D
MTHFR gene mutation
Genetic & Family HistoryGenetic / heritablerisknon modifiable
6
evidence score
Also known as: MTHFR mutations, mutations of the enzymes MTHFR and CBS
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 3meta-analyses: 0trials: 3genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Metabolism of homocysteine and its relationship with cardiovascular disease. — Journal of thrombosis and thrombolysis 2004 · PMID 15789174
Clinical trials (1)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT04952324 | MTHFR Gene Mutation C6777T and Concentration of Vitamin B12, Folic Acid, Homocysteine and High Sensitive CRP in the Blood of Pregnant Women With Gestational Diabetes Mellitus. | COMPLETED | OBSERVATIONAL | Blood sampling and determination of MTHFR mutation,vitamin B12, folic acid, homocystein and HS CRP |
Genetic associations (0)
None linked.