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Hypertension

Blood Pressure & HemodynamicsDisease / conditionriskmodifiable
65
evidence score

Also known as: Arterial hypertension, Blood pressure, Blood pressure elevation, Elevated blood pressure, altered blood pressure, arterial hypertension, blood pressure, blood pressure / hypertension, chronic hypertension, diurnal hypertension, elevated blood pressure, essential hypertension

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 30meta-analyses: 20trials: 15genetic: 0MR bonus:

References (1119)

70 meta-analyses / systematic reviews

Clinical trials (395)

showing top 60
NCTTitleStatusTypeInterventions
NCT05826925Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of PregnancyRECRUITINGINTERVENTIONALDecision aid
NCT07460154A Structured Health Assessment in Frequent COPD Exacerbators: To Optimise Management, Identify Comorbidities and Prevent Oral Corticosteroid Related HarmRECRUITINGINTERVENTIONALSputum sample, Venepuncture, Lung function test
NCT07547345Live Healthy Chicago - Community PilotRECRUITINGINTERVENTIONALCommunity-Based Multidisciplinary Hypertension Management Program
NCT07588256New Taipei City 888 Digital Medical AI Platform for the Prevention and Treatment of the Three Highs (Hypertension, Hyperglycemia, Hyperlipidemia) and Cardio-Renal-Vascular Diseases: Validation and Implementation Through Large-Scale Cluster Randomized Clinical Trials: T-888-DIGICARE-DREAMRECRUITINGINTERVENTIONALInteractive digital modules, Antihypertensive Medication Management
NCT07098065Health Warnings and Counseling at Primary Health Care Centers for Smoking Cessation and NCD Prevention: A Randomized Controlled Trial in Bangladesh and PakistanRECRUITINGINTERVENTIONALGraphical health warnings, Graphical health warnings plus pharmacist-led counselling, Routine pharmacy services (no intervention)
NCT07279259Thrombolysis in Early Acute Ischemic Stroke Trial-Blood Pressure Management, EAST-BPRECRUITINGINTERVENTIONALAdjusted BP management group, Usual BP management group
NCT06952348HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking in Individuals With Increased Cardiometabolic Risk - The HYPERWALK Randomized Controlled TrialRECRUITINGINTERVENTIONALStair and brisk walking combined, Brisk walking, Standard care
NCT06966258Inspire HER: Inspiring the Heart and Emotions for Radical HealthRECRUITINGINTERVENTIONALInspire HER Intervention
NCT06891911Groceries for Residents of Southeastern USA to Stop HypertensionRECRUITINGINTERVENTIONALDietitian-Assisted DASH groceries, Self-directed shopping
NCT06962488Clinical Implementation of Blood Pressure Polygenic Risk ScoreRECRUITINGINTERVENTIONALRegular Care, SBP PRS Dissemination
NCT07023003Postpartum Evaluation of Antihypertensives for Control of Hypertension: A Randomized Controlled Equivalence StudyRECRUITINGINTERVENTIONALEnalapril 10mg QD, Nifedipine 30mg XL BID
NCT07045623Comparison of Intensive Versus Standard Care & Education for Dyslipidemia in Hypertension and Diabetes PatientsRECRUITINGINTERVENTIONALcentralized management and education group
NCT07482020A Randomized Controlled Trial of SGLT2 Inhibitors to Improve Left Atrial Function in Patients With Paroxysmal Atrial Fibrillation and Comorbid Hypertension and Abnormal Glucose MetabolismRECRUITINGINTERVENTIONALSGLT-2 inhibitors, Placebo
NCT07614659Uppsala Self-Screening of Cardiovascular Health: A Randomized Controlled Trial of Home-Based Multimodal Cardiovascular Screening Versus Usual Care in Middle-Aged and Older AdultsRECRUITINGINTERVENTIONALHome-based multimodal cardiovascular screening
NCT06693934Jockey Club Precision Prevention Programme on Young Onset DiabetesRECRUITINGINTERVENTIONALRisk assessment with biogenetic and clinical test to predict diabetes risk, Oral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factors, Medication
