D
IL6R genetic variant (Asp358Ala)
Genetic & Family HistoryGenetic / heritableprotectivenon modifiable
3
evidence score
Also known as: IL-6 receptor genetic variant (impaired signaling), IL-6 receptor variant impairing classic IL-6 signaling
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 3meta-analyses: 0trials: 0genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Inflammation and atherosclerosis: a review of the role of interleukin-6 in the development of atherosclerosis and the potential for targeted drug therapy. — Cardiology in review 2014 · PMID 24618929
Clinical trials (0)
None linked.
Genetic associations (0)
None linked.