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Depression

Psychosocial & Mental HealthDisease / conditionriskpartially modifiable
59
evidence score

Also known as: Current depression only, Current depressive disorder, Depressive disorder, depression (etiologic), depression (prognostic), depression preceding development of CHD, depression predicting prognosis in established CHD, depressive symptoms, major depressive

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 24meta-analyses: 20trials: 15genetic: 0MR bonus:

References (251)

31 meta-analyses / systematic reviews

Clinical trials (43)

NCTTitleStatusTypeInterventions
NCT06579950The Effects of Cool Roofs on Health, Environmental, and Economic Outcomes: a Global Multi-center Cluster-randomized Controlled TrialRECRUITINGINTERVENTIONALCool roof
NCT05644301INflammation-based Stratification for Immune-Targeted Augmentation in Major DepressiveRECRUITINGINTERVENTIONALCelecoxib, Minocyclin, Placebo
NCT05369195Cerebral Protection in Transcatheter Left Atrial Appendage Occlusion in Patients With Atrial FibrillationRECRUITINGINTERVENTIONALLAAC procedure with the use of transcatheter cerebral protection system, LAAC procedure without the use of transcatheter cerebral protection system
NCT05757791A Pilot, Phase II, Open-Label, Single-Center Study of Sodium-Glucose Cotransporter-2 Inhibitor Empagliflozin in Major Depressive DisorderRECRUITINGINTERVENTIONALEmpagliflozin
NCT07586150Personalised Pharmaco-Lifestyle Interventions for Severe Mental Illnesses Enhanced by Digital Health and Immersive TechnologiesNOT YET RECRUITINGINTERVENTIONALSemaglutide (SEMA), Exercise module, Anti-inflammatory diet module
NCT07343284Effect of a Nursing Intervention Based on Health Education on Functionality, Depression Symptoms, and Quality of Life in Patients With Ischemic Stroke: A Quasi-Experimental, Longitudinal, and Prospective Clinical TrialNOT YET RECRUITINGINTERVENTIONALHealth education Program
NCT07592117A Cluster Randomised Controlled Trial (cRCT) Evaluating the Effects of Cool Roofs on Health, Environmental and Economic Outcomes in Tavua, FijiNOT YET RECRUITINGINTERVENTIONALCool roof
NCT06834893A Cluster Randomised Controlled Trial (cRCT) Evaluating the Effects of Cool Roofs on Health, Environmental and Economic Outcomes in Colima, MexicoNOT YET RECRUITINGINTERVENTIONALCool roof
NCT07151430Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity: A Randomized Controlled TrialNOT YET RECRUITINGINTERVENTIONALService Package Group
NCT06570993A Cluster Randomised Controlled Trial (cRCT) Evaluating the Effects of Cool Roofs on Health, Environmental and Economic Outcomes in NiueCOMPLETEDINTERVENTIONALCool roof
NCT06118918Impact of Rehabilitation on Anxiety, Depression, Perceived Health Status, and Readmission Among Patients After Coronary Artery Bypass in JordanCOMPLETEDINTERVENTIONALPhase II comprehensive cardiac rehabilitation program
NCT07216729Evaluating the Effects of Lactobacillus Reuteri DSM 17938 on State and Trait Stress in Stressed AdultsCOMPLETEDINTERVENTIONALLactobacillus reuteri DSM 17938, Placebo
NCT04799899Mindfulness-Based Cognitive Therapy Delivered Via Group Videoconferencing for Acute Coronary Syndrome Patients With Depressive Symptoms: A Pilot RCTCOMPLETEDINTERVENTIONALAdapted MBCT, Cardiac Health Enhancement
NCT04410341The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients: A Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled TrialWITHDRAWNINTERVENTIONALVildagliptin 50 MG, Escitalopram 20 mg
NCT04325867Integrated Distance Management Strategy for Patients With Cardiovascular Disease (Ischaemic Coronary Artery Disease, High Blood Pressure, Heart Failure) in the Context of the COVID-19 PandemicUNKNOWNINTERVENTIONALTele-medicine platform
NCT04138407The Effects of Seated Tai Chi on Upper Limb Function, Balance Control, Depressive Symptoms, Activity of Daily Living and Quality of Life Among Subacute Stroke Survivors: A Randomized Controlled TrialUNKNOWNINTERVENTIONALseated Tai Chi, Usual rehabilitation exercise
NCT02858102Impact From Aerobic Exercise (a Program of Physical Activity) in the Metabolic Syndrome, Neurocognition and Empowerment in Individuals With Severe Mental Disorders Including Depression, Bipolar Disorder and Psychosis: a Longitudinal StudyUNKNOWNINTERVENTIONALPhysical activity program
NCT02789800Patient-Centred Innovations for Persons With Multimorbidity - QuebecCOMPLETEDINTERVENTIONALDIMAC02
