B
Galectin-3
Novel & Emerging BiomarkersLab test / biomarkerrisknon modifiable
26
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 16.6meta-analyses: 9.1trials: 0genetic: 0MR bonus:
References (45)
2 meta-analyses / systematic reviews- METAAssociation of serum galectin-3 levels with mortality and cardiovascular disease outcomes in hemodialysis patients: a systematic review and dose-response meta-analysis. — International urology and nephrology 2024 · PMID 38519721
- METAGalectin-3 and risk of atrial fibrillation: A systematic review and meta-analysis. — Journal of clinical laboratory analysis 2020 · PMID 31917884
- Atrial Translocation ofExacerbates Atrial Fibrosis and Atrial Fibrillation. — Circulation 2025 · PMID 40099365
- Cardiovascular Biomarkers: Tools for Precision Diagnosis and Prognosis. — International journal of molecular sciences 2025 · PMID 40244022
- AI-driven discovery of brain-penetrant Galectin-3 inhibitors for Alzheimer's disease therapy. — Pharmacological research 2025 · PMID 40543907
- Galectin-3: Integrator of Signaling via Hexosamine Flux. — Biomolecules 2025 · PMID 40723900
- Galectin-3 gene deletion alters lipid profile in healthy and cardiomyopathy mouse hearts. — Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 · PMID 40759316
- Galectin-3 and kidney function in type 2 diabetes treated with dapagliflozin: Analysis from DECLARE-TIMI 58. — ESC heart failure 2025 · PMID 40952180
- Cigarette smoke-induced galectin-3 as a diagnostic biomarker and therapeutic target in lung tissue remodeling. — Life sciences 2024 · PMID 38237765
- Galectin-3, Metabolic Risk, and Incident Heart Failure: The ARIC Study. — Journal of the American Heart Association 2024 · PMID 38471823
- Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis. — Clinical and experimental nephrology 2024 · PMID 38643287
- Galectin-3 in chronic kidney disease. — Clinica chimica acta; international journal of clinical chemistry 2024 · PMID 38750780
- Association between sleep patterns and galectin-3 in a Chinese community population. — BMC public health 2024 · PMID 38755574
- Galectin-3, Galectin-9, and Interleukin-18 Are Associated with Monocyte/Macrophage Activation and Turnover More so than Simian Immunodeficiency Virus-Associated Cardiac Pathology or Encephalitis. — AIDS research and human retroviruses 2024 · PMID 38787309
- The detrimental role of galectin-3 and endoplasmic reticulum stress in the cardiac consequences of myocardial ischemia in the context of obesity. — FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 · PMID 38989572
- Unlocking the role of Galectin-3: Implications for sleep disorders and health. — Sleep medicine 2024 · PMID 39288581
- Central role of Galectin-3 at the cross-roads of cardiac inflammation and fibrosis: Implications for heart failure and transplantation. — Cytokine & growth factor reviews 2024 · PMID 39482190
- Role of galectin-3 in vascular calcification. — Glycoconjugate journal 2023 · PMID 36807052
- Galectin-3 and HFpEF: Clarifying an Emerging Relationship. — Current cardiology reviews 2023 · PMID 36959138
- The Role of Galectin-3 in Heart Failure-The Diagnostic, Prognostic and Therapeutic Potential-Where Do We Stand? — International journal of molecular sciences 2023 · PMID 37685918
- Insights into the Role of Galectin-3 as a Diagnostic and Prognostic Biomarker of Atrial Fibrillation. — Disease markers 2023 · PMID 37849915
- Sex-specific role of galectin-3 in aortic stenosis. — Biology of sex differences 2023 · PMID 37875993
- Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling. — Acta physiologica (Oxford, England) 2022 · PMID 34995420
- Galectin 3 enhances platelet aggregation and thrombosis via Dectin-1 activation: a translational study. — European heart journal 2022 · PMID 35165707
- A Scoping Review of Galectin-3 as a Biomarker of Cardiovascular Diseases in Pediatric Populations. — International journal of environmental research and public health 2022 · PMID 35410028
- Obesity, Galectin-3, and Incident Heart Failure: The ARIC Study. — Journal of the American Heart Association 2022 · PMID 35491999
- Galectin-3-centered paracrine network mediates cardiac inflammation and fibrosis upon β-adrenergic insult. — Science China. Life sciences 2022 · PMID 36449214
- Exercise modulation in inflammation and metabolic hormonal disorders of COVID-19 to decrease risk factors in coronary heart disease. — Hormone molecular biology and clinical investigation 2022 · PMID 36560914
- ST2 and galectin-3 as novel biomarkers for the prediction of future cardiovascular disease risk in preeclampsia. — Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2021 · PMID 34930081
- The Diagnostic and Therapeutic Potential of Galectin-3 in Cardiovascular Diseases. — Biomolecules 2021 · PMID 35053194
- Galectin-3 and Cardiovascular Biomarkers Reflect Adaptation Response to Scuba Diving. — International journal of sports medicine 2020 · PMID 31975358
- Galectin-3 Is a Potential Mediator for Atherosclerosis. — Journal of immunology research 2020 · PMID 32149158
- The role of galectin-3 in heart failure and cardiovascular disease. — Clinical and experimental pharmacology & physiology 2019 · PMID 30372548
- Association of plasma-soluble ST2 and galectin-3 with cardiovascular events and mortality following cardiac surgery. — American heart journal 2019 · PMID 31911262
- Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update. — Theranostics 2018 · PMID 29344292
- Galectin-3 and risk of cardiovascular events and all-cause mortality in type 2 diabetes. — Diabetes/metabolism research and reviews 2018 · PMID 30378236
- Novel biomarkers of cardiovascular disease: Applications in clinical practice — Critical Reviews in Clinical Laboratory Sciences 2018 · PMID 30457415
- Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes. — Journal of the American College of Cardiology 2018 · PMID 30573026
- Galectin-3 in acute coronary syndrome. — Clinical biochemistry 2017 · PMID 28456545
- Novel biomarkers for cardiovascular risk prediction. — PubMed 2017 · PMID 28491088
- Serial galectin-3 and future cardiovascular disease in the general population. — Heart (British Cardiac Society) 2016 · PMID 27084804
- The Role of Galectin-3 in the Kidneys. — International journal of molecular sciences 2016 · PMID 27089335
- Galectin-3, Cardiac Function, and Fibrosis. — The American journal of pathology 2016 · PMID 27461364
- Biomarkers and heart disease. — European review for medical and pharmacological sciences 2014 · PMID 25339488
- Galectin-3 increase in endurance athletes. — European journal of preventive cardiology 2013 · PMID 23723328
Clinical trials (0)
None linked.
Genetic associations (0)
None linked.