C
Diabetic nephropathy
Renal & ElectrolyteDisease / conditionriskpartially modifiable
14
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 11.1genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Adiposity markers and risk of coronary heart disease in patients with type 2 diabetes mellitus. — Nutrition journal 2014 · PMID 25539716
Clinical trials (12)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT06501651 | A Prospective, Randomized, Controlled, Multicenter Study of Sacubitril/Valsartan in the Treatment of Patients With Mild to Moderate Essential Hypertension and Type 2 Diabetic Nephropathy: The Hyper-Save Study | NOT YET RECRUITING | INTERVENTIONAL | Sacubitril/Valsartan, Valsartan |
| NCT04027530 | Phase 4, Randomized, Placebo-controlled, Cross-over Trial to Assess the Effect of 4-week Ertugliflozin (SGLT-2 Inhibitor) Therapy on Renal Oxygenation by BOLD-MRI and Renal Oxygen Consumption by PET Using ¹¹C-acetate in T2DM Without Kidney Disease and Healthy Controls. | COMPLETED | INTERVENTIONAL | Ertugliflozin 15 mg |
| NCT04127084 | Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetes: a Prospective Interventional Study | UNKNOWN | INTERVENTIONAL | SGLT2 Inhibition |
| NCT04705506 | Effect of Gemigliptin on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Nephropathy: A Randomized Controlled Trial | COMPLETED | INTERVENTIONAL | Gemigliptin |
| NCT02442921 | The Effect of Colchicine Treatment on the Progression of Proteinuria in Patients With Diabetic Nephropathy. | UNKNOWN | INTERVENTIONAL | Colchicine, Placebo |
| NCT02065791 | A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy | COMPLETED | INTERVENTIONAL | Canagliflozin, Placebo |
| NCT02035891 | Low-dose Colchicine Intervention in Patients With Type 2 Diabetes Mellitus and Microalbuminuria: Chongqing Study | UNKNOWN | INTERVENTIONAL | colchicine 0.5mg/d, placebo 0.5mg/d |
| NCT01588795 | Renal Denervation in Patients With Diabetic Nephropathy and Persistent Proteinuria | COMPLETED | INTERVENTIONAL | Percutaneous renal denervation and TMNS, Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin |
| NCT07444203 | Transformative Research in Diabetic Nephropathy 2.0: A Proof of Principle Study of SGLT2 Inhibitors (TRIDENT 2.0) | RECRUITING | OBSERVATIONAL | Sodium-glucose cotransporter 2 inhibitors (SGLT2i), Renin-angiotensin-aldosterone system blockade, Glucagon-like peptide-1 receptor agonists (GLP 1 RA) |
| NCT07476248 | The Non-high-density Lipoprotein Cholesterol (Non-HDL-C) to High-density Lipoprotein Cholesterol (HDL-C) Ratio (NHHR) and Its Association With Occurrence of Diabetic Nephropathy in Patients With Diabetes Mellitus | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT05047471 | Healthy China - The Improvement Projects for the Screening Ability of Diabetes and Its Complications And for the Standardized Ability of Diagnosis and Treatment for Patients With Early Diabetic Nephropathy | UNKNOWN | OBSERVATIONAL | |
| NCT00498147 | Does Managed Diabetes Care Decrease Cardiovascular Complications of Diabetes? | UNKNOWN | OBSERVATIONAL | ADEC Program |
Genetic associations (0)
None linked.