B
Lead exposure
Environmental & OccupationalLab test / biomarkerriskmodifiable
25
evidence score
Also known as: blood lead, lead
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 15.4meta-analyses: 9.1trials: 0genetic: 0MR bonus:
References (34)
2 meta-analyses / systematic reviews- METALead exposure from honey: meta-analysis and risk assessment for the Arab region. — Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 2024 · PMID 38270899
- METALead exposure and cardiovascular disease--a systematic review. — Environmental health perspectives 2006 · PMID 17431501
- Associations Between Lead and Cadmium Exposure and Subclinical Cardiovascular Disease in U.S. Adults. — Cardiovascular toxicology 2025 · PMID 39873882
- Health risks related to environmental and occupational lead exposure. — Kardiologia polska 2025 · PMID 39878639
- Exposure to Lead and Coronary Artery Atherosclerosis: A Swedish Cross-Sectional Population-Based Study. — Journal of the American Heart Association 2025 · PMID 40035389
- Global burden of peripheral arterial disease (1990-2021), global burden trends and the impact of blood lead on peripheral arterial disease: a multidimensional analysis based on NHANES, GBD, and Mendelian randomization. — Journal of translational medicine 2025 · PMID 40269919
- Removing lead from the global economy. — The Lancet. Planetary health 2024 · PMID 39515356
- Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation. — Cells 2023 · PMID 36899953
- Early-life exposure to lead changes cardiac development and compromises long-term cardiac function. — The Science of the total environment 2023 · PMID 37652374
- Global health burden and cost of lead exposure in children and adults: a health impact and economic modelling analysis. — The Lancet. Planetary health 2023 · PMID 37714172
- Blood Lead Levels and Risk of Deaths from Cardiovascular Disease. — The American journal of cardiology 2022 · PMID 35351283
- Burden of Peripheral Artery Disease and Its Attributable Risk Factors in 204 Countries and Territories From 1990 to 2019 — Frontiers in Cardiovascular Medicine 2022 · PMID 35498034
- Burden of cardiovascular disease attributable to dietary lead exposure in adolescents and adults in China. — The Science of the total environment 2022 · PMID 35636555
- Associations of exposure to lead and cadmium with risk of all-cause and cardiovascular disease mortality among patients with type 2 diabetes. — Environmental science and pollution research international 2022 · PMID 35670945
- Occupational risk factors for hypertension. — Journal of hypertension 2022 · PMID 35950984
- Epigenetic Biomarkers of Lead Exposure and Cardiovascular Disease: Prospective Evidence in the Strong Heart Study. — Journal of the American Heart Association 2022 · PMID 36382957
- Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality-A Preliminary Study. — International journal of environmental research and public health 2021 · PMID 34206881
- E-waste lead exposure and children's health in China. — The Science of the total environment 2020 · PMID 32460072
- Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 — The Lancet 2020 · PMID 33069327
- Lead exposure and its association with cardiovascular disease and diabetic kidney disease in middle-aged and elderly diabetic patients. — International journal of hygiene and environmental health 2020 · PMID 33212357
- Low-level lead exposure and mortality in US adults: a population-based cohort study — The Lancet Public Health 2018 · PMID 29544878
- Childhood Lead Exposure and Adult Neurodegenerative Disease. — Journal of Alzheimer's disease : JAD 2018 · PMID 29865081
- The effect of environmental lead exposure on human health and the contribution of inflammatory mechanisms, a review. — Environment international 2018 · PMID 30125858
- Low-level lead exposure and cardiovascular disease: the roles of telomere shortening and lipid disturbance. — The Journal of toxicological sciences 2018 · PMID 30404996
- Association of lead exposure with cardiovascular risk factors and diseases in Chinese adults. — Environmental science and pollution research international 2017 · PMID 28799038
- Lead Exposure in Different Organs of Mammals and Prevention by Curcumin-Nanocurcumin: a Review. — Biological trace element research 2015 · PMID 26005056
- Metal pollutants and cardiovascular disease: mechanisms and consequences of exposure. — American heart journal 2014 · PMID 25458643
- Combined exposure to lead, inorganic mercury and methylmercury shows deviation from additivity for cardiovascular toxicity in rats. — Journal of applied toxicology : JAT 2014 · PMID 25523840
- Cadmium exposure and cardiovascular disease in the 2005 Korea National Health and Nutrition Examination Survey. — Environmental research 2010 · PMID 21055738
- Environmental and occupational exposure to lead as a potential risk factor for cardiovascular disease. — Environmental toxicology and pharmacology 2010 · PMID 21787694
- Mechanisms of lead-induced poisoning. — Georgian medical news 2009 · PMID 19644200
- Mechanisms of lead-induced hypertension and cardiovascular disease. — American journal of physiology. Heart and circulatory physiology 2008 · PMID 18567711
- Cardiovascular effects of lead exposure. — The Indian journal of medical research 2008 · PMID 19106438
- Lead toxicity, a review of the literature. Part 1: Exposure, evaluation, and treatment. — Alternative medicine review : a journal of clinical therapeutic 2006 · PMID 16597190
Clinical trials (0)
None linked.
Genetic associations (0)
None linked.