A
Circulating microRNAs
Novel & Emerging BiomarkersLab test / biomarkerunclearnon modifiable
38
evidence score
Also known as: MicroRNAs, micro-rna, microrna, mirna
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 17.5meta-analyses: 11.6trials: 8.4genetic: 0MR bonus:
References (55)
3 meta-analyses / systematic reviews- METAHIF-1α and VEGF Immunophenotypes as Potential Biomarkers in the Prognosis and Evaluation of Treatment Efficacy of Atherosclerosis: A Systematic Review of the Literature. — Frontiers in bioscience (Landmark edition) 2025 · PMID 39862086
- METAPersonalized Nutrition Biomarkers and Dietary Strategies for Atherosclerosis Risk Management: A Systematic Review. — Nutrients 2025 · PMID 40944193
- METAA systematic review of TMAO, microRNAs, and the oral/gut microbiomes in atherosclerosis and myocardial infarction: mechanistic insights and translational opportunities. — Journal of translational medicine 2025 · PMID 41225505
- Exercised gut microbiota improves vascular and metabolic abnormalities in sedentary diabetic mice through gut‒vascular connection. — Journal of sport and health science 2025 · PMID 39827989
- Atheroprotective roles of exercise-regulated microRNAs. — Atherosclerosis 2025 · PMID 40367725
- MicroRNA regulatory dynamic, emerging diagnostic and therapeutic frontier in atherosclerosis. — Microvascular research 2025 · PMID 40368159
- Inflammatory Macrophage-Targeted Atherosclerosis Treatment by miRNA-Delivered, MRI-Visible, and Anti-Inflammatory Nanomedicine. — ACS nano 2025 · PMID 40433973
- MicroRNA-26b-/- augments atherosclerosis, while mimic-loaded nanoparticles reduce atherogenesis. — Cardiovascular research 2025 · PMID 41223017
- Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling. — Life sciences 2024 · PMID 38237765
- microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression. — Cellular signalling 2024 · PMID 38471617
- MiRNA-132/212 encapsulated by adipose tissue-derived exosomes worsen atherosclerosis progression. — Cardiovascular diabetology 2024 · PMID 39252021
- Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms. — American journal of physiology. Regulatory, integrative and comparative physiology 2023 · PMID 37335014
- Long-Term Impacts of Preeclampsia on the Cardiovascular System of Mother and Offspring. — Hypertension (Dallas, Tex. : 1979) 2023 · PMID 37377011
- MicroRNAs Regulate Function in Atherosclerosis and Clinical Implications. — Oxidative medicine and cellular longevity 2023 · PMID 37675243
- Selected miRNA and Psoriasis-Cardiovascular Disease (CVD)-Overweight/Obesity Network-A Pilot Study. — International journal of molecular sciences 2023 · PMID 37762217
- Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice. — Science translational medicine 2023 · PMID 37910599
- CircRNA-miRNA interactions in atherogenesis. — Molecular and cellular biochemistry 2022 · PMID 35604519
- Profiling of Non-Coding Regulators and Their Targets in Epicardial Fat from Patients with Coronary Artery Disease. — International journal of molecular sciences 2022 · PMID 35628106
- Decoding microRNA drivers in atherosclerosis. — Bioscience reports 2022 · PMID 35758143
- MicroRNAs in Inflammatory Bowel Disease and Its Complications. — International journal of molecular sciences 2022 · PMID 35955886
- Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk — Journal of Periodontal Research 2022 · PMID 36482859
- Implications for MicroRNA involvement in the prognosis and treatment of atherosclerosis. — Molecular and cellular biochemistry 2021 · PMID 33389489
- MicroRNA regulation of cholesterol metabolism. — Annals of the New York Academy of Sciences 2021 · PMID 33521946
- MicroRNA-320b Modulates Cholesterol Efflux and Atherosclerosis. — Journal of atherosclerosis and thrombosis 2021 · PMID 33536383
- MicroRNA-21 Controls Circadian Regulation of Apoptosis in Atherosclerotic Lesions. — Circulation 2021 · PMID 34233454
- The Diabetes Mellitus–Atherosclerosis Connection: The Role of Lipid and Glucose Metabolism and Chronic Inflammation — International Journal of Molecular Sciences 2020 · PMID 32155866
- Macrophage Exosomes Resolve Atherosclerosis by Regulating Hematopoiesis and Inflammation via MicroRNA Cargo. — Cell reports 2020 · PMID 32668250
- Extracellular vesicle signalling in atherosclerosis. — Cellular signalling 2020 · PMID 32860954
