVENTIONAL | WALLSTENT® Endoprosthesis™ |
| NCT07166731 | High Coverage CARotid Stenting vs. Medical Management Alone to Prevent EmboliSm From symptomaTic Non-stenotic cARotid Disease (SyNC) - CARESTAR | RECRUITING | OBSERVATIONAL | |
| NCT07296965 | The Role of the Oral Microbiome in Carotid Atherosclerosis: Investigating in a Cross-sectional Study the Microbial Influence on Plaque Development and Vulnerability Based on Biobank Data | RECRUITING | OBSERVATIONAL | Sample Collection |
| NCT06546761 | Selective Coronary Revascularization in Carotid Artery Disease Patients After Carotid Revascularization (SCORECAD Trial) | RECRUITING | OBSERVATIONAL | Coronary CT angiography and FFRct analysis |
| NCT05800821 | Prediction of Cerebral Hyperperfusion Syndrome After Carotid Revascularization Using Deep Learning | RECRUITING | OBSERVATIONAL | Carotid revascularization |
| NCT05539781 | Change of Hemodynamics and Cerebral Functions After Carotid Artery Revascularization | RECRUITING | OBSERVATIONAL | |
| NCT06882954 | The Management of Asymptomatic Carotid Stenosis: Monocentric Experience | RECRUITING | OBSERVATIONAL | |
| NCT06211725 | The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Patients With Asymptomatic Carotid Artery Stenosis | UNKNOWN | OBSERVATIONAL | |
| NCT06058507 | "The Incidence of Carotid Web and Its Radiological Classification, Determination of Its Relationship With Ischemic Stroke by Evaluating the Clinical Data and Vascular Risk Factors of Carotid Web Cases" | COMPLETED | OBSERVATIONAL | CT angiography |
| NCT05296876 | Multi-dimensional Evaluation of Carotid Artery Stenosis and Prediction of Brain Function After Endarterectomy by SSPC System | UNKNOWN | OBSERVATIONAL | Carotid endarterectomy (CEA) |
| NCT03668821 | Vascular Frailty - An Observational Cohort Study | UNKNOWN | OBSERVATIONAL | Questionnaire |
| NCT04679727 | Detecting the Vulnerable Carotid Plaque: "The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study" - Implications for Stroke and Cognitive Decline Prediction in Asymptomatic Carotid Artery Disease | UNKNOWN | OBSERVATIONAL | |
| NCT04947046 | Carotid Stenosis Management During COVID-19 Era - Best Medical Intervention Alone (CASCOM Pilot Study): A Prospective Observational Study | UNKNOWN | OBSERVATIONAL | |
| NCT04234854 | OPTIMAl Endovascular Exclusion of High-risk Carotid Plaque Using the CGuard™ Stent in Patients With Symptoms or Signs of Carotid Stenosis-related Brain Injury: IVUS Controlled Investigator Initiated Multcentric Multi-specialty Study | UNKNOWN | OBSERVATIONAL | Intravascular Utrasound (IVUS) of Carotid Artery after implantation of CGuard stent |
| NCT03982420 | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Evaluation | COMPLETED | OBSERVATIONAL | Transcarotid Revascularization (TCAR) |
| NCT03721523 | Observational Cohort Study of Changes in Carotid Plaque Volume After Stroke. | WITHDRAWN | OBSERVATIONAL | 3 Dimensional tomographic Ultrasound, Platelet Aggregometry |
| NCT05134493 | Embolic Signals Detection Study (Esds) in Candidates for Surgical Carotid Revascularisation: a Comparison With Plaque Histological Findings | COMPLETED | OBSERVATIONAL | |
| NCT03217214 | Investigation of a Non-invasive/ Minimally Contact Based Method for Diagnosis of Cardiovascular Disease: Blockage(Stenosis) and Blood Flow | COMPLETED | OBSERVATIONAL | Thermography |
| NCT03985774 | The ENROUTE Transcarotid Neuroprotection System (ENROUTE Transcarotid NPS) DW-MRI Study | COMPLETED | OBSERVATIONAL | Transcarotid revascularization |
| NCT02124928 | Morphological and Serological Criteria of Plaque Vulnerability: Risk Assessment for Symptomatic and Asymptomatic Carotid Artery Stenosis | UNKNOWN | OBSERVATIONAL | Carotid endarterectomy |
| NCT02450721 | Clinical and Laboratory Biomarkers in Patients With Atherothrombotic Stroke | UNKNOWN | OBSERVATIONAL | Biomarkers serum level measurement |
| NCT01449617 | Observational Study on Predictive Value for Vascular Events of Residual Platelet Aggregation in Patients on Antiplatelet Therapy After Carotid Angioplasty With Stenting | UNKNOWN | OBSERVATIONAL | Aspirin plus clopidogrel |
| NCT01042912 | A Single-centered Investigation Into the Frequency Domain Patterns in the Carotid Vessel in Patients With Suspected Stenosis | WITHDRAWN | OBSERVATIONAL | |
| NCT00597974 | Evaluation of Neurological Outcome in Patients Undergoing Cerebral Angiography and Revascularization Using Angioplasty and Stent-Supported Angioplasty | COMPLETED | OBSERVATIONAL | Angioplasty, Stent, Neurological and neuropsychological evaluations |
| NCT00070668 | Inflammatory Genomics in Human Carotid Artery Disease | COMPLETED | OBSERVATIONAL | |
| NCT00597883 | Neurologic and Neuropsychometric Outcome in Patients Undergoing Carotid Endarterectomy | COMPLETED | OBSERVATIONAL | Carotid endarterectomy, Neurological and neuropsychological evaluations |
| NCT00005459 | Risk of Coronary Heart Disease in Women With Polycystic Ovary Syndrome | COMPLETED | OBSERVATIONAL | |
| NCT00011258 | Paraoxonase and LDL Oxidation in Carotid Artery Disease | COMPLETED | OBSERVATIONAL | Paraoxonase |
| NCT00005696 | Early Atherosclerosis Change in Two Clinical Trials | COMPLETED | OBSERVATIONAL | |
| NCT00005134 | Strong Heart Study | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.