B
Left ventricular hypertrophy
Imaging & Subclinical DiseaseImaging markerriskpartially modifiable
33
evidence score
Also known as: cardiac hypertrophy, hypertrophy, left ventricle hypertrophy, left ventricular mass, lvh
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 16.3meta-analyses: 9.1trials: 7.8genetic: 0MR bonus:
References (42)
2 meta-analyses / systematic reviews- METAIndependent ischemic stroke risk factors in older Americans: a systematic review — Aging 2019 · PMID 31127075
- METACardiovascular disease risk factors in chronic kidney disease: A systematic review and meta-analysis. — PloS one 2018 · PMID 29561894
- Exploring the impact of metabolic comorbidities on epicardial adipose tissue in heart failure with preserved ejection fraction. — Cardiovascular diabetology 2025 · PMID 40121452
- The role of epicardial adipose tissue remodelling in heart failure with preserved ejection fraction. — Cardiovascular research 2025 · PMID 40238568
- Nonatherosclerotic Cardiovascular Disease in Chronic Kidney Disease. — Cardiology clinics 2025 · PMID 40582730
- Cardiometabolic heart failure with preserved ejection fraction: from molecular signatures to personalized treatment. — Cardiovascular diabetology 2025 · PMID 40611109
- Hidden Cardiovascular Risk: Arterial Stiffness and Left Ventricular Remodeling as Potential Indicators of Masked Hypertension. — Journal of clinical hypertension (Greenwich, Conn.) 2025 · PMID 40685757
- Cathepsin K: a novel association with glucose intolerance, insulin resistance, and subclinical atherosclerosis in T2DM. — Journal of translational medicine 2025 · PMID 41039522
- Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis. — Clinical and experimental nephrology 2024 · PMID 38643287
- Proteomics, Human Environmental Exposure, and Cardiometabolic Risk. — Circulation research 2024 · PMID 38662804
- Diabetic Cardiomyopathy: Role of Cell Death, Exosomes, Fibrosis and Epicardial Adipose Tissue. — International journal of molecular sciences 2024 · PMID 39273428
- Fibroblast Growth Factor-23 and Risk of Cardiovascular Diseases: A Mendelian Randomization Study. — Clinical journal of the American Society of Nephrology : CJASN 2023 · PMID 36719157
- Contaminant Metals as Cardiovascular Risk Factors: A Scientific Statement From the American Heart Association. — Journal of the American Heart Association 2023 · PMID 37306302
- FGF23 and klotho at the intersection of kidney and cardiovascular disease. — Nature reviews. Cardiology 2023 · PMID 37443358
- Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study. — Circulation 2023 · PMID 38031887
- Central and brachial pulse pressure predicts cardiovascular and renal events in treated hypertensive patients. — Blood pressure 2022 · PMID 35438015
- Atherosclerotic renovascular disease and cardiovascular risk: new concepts. — Polish archives of internal medicine 2022 · PMID 36533812
- Prevalence and determinants of elevated D-dimer in patients with hypertrophic cardiomyopathy. — Biomarkers in medicine 2020 · PMID 32057272
- NAFLD, and cardiovascular and cardiac diseases: Factors influencing risk, prediction and treatment. — Diabetes & metabolism 2020 · PMID 33296704
- Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective — Frontiers in Pharmacology 2020 · PMID 33304270
- The Impact of hs-CRP on Cardiovascular Risk Stratification in Pilots and Air Traffic Controllers. — Aerospace medicine and human performance 2020 · PMID 33334409
- Anemia and coronary artery disease: pathophysiology, prognosis, and treatment. — Coronary artery disease 2018 · PMID 29280914
- Education and hypertension: impact on global cardiovascular risk. — Acta cardiologica 2017 · PMID 28657499
- Association between low education and higher global cardiovascular risk. — Journal of clinical hypertension (Greenwich, Conn.) 2015 · PMID 25703272
- MicroRNAs in cardiovascular disease: an introduction for clinicians — Heart 2015 · PMID 25814653
- High-Sensitivity Cardiac Troponin T and Risk of Hypertension. — Circulation 2015 · PMID 26152706
- GDF-15 as a Target and Biomarker for Diabetes and Cardiovascular Diseases: A Translational Prospective. — Journal of diabetes research 2015 · PMID 26273671
- Lifelong Cyclic Mechanical Strain Promotes Large Elastic Artery Stiffening: Increased Pulse Pressure and Old Age-Related Organ Failure. — The Canadian journal of cardiology 2015 · PMID 26961664
- Ankle-brachial index and ventricular hypertrophy in arterial hypertension. — Arquivos brasileiros de cardiologia 2012 · PMID 22323323
- Mitochondria and cardiovascular aging. — Circulation research 2012 · PMID 22499901
- Obstructive sleep apnea and hypertrophic cardiomyopathy: a common and potential harmful combination. — Sleep medicine reviews 2012 · PMID 23046848
- Metabolic Abnormalities, Cardiovascular Disease Risk Factors, and GFR Decline in Children with Chronic Kidney Disease — Clinical Journal of the American Society of Nephrology 2011 · PMID 21841064
- Cardiovascular responses to cold exposure. — Frontiers in bioscience (Elite edition) 2010 · PMID 20036896
- Brachial arterial pressure to assess cardiovascular structural damage: an overview and lessons from clinical trials. — Journal of nephrology 2008 · PMID 18264933
- Uric Acid and Incident Kidney Disease in the Community — Journal of the American Society of Nephrology 2008 · PMID 18337481
- Hypertension in older people: part 1. — Journal of clinical hypertension (Greenwich, Conn.) 2006 · PMID 16760685
- Risk Factors for Ischemic Stroke Subtypes — Stroke 2006 · PMID 16931783
- Normalization of Hemoglobin Level in Patients with Chronic Kidney Disease and Anemia — New England Journal of Medicine 2006 · PMID 17108342
- Cardiovascular Mortality Risk in Chronic Kidney Disease — JAMA 2005 · PMID 15827312
- Uric Acid, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension — Hypertension 2005 · PMID 16380520
- Uric acid: role in cardiovascular disease and effects of losartan. — Current medical research and opinion 2004 · PMID 15025846
- Arterial Stiffening as a Possible Risk Factor for Both Atherosclerosis and Diastolic Heart Failure — Hypertension Research 2004 · PMID 15750255
Clinical trials (5)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT03089333 | Effects of Dapagliflozin, an SGLT2 Inhibitor, on Hemodynamic Parameters, Target Organ Damage and Obesity Profile in Resistant Hypertensive Subjects | COMPLETED | INTERVENTIONAL | Dapagliflozin 10mg, Glibenclamide 5Mg Tablet |
| NCT00738972 | Left Ventricular Hypertrophy Reduction With Statins in Hypertensives Patients. | TERMINATED | INTERVENTIONAL | valsartan, pravastatin, simvastatin |
| NCT05373732 | Stress Reduction in the Prevention of Left Ventricular Hypertrophy: A Randomized Controlled Trial of Transcendental Meditation and Health Education in Hypertensive African Americans | COMPLETED | INTERVENTIONAL | meditation, Health education control |
| NCT05942729 | Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data. | RECRUITING | OBSERVATIONAL | Determine the etiology of hypokinetic and hypertrophic heart disease on transthoracic echocardiography data alone |
| NCT01305304 | Magnetic Resonance Technique in the Assessment of Exercise-induced Long- and Short-Term Changes in Cardiac Function and Morphology | COMPLETED | OBSERVATIONAL | repeated long term endurance exercise, Other |
Genetic associations (0)
None linked.