C
Chronic heart failure
Comorbid ConditionsDisease / conditionriskpartially modifiable
11
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 7.8genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Periodontitis in Chronic Heart Failure. — Texas Heart Institute journal 2016 · PMID 27547136
Clinical trials (5)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT05737186 | The Efficacy and Safety of SGLT2 Inhibitors in Improving Heart Failure in Patients With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) and Severe Renal Insufficiency | TERMINATED | INTERVENTIONAL | SGLT-2 inhibitor |
| NCT04778787 | Impact of Sodium-glucose Cotransporter Type 2 Inhibitors on the Course of Cardiorenal Syndrome in Acute Decompensation of Chronic Heart Failure | COMPLETED | INTERVENTIONAL | Standard list of drugs used for acute decompensation of CHF (loop diuretics, vasodilators, digoxin, inotropic agents, vasopressors), plus dapagliflozin (Forxiga; MP-002596) |
| NCT03226457 | Renal and Cardiovascular Effect of Sodium-Glucose Co-Transporter 2 (SGLT2) Inhibition in Combination With Loop Diuretics in Diabetic Patients With Chronic Heart Failure | COMPLETED | INTERVENTIONAL | Empagliflozin 25mg, Placebo oral capsule, Frusemide |
| NCT02653482 | Dapagliflozin Effect on Symptoms and Biomarkers in Patients With Heart Failure | COMPLETED | INTERVENTIONAL | Dapagliflozin, Dapagliflozin matching placebo |
| NCT07355088 | Precision Subtyping and Prognostic Study of Heart Failure Based on Multi-Omics Integration and Clinical Indicators: A Prospective Single-Center Cohort Study | NOT YET RECRUITING | OBSERVATIONAL |
Genetic associations (0)
None linked.