C
Genetic predisposition to coronary heart disease
Genetic & Family HistoryGenetic / heritablerisknon modifiable
14
evidence score
Also known as: Genetics, genetic factors for coronary heart disease, shared genetic determinants
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 4.8meta-analyses: 0trials: 9genetic: 0MR bonus:
References (2)
0 meta-analyses / systematic reviews- Genomic prediction of coronary heart disease. — European heart journal 2016 · PMID 27655226
- Coronary heart disease and depression: a review of recent mechanistic research. — Canadian journal of psychiatry. Revue canadienne de psychiatrie 2006 · PMID 17168248
Clinical trials (7)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT02462421 | Pharmacogenetics of Sodium-dependent Glucose Transporter-2 (SGLT2) Inhibitors | TERMINATED | INTERVENTIONAL | Canagliflozin |
| NCT03347435 | Pharmacogenetics of Clopidogrel in Acute Coronary Syndromes | TERMINATED | INTERVENTIONAL | genetic tests for CYP2C19*2, CYP2C19*17 and ABCB1 3435, clinical algorithm |
| NCT01864824 | Air Pollution, Epigenetics and Cardiovascular Health: A Human Intervention Trial | COMPLETED | INTERVENTIONAL | methyl donor, Placebo |
| NCT05515653 | Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian Population | UNKNOWN | OBSERVATIONAL | Exposure to genetics (polygenic) |
| NCT03752515 | A Chinese Registry to Determine the Genetics Risk Factors and Serumal Biomarkers for Acute Coronary Syndrome | UNKNOWN | OBSERVATIONAL | |
| NCT02131610 | Epigenetics Modifications and Subclinical Atherosclerosis in Obstructive Sleep Apnea: The EPIOSA Study | UNKNOWN | OBSERVATIONAL | |
| NCT00615121 | Genetics of Peripheral Artery Disease | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.