- Interaction Between microRNA and DNA Methylation in Atherosclerosis. — DNA and cell biology 2020 · PMID 33259723
- Hepatocyte-derived extracellular vesicles promote endothelial inflammation and atherogenesis via microRNA-1. — Journal of hepatology 2019 · PMID 31568800
- Amelioration of TMAO through probiotics and its potential role in atherosclerosis. — Applied microbiology and biotechnology 2019 · PMID 31655880
- miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges — Acta Pharmacologica Sinica 2018 · PMID 29877320
- The salient role of microRNAs in atherogenesis. — Journal of molecular and cellular cardiology 2018 · PMID 30098321
- Parkinson’s Disease: Biomarkers, Treatment, and Risk Factors — Frontiers in Neuroscience 2018 · PMID 30214392
- Novel biomarkers for cardiovascular risk prediction. — PubMed 2017 · PMID 28491088
- MicroRNA let-7g alleviates atherosclerosis via the targeting of LOX-1 in vitro and in vivo. — International journal of molecular medicine 2017 · PMID 28535009
- MicroRNA-214-3p: A link between autophagy and endothelial cell dysfunction in atherosclerosis. — Acta physiologica (Oxford, England) 2017 · PMID 28888077
- MicroRNA Regulation of Atherosclerosis. — Circulation research 2016 · PMID 26892968
- MicroRNA-30c Mimic Mitigates Hypercholesterolemia and Atherosclerosis in Mice. — The Journal of biological chemistry 2016 · PMID 27365390
- Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016. — BMC health services research 2016 · PMID 27409075
- microRNA profiling in atherosclerosis, diabetes, and migraine. — Annals of medicine 2016 · PMID 27560467
- MicroRNA-181b Controls Atherosclerosis and Aneurysms Through Regulation of TIMP-3 and Elastin. — Circulation research 2016 · PMID 27756793
- Use of microRNAs as Anti-Atherosclerosis. — Mini reviews in medicinal chemistry 2015 · PMID 25807944
- MicroRNAs in cardiovascular disease: an introduction for clinicians — Heart 2015 · PMID 25814653
- Circulating microRNAs in Sera Correlate with Soluble Biomarkers of Immune Activation but Do Not Predict Mortality in ART Treated Individuals with HIV-1 Infection: A Case Control Study — PLoS ONE 2015 · PMID 26465293
- Functions of microRNA-33a/b and microRNA therapeutics. — Journal of cardiology 2015 · PMID 26645139
- MicroRNA-24 regulates macrophage behavior and retards atherosclerosis. — Arteriosclerosis, thrombosis, and vascular biology 2014 · PMID 24990232
- MicroRNA-specific regulatory mechanisms in atherosclerosis. — Journal of molecular and cellular cardiology 2014 · PMID 25450610
- MicroRNA-126, -145, and -155: a therapeutic triad in atherosclerosis? — Arteriosclerosis, thrombosis, and vascular biology 2013 · PMID 23324496
- Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice. — Circulation research 2013 · PMID 24255059
- The magic and mystery of microRNA-27 in atherosclerosis. — Atherosclerosis 2012 · PMID 22307089
- MicroRNA regulation of lipid metabolism. — Metabolism: clinical and experimental 2012 · PMID 22607769
- MicroRNA-33 in atherosclerosis etiology and pathophysiology. — Atherosclerosis 2012 · PMID 23261171
- Role of microRNAs in stem/progenitor cells and cardiovascular repair. — Cardiovascular research 2011 · PMID 22135162
- Circulating MicroRNAs in Patients With Coronary Artery Disease — Circulation Research 2010 · PMID 20595655
Clinical trials (6)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT02071966 | Effects of TIcaGREloR on Circulating Microparticles and Micro-RNAs in Patients With Non ST Elevation Acute Coronary Syndromes | TERMINATED | INTERVENTIONAL | Ticagrelor, Clopidogrel |
| NCT04889053 | Prospective Cohort Study of Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study) | RECRUITING | OBSERVATIONAL | |
| NCT05354193 | Analysis of microRNAs Expression in Patients Who Evolved to Vasoplegic Syndrome After On-pump Coronary Artery Bypass Surgery | COMPLETED | OBSERVATIONAL | vasoplegic syndrome |
| NCT03090763 | Role of Circulating MicroRNAs in Pathogenesis of Aneurysms of the Abdominal and Thoracic Aorta - Study "Micro AAA" | UNKNOWN | OBSERVATIONAL | PCR and sequencing |
| NCT02320539 | MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 | COMPLETED | OBSERVATIONAL | |
| NCT02213484 | Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.