NCT06677970Outcome in Patients Treated With Endovascular Thrombectomy - optIMAL Blood Pressure Control 2 (OPTIMAL-BP 2)RECRUITINGINTERVENTIONALBP lowering drugs (nicardipine, labetalol, urapidil), BP raising drug (phenylephrine) or BP lowering drugs (nicardipine, labetalol, urapidil)
NCT06352632A Multi-faCtorial, mulTi-arm, Multi-staGe, Randomised, gLOBal Adaptive pLatform Trial for Stroke (ACT-GLOBAL)RECRUITINGINTERVENTIONALStandard-dose intravenous tenecteplase, Low-dose intravenous tenecteplase, No intravenous tenecteplase
NCT06523465A Prospective, Multi-center, Randomized Trial to Compare Statin Combined with CCB to MRA Combined with CCB in Primary Aldosteronism TreatmentRECRUITINGINTERVENTIONALSimvastatin combined with Amlodipine besylate, Simvastatin combined with Spironolactone and Amlodipine besylate., Amlodipine besylate combined Spironolactone
NCT06579950The Effects of Cool Roofs on Health, Environmental, and Economic Outcomes: a Global Multi-center Cluster-randomized Controlled TrialRECRUITINGINTERVENTIONALCool roof
NCT04974151Comparative Efficacy of Amlodipine Folic Acid vs. Amlodipine on the Risk of First Ischemic Stroke Among Participants With Hypertension and MTHFR 677 TT Genotype: A Multi-center, Randomized, Double-blind, Triple-dummy, Controlled Clinical TrialRECRUITINGINTERVENTIONALAmlodipine besylate, Amlodipine besylate And Folic Acid, 5-methyltetrahydrofolate (5-MTHF)
NCT04974138Comparative Efficacy of Amlodipine Folic Acid vs. Amlodipine on the Risk of First Ischemic Stroke Among Participants With H-type Hypertension and MTHFR 677 CC/CT Genotype: A Multi-center, Randomized, Double-blind, Double-dummy, Controlled Clinical TrialRECRUITINGINTERVENTIONALAmlodipine besylate, Amlodipine besylate and folic acid, Amlodipine placebos
NCT07447362Effect of a Structured Clinical and Pharmacological Management Strategy on Cardiovascular Risk Factors in Adult Patients in Routine Clinical Practice: A Pseudo-Experimental Before-and-After StudyRECRUITINGINTERVENTIONALStructured Cardiovascular Risk Management
NCT06538454Acute and Chronic Effects of Resistance Training Intensity on Cardiovascular Parameters of Postmenopausal Women With Systemic Arterial HypertensionRECRUITINGINTERVENTIONALResistance training
NCT06322056Exploring Approaches With Lower Targets of Blood Pressure and Lipid for Improving Renal Outcome in Advanced Chronic Kidney DiseaseRECRUITINGINTERVENTIONALIntensive control of SBP and intensive control of LDL-C, Intensive control of SBP and standard control of LDL-C, Standard control of SBP and intensive control of LDL-C
NCT04647292European Blood Pressure Intensive Control After Stroke - Pilot TrialRECRUITINGINTERVENTIONALanti-hypertensive, home blood pressure measurement, telemonitoring and medication titration, Standard of Care Blood Pressure Management with Antihypertensives
NCT06775028AFFIRMO - Atrial Fibrillation Integrated Approach in Frail, Multimorbid and Polymedicated Older PeopleRECRUITINGINTERVENTIONALiABC platform use
NCT06062394Reducing Atherosclerotic Cardiovascular Disease (ASCVD) Through a Comprehensive Heart Disease Prevention Program (HDPP)RECRUITINGINTERVENTIONALPenn Med Healthy Heart Program
NCT05999851Multiparametric Assessment of Maternal Vascular Function as a New Diagnostic and Prognostic Tool for Hypertensive Disorders of Pregnancy and Preeclampsia - EDIPE StudyRECRUITINGINTERVENTIONALArterial applanation tonometry, In vivo endothelial glycocalyx measurement, Serum markers of angiogenesis and endothelial dysfunction
NCT06055036Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health InterventionRECRUITINGINTERVENTIONALBlack Impact Intervention
