C
Cerebral small vessel disease
Comorbid ConditionsDisease / conditionriskpartially modifiable
17
evidence score
Also known as: Small vessel disease, small vessel disease
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 6meta-analyses: 0trials: 10.8genetic: 0MR bonus:
References (3)
0 meta-analyses / systematic reviews- The Cerebrovascular-Chronic Kidney Disease Connection: Perspectives and Mechanisms. — Translational stroke research 2016 · PMID 27628245
- Progress on diabetic cerebrovascular diseases. — Bosnian journal of basic medical sciences 2014 · PMID 25428668
- Cerebrovascular disease and dementia. — The British journal of radiology 2007 · PMID 18445742
Clinical trials (11)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT06525987 | Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD): a Randomized Clinical Trial | RECRUITING | INTERVENTIONAL | Physical activity |
| NCT05690997 | Effect of Intensive Blood Pressure Control on Cerebral Blood Flow and Cognition in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease | UNKNOWN | INTERVENTIONAL | Intensive treatment, Standard treatment |
| NCT05169021 | Folic Acid and Intensive Antihypertensive Therapy for Cerebrovascular and Cardiovascular Events Prevention Among Patients With Hypertension and Cerebral Small Vascular Diseases (FAITH)----A Multicenter, Randomized, Controlled, Open-label, 2x2 Factorial, Blinded End-point Trial | NOT YET RECRUITING | INTERVENTIONAL | Amlodipine folic acid 5.8mg+intensive antihypertensive therapy, Amlodipine folic acid 5.8mg+standard antihypertensive therapy, Amlodipine+intensive antihypertensive therapy |
| NCT04447599 | Study of Conjunctival and Retinal Blood Vessels for the Evaluation of the Load of Small Vessel Disease in Patients With Transient Ischemic Attacks (TIAs) and Minor Strokes | UNKNOWN | INTERVENTIONAL | photography of conjunctival vessels |
| NCT06031610 | Revascularization Effect on CSVD Burden in Carotid Artery Stenosis | RECRUITING | OBSERVATIONAL | carotid artery stenting, drug therapy |
| NCT05300997 | Translational Immunodiagnostics in Suspected Stroke (TrImS): A Two-centre, Pragmatic, Prospective, Observational Study | RECRUITING | OBSERVATIONAL | Biomarker blood draw and saliva collection |
| NCT06077305 | A Registry Study of Microcirculation Disorder After Cerebral Small Vessel Disease and Ischemic Stroke, MODEST, Research Protocol | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT04611906 | Evaluation of Small Vessel Disease by 3D-rotational Angiography | COMPLETED | OBSERVATIONAL | |
| NCT04330222 | Imaging the Arterial Pathology in Cerebral Small Vessel Disease Using 7 Tesla Magnetic Resonance Imaging | UNKNOWN | OBSERVATIONAL | 7 Tesla Magnetic Resonance Imaging, Brief Memory and Executive Test |
| NCT04108754 | Small-vessel Disease Burden and Early Risk of Stroke After Transient Ischemic Attack | COMPLETED | OBSERVATIONAL | microangiopathic burden |
| NCT02330510 | Amyloid and Glucose PET Imaging in Alzheimer and Vascular Cognitive Impairment Patients With Significant White Matter Disease | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.