C
IGF-1/Growth hormone axis
Novel & Emerging BiomarkersLab test / biomarkermixedpartially modifiable
13
evidence score
Also known as: Growth hormone/IGF-1, igf-1, insulin-like growth factor
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 10meta-analyses: 0trials: 3genetic: 0MR bonus:
References (9)
0 meta-analyses / systematic reviews- Comparative Effects of Different Exercise Types on Cardiovascular Health and Executive Function in Sedentary Young Individuals. — Medicine and science in sports and exercise 2025 · PMID 39780353
- Improved prediction and risk stratification of major adverse cardiovascular events using an explainable machine learning approach combining plasma biomarkers and traditional risk factors. — Cardiovascular diabetology 2025 · PMID 40176039
- A validated multivariable machine learning model to predict cardio-kidney risk in diabetic kidney disease. — Cardiovascular diabetology 2025 · PMID 40375260
- Large-Scale Plasma Proteomics Profiles for Predicting Ischemic Stroke Risk in the General Population. — Stroke 2024 · PMID 39704077
- Insulin-like growth factor 1 reduces coronary atherosclerosis in pigs with familial hypercholesterolemia. — JCI insight 2023 · PMID 36602878
- Endothelial IGF-1 Receptor Signalling in Diabetes and Insulin Resistance. — Trends in endocrinology and metabolism: TEM 2015 · PMID 26712712
- Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury — Critical Care 2013 · PMID 23388612
- Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations — Nutrition & Metabolism 2012 · PMID 23113919
- Insulin-Like Growth Factor (IGF) I, -II, and IGF Binding Protein-3 and Risk of Ischemic Stroke — The Journal of Clinical Endocrinology & Metabolism 2005 · PMID 16131586
Clinical trials (1)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT04710186 | The Influence of Androgen Receptor, Insulin Like Growth Factor 1 Receptor, and Insulin Receptor in Male Patients With Peripheral Artery Disease | UNKNOWN | OBSERVATIONAL | arterial reconstructive open surgery |
Genetic associations (0)
None linked.