B
Migraine
Comorbid ConditionsDisease / conditionriskpartially modifiable
27
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 12.8meta-analyses: 6trials: 8.4genetic: 0MR bonus:
References (18)
1 meta-analyses / systematic reviews- METAMigraine and pregnancy-related headaches as a risk factor for cardiovascular and cerebrovascular events in pregnancy: a systematic review and meta-analysis of over 94 million pregnancies. — The journal of headache and pain 2025 · PMID 41233752
- Gestational Hypertension, Preeclampsia, and Eclampsia and Future Neurological Disorders. — JAMA neurology 2025 · PMID 39714850
- Causality between migraine and cardiovascular disease: a bidirectional Mendelian randomization study. — The journal of headache and pain 2024 · PMID 39135164
- The association between health anxiety, physical disease and cardiovascular risk factors in the general population - a cross-sectional analysis from the Tromsø study: Tromsø 7. — BMC primary care 2022 · PMID 35655153
- Migraine and Ischemic Stroke: A Mendelian Randomization Study. — Neurology and therapy 2021 · PMID 34904213
- The progress of gut microbiome research related to brain disorders — Journal of Neuroinflammation 2020 · PMID 31952509
- Clinico-radiological profile of CVT patients and its correlation with D-dimer. — Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2020 · PMID 32336633
- Headache: Headache Emergencies. — FP essentials 2018 · PMID 30346681
- Development and validation of QRISK3 risk prediction algorithms to estimate future risk of cardiovascular disease: prospective cohort study — BMJ 2017 · PMID 28536104
- Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016 — The Lancet 2017 · PMID 28919117
- Migraine and stroke. — Stroke and vascular neurology 2017 · PMID 28989805
- microRNA profiling in atherosclerosis, diabetes, and migraine. — Annals of medicine 2016 · PMID 27560467
- Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015 — The Lancet 2016 · PMID 27733282
- Lifestyle Risk Factors for Ischemic Stroke and Transient Ischemic Attack in Young Adults in the Stroke in Young Fabry Patients Study — Stroke 2012 · PMID 23150649
- Migraine and cerebrovascular risk. — Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2010 · PMID 20464602
- Migraine and cerebrovascular disease. — Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 2007 · PMID 17508164
- Migraine comorbidity constellations. — Headache 2007 · PMID 17578536
- Primary Prevention of Ischemic Stroke — Stroke 2006 · PMID 16675728
Clinical trials (6)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT01225263 | Combined Statin and Vitamin D Therapy for Prophylactic Treatment of Episodic Migraine | COMPLETED | INTERVENTIONAL | Simvastatin, Vitamin D, Placebo |
| NCT00662818 | A Multicenter, Randomized, Double-Blind, Placebo- and Active Controlled, Crossover Study to Evaluate the Safety and Efficacy of MK-0974 in the Treatment of Acute Migraine in Patients With Stable Vascular Disease | COMPLETED | INTERVENTIONAL | Telcagepant, Acetaminophen/Paracetamol, Placebo to Telcagepant |
| NCT00529945 | The Paradigm IV Trial - PFx Closure System in Subjects With Cryptogenic Stroke, Transient Ischemic Attack, Migraine or Decompression Illness | SUSPENDED | INTERVENTIONAL | PFx Closure System |
| NCT00196040 | Feasibility Study of the PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemic Attack, Migraine or Decompression Illness | COMPLETED | INTERVENTIONAL | PFX Closure System |
| NCT04686253 | Internal Microstructure of Patent Foramen Ovale Related to Cryptogenic Stroke, Transient Ischemic Attack or Migraine | RECRUITING | OBSERVATIONAL | not appliable |
| NCT01114815 | Natural History of CADASIL: Migraine, Diagnosis and Misdiagnosis | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.