NCT05533645Development and Validation of a Food Frequency Questionnaire to Assess Sodium Intake in Hospitalized Patients or in Medical ConsultationRECRUITINGINTERVENTIONALQuestionnaire
NCT05473520Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis: A Phase III Randomized Control Trial (Doxy-TB)RECRUITINGINTERVENTIONALDoxycycline, Placebo
NCT055908713D Cardiac Electrophysiological Mapping System on Renal Artery Radiofrequency Ablation System for Hypertension: a Prospective, Multicenter, Randomized Controlled TrialRECRUITINGINTERVENTIONALFlashPoint renal denervation system, Sham
NCT05252208Is Stretching Superior to Aerobic Training for Reducing Blood Pressure?RECRUITINGINTERVENTIONALStretching exercise, Walking exercise
NCT04911491Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure in Midlife and Older Adults With Chronic Kidney DiseaseRECRUITINGINTERVENTIONALIMST, Sham Training
NCT03710902Empowerment and Mobile Technology in the Control of Cardiovascular Risk Factors in Patients With Ischemic StrokeRECRUITINGINTERVENTIONALECG monitoring for 3 weeks, Self-monitoring of BP and self-titration of antihypertensive medication
NCT07695220Efficacy and Safety of an Early Intensive Blood Pressure-Lowering Strategy Using Remifentanil and Dexmedetomidine in Patients With Spontaneous Intracerebral Hemorrhage: A Multicenter, Prospective, Superiority, Randomized Controlled TrialNOT YET RECRUITINGINTERVENTIONALRemifentanil and Dexmedetomidine, Guideline standard care
NCT07664787Safety and Efficacy of Six-Channel Radiofrequency Ablation System for Renal Denervation in Patients With Untreated Grade I Hypertension: a Pilot StudyNOT YET RECRUITINGINTERVENTIONALSix-channel RF Renal Denervation System, Parallel controln with sham operation(there is no rade and/or generic name,It is a blank control sham operation)
NCT07654231Reducing Inflammation to Improve Vascular and Bone Outcomes With Low-dose Colchicine in CKD: A Pilot Randomized Open-Label Trial (RESOLVE-CKD Trial)NOT YET RECRUITINGINTERVENTIONALLow-dose Colchicine at 0.5mg daily, Usual Care
NCT07628283A Prospective, Open-Label, Cluster Randomized Controlled Trial to Evaluate the Efficacy of a Rural Doctor-Led, Telemedicine-Supported Integrated Care Model for Reducing Cardiovascular and Cerebrovascular Events in Elderly Adults at High Risk of Stroke in ChinaNOT YET RECRUITINGINTERVENTIONALEnhanced Usual Stroke Care, Digital Health Platform-Supported Integrated Stroke Management
NCT06798649Effect of Visual Presentation of Atherosclerotic Plaque on Modification of Arterial Hypertension One Year Postpartum in Women With a History of Adverse Pregnancy Outcomes, and Risk Customization With AI Prediction Algorithms: GESTA-COR Trial, a Prospective Randomised Clinical TrialNOT YET RECRUITINGINTERVENTIONALThe intervention in the GESTACOR study involves providing detailed feedback from vascular imaging to women who have experienced adverse pregnancy outcomes (APOs).
NCT07620808Medically Tailored Groceries for Cardiovascular HealthENROLLING BY INVITATIONINTERVENTIONALMedically Tailored Groceries
NCT07592117A Cluster Randomised Controlled Trial (cRCT) Evaluating the Effects of Cool Roofs on Health, Environmental and Economic Outcomes in Tavua, FijiNOT YET RECRUITINGINTERVENTIONALCool roof
NCT07589452Impact of Allometric Pacing Rate on Ventricular Diastolic Function and Cerebral Blood Flow in Hypertensive Patients With Sinus Node DysfunctionNOT YET RECRUITINGINTERVENTIONALPersonalized lower rate pacing, Standard lower rate pacing
NCT07206303The Effects of Bifidobacterium-based Probiotics in Reducing Blood Pressure in Middle-aged Chinese With Hypertension: a Single-term Feasibility Pilot StudyNOT YET RECRUITINGINTERVENTIONALBifidobacterium probiotics supplementation
