C
Low HDL cholesterol
Lipids & LipoproteinsLab test / biomarkerriskmodifiable
13
evidence score
Also known as: HDL cholesterol, low, hypo-HDL, low and/or dysfunctional high-density lipoproteins (HDL), low high-density lipoprotein cholesterol (HDL-C), low high-density lipoprotein cholesterol (HDL-C) levels, low-plasma HDL cholesterol
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 7.8meta-analyses: 0trials: 4.8genetic: 0MR bonus:
References (5)
0 meta-analyses / systematic reviews- Socioeconomic status and cardiovascular risk in urban South Asia: The CARRS Study. — European journal of preventive cardiology 2015 · PMID 25917221
- High-density lipoproteins and cerebrovascular integrity in Alzheimer's disease. — Cell metabolism 2014 · PMID 24508505
- Update on pediatric hyperlipidemia. — Current opinion in pediatrics 2014 · PMID 24553633
- Non-HDL cholesterol as a measure of atherosclerotic risk. — Journal of atherosclerosis and thrombosis 2004 · PMID 15067193
- Pathophysiology of dyslipidemia and increased cardiovascular risk in HIV lipodystrophy: a model of 'systemic steatosis'. — Current opinion in lipidology 2004 · PMID 15166810
Clinical trials (2)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT00986986 | Prospective Randomized Pilot Study of the Effect of Niaspan on Endothelial Function in HIV-infected Subjects With Low HDL Cholesterol Levels | COMPLETED | INTERVENTIONAL | extended release niacin |
| NCT00261352 | A 24-Week Randomised, Double-Blind, Parallel-Group, Multi-Centre, Active-Controlled (Metformin or Metformin Combined With Fenofibrate) Study to Evaluate the Lipid Metabolic Effects, Safety and Tolerability of Tesaglitazar Therapy in Patients With Type 2 Diabetes and Low HDL-Cholesterol on a Fixed Background Therapy With a Statin | TERMINATED | INTERVENTIONAL | Tesaglitazar, Metformin, Fenofibrate |
Genetic associations (0)
None linked.