NCT03072823Omega-3 Polyunsaturated Fatty Acids on Major Depressive Disorder in Patients With Cardiovascular Diseases: a Double-blind Placebo-controlled Therapeutic TrialCOMPLETEDINTERVENTIONALn-3 Polyunsaturated fatty acid, placebo
NCT02742597Patient-Centred Innovations for Persons With Multimorbidity - OntarioCOMPLETEDINTERVENTIONALTIP / IMPACT Plus Care Coordination
NCT02463110Acute Myocardial Necrosis and Depression: Antiplatelet Effect of Reuptake Inhibition of Serotonin: The ANDROS StudyTERMINATEDINTERVENTIONALSertraline, No treatment, Placebo
NCT02203552Randomized Placebo Controlled Study of Minocycline for Amelioration of Chemotherapy Induced Affective DisordersCOMPLETEDINTERVENTIONALminocycline hydrochloride, placebo, laboratory biomarker analysis
NCT02310932Improving Mental Health Through Integration With Primary Care in Rural KarnatakaCOMPLETEDINTERVENTIONALHealthy Living Intervention
NCT01800019The Canadian HIV Quit Smoking Trial: Tackling the Co-morbidities of Depression and Cardiovascular Disease in HIV+ SmokersUNKNOWNINTERVENTIONALNicotine Replacement Therapy (NRT), Varenicline, HIV Tailored Quit Smoking Counseling
NCT02709668Clinical Response and Homocysteine Reduction Using Reduced B-Vitamin Therapy in MTHFR C677T/A1298C Patients With Major Depressive Disorder : an Analysis of FindingsCOMPLETEDINTERVENTIONALEnlyte, placebo
NCT01625845Targeting Systemic Inflammation to Concurrently Treat Late-Life Depression and Reduce Coronary Artery Disease RiskCOMPLETEDINTERVENTIONALPentoxifylline, Placebo, Standard Treatment
NCT01624857Perioperative Statin for Depression in Patients Undergoing Coronary Artery Bypass SurgeryUNKNOWNINTERVENTIONALRosuvastatin, Placebo
NCT01739205Biobehavioral Bases & Management of Type 2 DiabetesCOMPLETEDINTERVENTIONALCALM-D Intervention
NCT00370058Modulation of Homocysteine-Plasma Levels by ECT - Association With Clinical Response. A Pilot Study in Patients With Major DepressionCOMPLETEDINTERVENTIONALECT treatment
NCT00214682Beyond Ageing Project: A RCT to Assess the Benefit of Improving Mental Health Literacy as Well as the Effect of Folate and B12, and Physical Activity, in Preventing Major Depression and Cognitive Decline Among Older AustraliansCOMPLETEDINTERVENTIONALFolate (400mcg) and Vitamin B12 (100 mcg), mediated physical activity promotion, Mental health literacy
NCT07444697Erectile Function After Percutaneous Coronary Intervention in Myocardial Infarction and Non-Infarction Patients: A Prospective Comparative Study.RECRUITINGOBSERVATIONAL
NCT06650436DEliriuM in STroke: the Link Between Stroke, Delirium and Long-term Cognitive ImpairmentRECRUITINGOBSERVATIONALEEG, MRI, Depression screening and neuropsychological tests
NCT06890208Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study in Germany and Italy, Third Wave (CLIMATE-III)COMPLETEDOBSERVATIONALNo intervention
NCT06473168Walking-related Mobility Assessment in Older People With MultimorbidityUNKNOWNOBSERVATIONAL
NCT06407154Chronical Illness-related Limitations of the Ability to Cope with Rising Temperatures: an Observational Study, Second Wave (CLIMATE-II)COMPLETEDOBSERVATIONAL
NCT07363980Coronary Computed Tomography Angiography In Rheumatoid Arthritis StudyENROLLING BY INVITATIONOBSERVATIONAL
NCT05961163Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study (CLIMATE)TERMINATEDOBSERVATIONAL
NCT03057691The Impact of Depression and/or Anxiety on Patients With Acute Coronary Syndrome After Percutaneous Coronary InterventionsUNKNOWNOBSERVATIONALantidepressive and anti-anxiety therapy
NCT02363114DOC Utility: Simple Screening of Depression, Obstructive Sleep Apnea and Cognitive Impairment to Identify Stroke Clinic Patients at Risk of Adverse OutcomesUNKNOWNOBSERVATIONAL
NCT02276950HeAlth-data Register sTudies of Risk and Outcomes in Cardiac Surgery (HARTROCS)ACTIVE NOT RECRUITINGOBSERVATIONALCoronary artery bypass surgery, Heart valve surgery
NCT01369030Deplin® P.L.U.S. Program (Progress Through Learning Understanding & Support)COMPLETEDOBSERVATIONALDeplin®
NCT03405675Gerontology Research Programme: Biological, Clinical, Psychosocial and Behavioural Predictors of Health Status in Prospectively Followed-up Cohorts of Elderly PersonsUNKNOWNOBSERVATIONALSLAS 1, SLAS 2
NCT02018497Essential Arterial Hypotension and Allostasis RegistryUNKNOWNOBSERVATIONAL

Genetic associations (0)

None linked.