NCT06834893A Cluster Randomised Controlled Trial (cRCT) Evaluating the Effects of Cool Roofs on Health, Environmental and Economic Outcomes in Colima, MexicoNOT YET RECRUITINGINTERVENTIONALCool roof
NCT07386535Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke PreventionACTIVE NOT RECRUITINGINTERVENTIONALMusic4Health Intervention
NCT07368608A Randomized, Double-blind, Placebo-controlled Phase I/II Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Subcutaneous BEBT-701 in Patients With Mild to Moderate Hypertension and Elevated LDL-CNOT YET RECRUITINGINTERVENTIONALBEBT-701 Injection, BEBT-701 Injection Placebo（0.9% Sodium Chloride Injection）
NCT07261098A Prospective Study of the Efficacy and Safety of Angiotensin Receptor-neprilysin Inhibitor in Patients With Advanced Lung Cancer and Concurrent HypertensionNOT YET RECRUITINGINTERVENTIONALARNI, Anti-hypertensive drugs except ARNI
NCT07151430Development and Validation of a Comprehensive Management Service Package for Older Adults With Multimorbidity: A Randomized Controlled TrialNOT YET RECRUITINGINTERVENTIONALService Package Group
NCT07255677Effect of Stretching Exercises Versus Aerobic Exercises on PreeclampsiaNOT YET RECRUITINGINTERVENTIONALStretching exercises program, Aerobic exercises program, Antihypertensive drugs
NCT07209527Evaluation of Truway Health-Sourced Portable Diagnostic Devices for Early Detection of Chronic Conditions in Outpatient Primary Care Settings: A Prospective Interventional StudyENROLLING BY INVITATIONINTERVENTIONALTruway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
NCT07124728Impact of Syntrillo's Telehealth Service on Stroke Risk Factor Reduction in At-risk PatientsNOT YET RECRUITINGINTERVENTIONALTechnology-enabled Telehealth Care Plan, Blood Pressure Monitoring Device, Tenovi Smart Pillbox
NCT06960057Exploring Virtual Reality as a Clinical Tool for Blood Pressure Reduction and Assessment of White Coat Hypertension/Effect: A Pre- and Post-Intervention Study With ABPM ValidationCOMPLETEDINTERVENTIONALVirtual Reality Exposure
NCT06379750STOP NCDs: Scaling Up Evidence-based Health System Interventions Through the Use of Sustainable Healthcare Financing and Digital TechnOlogy Platforms to Improve Non- Communicable Disease Prevention and Control in TanzaniaNOT YET RECRUITINGINTERVENTIONALNurse-delivered care using WelTel check-ins and BCC SMS, Community-based peer-support model
NCT06780865Protection of Renal Function by Antihypertensive Treatment in Patients with Chronic Kidney Disease and Isolated Nighttime HypertensionNOT YET RECRUITINGINTERVENTIONALAntihypertensive treatment with Arotinolol or Amlodipine or Clonidine, Placebo-controlled group
NCT07303556Improving the Diagnosis and Treatment of Cardiovascular Diseases in Kazakhstan by Introducing Correction of Metabolism With Glucagon-like Peptide 1 (GLP-1) DrugsACTIVE NOT RECRUITINGINTERVENTIONALTirzepatide (Mounjaro), dapagliflozin, empagliflozin, metformin
NCT06692764A Phase II Study to Assess the Effect of AZD0780 on Ambulatory Blood Pressure in Participants With Atherosclerotic Cardiovascular Disease or Risk Equivalents and Elevated Low-Density Lipoprotein CholesterolCOMPLETEDINTERVENTIONALPlacebo, AZD0780
NCT06819839Impact of a Community Health Worker Care Model to Reduce Cardiovascular Disease Risk Among Conflict-affected Populations in Eastern Myanmar: a Cluster Randomized Controlled Trial (cRCT)COMPLETEDINTERVENTIONALVillage Health Worker (VHW) Care Model
NCT05993481The Effect of More Frequent Noninvasive Blood Pressure Measurement on the Detection of Intraoperative HypotensionENROLLING BY INVITATIONINTERVENTIONALBlood Pressure Measurement
NCT06644339Remote Multichannel Monitoring of Patients With Chronic DIseAses Using Speech technoLogies Based On Artificial intelliGenceNOT YET RECRUITINGINTERVENTIONALVoice assistant

Genetic associations (0)

None linked.