A
Inflammatory bowel disease
Inflammatory & ImmuneDisease / conditionrisknon modifiable
45
evidence score
Also known as: crohn, inflammatory bowel disease (IBD), inflammatory bowel diseases
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 18.3meta-analyses: 19.3trials: 7genetic: 0MR bonus:
References (66)
7 meta-analyses / systematic reviews- METACardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis. — Annals of medicine 2025 · PMID 39838595
- METAAssociation between inflammatory bowel disease, current therapies, and cardiovascular events: a review and meta-analysis of data from 2.2 million individuals. — Journal of Crohn's & colitis 2025 · PMID 40333172
- METAInflammatory bowel disease and associated cardiovascular disease outcomes: A systematic review. — Medicine 2023 · PMID 36820570
- METAInflammatory bowel disease and cardiovascular disease incidence and mortality: A meta-analysis. — European journal of preventive cardiology 2018 · PMID 30074405
- METAAssociation of Psoriasis With Inflammatory Bowel Disease: A Systematic Review and Meta-analysis. — JAMA dermatology 2018 · PMID 30422277
- METASubclinical Atherosclerosis in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis. — Angiology 2016 · PMID 27252243
- METACarotid intima-media thickness in patients with inflammatory bowel disease: a systematic review. — Angiology 2013 · PMID 23423851
- Ginseng exosomes modulate M1/M2 polarisation by activating autophagy and target IKK/IкB/NF-кB to alleviate inflammatory bowel disease. — Journal of nanobiotechnology 2025 · PMID 40065319
- Prostaglandins and Inflammatory Bowel Disease: From Mechanism to Clinic. — Inflammatory bowel diseases 2025 · PMID 40556439
- Lipid-lowering drug targets influence inflammatory bowel disease through gut microbiota and inflammatory cytokines. — Journal of lipid research 2025 · PMID 40769382
- Multi-omics integration reveals functional signatures of gut microbiome in atherosclerosis. — Gut microbes 2025 · PMID 40785047
- Akkermansia muciniphila: A key player in gut microbiota-based disease modulation. — Microbiological research 2025 · PMID 40845731
- Human breast milk and its impact on inflammatory bowel disease. — Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 2025 · PMID 40903241
- The interaction between inflammatory bowel disease and cardiovascular disease: what we know. — Future cardiology 2025 · PMID 41208313
- Atherosclerotic cardiovascular disease and inflammatory bowel disease: epidemiology, pathogenesis and risk assessment. — Best practice & research. Clinical gastroenterology 2025 · PMID 41350098
- Cardiovascular Manifestations in Inflammatory Bowel Disease. — Current cardiology reviews 2024 · PMID 38018203
- Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis. — EBioMedicine 2024 · PMID 38583262
- The mediating effect of blood biomarkers in the associations between inflammatory bowel disease and incident psychiatric disorders: a prospective cohort study. — International journal of surgery (London, England) 2024 · PMID 38896866
- Exploring the Link Between Genetic Predictors of Cardiovascular Disease and Psoriasis. — JAMA cardiology 2024 · PMID 39292496
- Psoriasis management tree based on comorbidity. — International journal of dermatology 2024 · PMID 39420121
- Dietary Antioxidant Capacity, Genetic Susceptibility and Polymorphism, and Inflammatory Bowel Disease Risk in a Prospective Cohort. — Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2024 · PMID 39510220
- Mechanistic insight: Linking cardiovascular complications of inflammatory bowel disease. — Trends in cardiovascular medicine 2023 · PMID 36702388
- The oft-overlooked cardiovascular complications of inflammatory bowel disease. — Expert review of clinical immunology 2023 · PMID 36722283
- Anthocyanins-gut microbiota-health axis: A review. — Critical reviews in food science and nutrition 2023 · PMID 36927343
- Atherosclerotic Cardiovascular Disease in Inflammatory Bowel Disease: The Role of Chronic Inflammation and Platelet Aggregation. — Medicina (Kaunas, Lithuania) 2023 · PMID 36984554
- Inflammatory bowel disease and atrial fibrillation: a contemporary overview. — European journal of gastroenterology & hepatology 2023 · PMID 37161981
- Cardiovascular manifestations of inflammatory bowel diseases and the underlying pathogenic mechanisms. — American journal of physiology. Regulatory, integrative and comparative physiology 2023 · PMID 37335014
- Gut microbiota, intestinal permeability, and systemic inflammation: a narrative review — Internal and Emergency Medicine 2023 · PMID 37505311
- Coronary artery calcium scoring for cardiovascular risk assessment in patients with inflammatory bowel disease. — American heart journal 2023 · PMID 37634654
- Circular RNAs in inflammatory bowel disease. — Frontiers in immunology 2023 · PMID 38187401
- MicroRNAs in Inflammatory Bowel Disease and Its Complications. — International journal of molecular sciences 2022 · PMID 35955886
- Inflammatory Bowel Disease and Cardiovascular Diseases. — The American journal of medicine 2022 · PMID 36058305
- Human gut microbiota in health and disease: Unveiling the relationship — Frontiers in Microbiology 2022 · PMID 36225386
- Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses — Frontiers in Pharmacology 2022 · PMID 36353491
- Cardiovascular Risk Assessment and Impact of Medications on Cardiovascular Disease in Inflammatory Bowel Disease. — Inflammatory bowel diseases 2021 · PMID 32978937
- Alterations of the Skin and Gut Microbiome in Psoriasis and Psoriatic Arthritis — International Journal of Molecular Sciences 2021 · PMID 33924414
- NSAIDs, gastrointestinal toxicity and inflammatory bowel disease. — Gastroenterologia y hepatologia 2021 · PMID 34157367
- What Links an Increased Cardiovascular Risk and Inflammatory Bowel Disease? A Narrative Review. — Nutrients 2021 · PMID 34444821
- Metformin for Cardiovascular Protection, Inflammatory Bowel Disease, Osteoporosis, Periodontitis, Polycystic Ovarian Syndrome, Neurodegeneration, Cancer, Inflammation and Senescence: What Is Next? — ACS Pharmacology & Translational Science 2021 · PMID 34927008
- [Atherosclerosis and cardiovascular risk in patients with inflammatory bowel disease]. — Terapevticheskii arkhiv 2021 · PMID 36286684
- The risk of cardiovascular complications in inflammatory bowel disease. — Clinical and experimental medicine 2020 · PMID 32785793
- The Gut Microbiota and Inflammation: An Overview — International Journal of Environmental Research and Public Health 2020 · PMID 33086688
- Inflammatory bowel disease and the risk of cardiovascular diseases. — Gastroenterologia y hepatologia 2020 · PMID 33223261
- Inflammatory Bowel Disease and Atherosclerotic Cardiovascular Disease: JACC Review Topic of the Week. — Journal of the American College of Cardiology 2020 · PMID 33303079
- Management of psoriasis as a systemic disease: what is the evidence? — The British journal of dermatology 2019 · PMID 31225638
- Gut Microbiome: Profound Implications for Diet and Disease — Nutrients 2019 · PMID 31315227
- The Human Gut Microbiome – A Potential Controller of Wellness and Disease — Frontiers in Microbiology 2018 · PMID 30154767
- Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease. — Cell 2018 · PMID 30270042
- Overview of Link Between Inflammatory Bowel Disease and Cardiovascular Disease. — Cardiology in review 2018 · PMID 30277903
- Control of Inflammatory Bowel Disease and Colorectal Cancer by Synthetic Vitamin D Receptor Ligands. — Current medicinal chemistry 2017 · PMID 27915991
- Nanomedicines for dysfunctional macrophage-associated diseases. — Journal of controlled release : official journal of the Controlled Release Society 2017 · PMID 28057522
- Influence of diet on the gut microbiome and implications for human health — Journal of Translational Medicine 2017 · PMID 28388917
- Intestinal and Extraintestinal Cancers Associated With Inflammatory Bowel Disease. — Clinical colorectal cancer 2017 · PMID 28712945
- Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016. — BMC health services research 2016 · PMID 27409075
- Malignancies in inflammatory bowel disease. — Scandinavian journal of gastroenterology 2015 · PMID 25523559
- Cardiovascular complications in inflammatory bowel disease. — Current drug targets 2015 · PMID 25642719
- Dysbiosis of the gut microbiota in disease — Microbial Ecology in Health and Disease 2015 · PMID 25651997
- Inflammatory bowel disease and risk of coronary heart disease. — Trends in cardiovascular medicine 2015 · PMID 25912602
- Cardiovascular involvement in inflammatory bowel disease: Dangerous liaisons. — World journal of gastroenterology 2015 · PMID 26361415
- Arterial structure and function in inflammatory bowel disease. — World journal of gastroenterology 2015 · PMID 26523102
- Should we expand the concept of coronary heart disease equivalents? — Current opinion in cardiology 2014 · PMID 25029454
- Comparison of inflammation, arterial stiffness and traditional cardiovascular risk factors between rheumatoid arthritis and inflammatory bowel disease — Journal of Inflammation 2014 · PMID 25337037
- Psoriasis. — The journal of the Royal College of Physicians of Edinburgh 2013 · PMID 24350319
- Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice. — Arteriosclerosis, thrombosis, and vascular biology 2011 · PMID 22075248
- Psoriasis comorbidities. — Journal of cutaneous medicine and surgery 2009 · PMID 19799830
- Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls — Nature 2007 · PMID 17554300
Clinical trials (4)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT05986136 | Activation of Autophagy and Suppression of Apoptosis by Dapagliflozin Attenuates Inflammatory Bowel Disease | RECRUITING | INTERVENTIONAL | Mesalamine, Dapagliflozin 10mg Tab |
| NCT01793168 | Coordination of Rare Diseases at Sanford | RECRUITING | OBSERVATIONAL | |
| NCT04924686 | A Bacterial Bi-functional Peptidoglycan Hydrolase Sheds NOD2 Ligands to Regulate Gut Homeostasis | UNKNOWN | OBSERVATIONAL | Observational studies, no intervention |
| NCT03778918 | The Comparison Between That Expression Pattern and Disease Activity of Variable Biomarkers in Inflammatory Bowel Disease Patients and General Control Group. Multicenter, Prospective Study | UNKNOWN | OBSERVATIONAL | inflammatory bowel disease, IBS or Normal Control |
Genetic associations (0)
None linked.