C
Nephropathy
Renal & ElectrolyteDisease / conditionriskpartially modifiable
17
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 14.4genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Oxidative Stress and Cardiovascular Dysfunction Associated with Cadmium Exposure: Beneficial Effects of Curcumin and Tetrahydrocurcumin. — The Tohoku journal of experimental medicine 2016 · PMID 27151191
Clinical trials (27)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT04662723 | Multicentre Prospective Open Label Clinical Study to Evaluate the Effect of Personalized Therapy on Patients With Immunoglobulin A Nephropathy. | RECRUITING | INTERVENTIONAL | Corticosteroid, Renin-angiotensin sytem blockers, Sodium-glucose cotransporter 2 inhibitor |
| NCT06501651 | A Prospective, Randomized, Controlled, Multicenter Study of Sacubitril/Valsartan in the Treatment of Patients With Mild to Moderate Essential Hypertension and Type 2 Diabetic Nephropathy: The Hyper-Save Study | NOT YET RECRUITING | INTERVENTIONAL | Sacubitril/Valsartan, Valsartan |
| NCT04027530 | Phase 4, Randomized, Placebo-controlled, Cross-over Trial to Assess the Effect of 4-week Ertugliflozin (SGLT-2 Inhibitor) Therapy on Renal Oxygenation by BOLD-MRI and Renal Oxygen Consumption by PET Using ¹¹C-acetate in T2DM Without Kidney Disease and Healthy Controls. | COMPLETED | INTERVENTIONAL | Ertugliflozin 15 mg |
| NCT04127084 | Effects of SGLT2 Inhibition Treatment on Different Levels of Albuminuria in Patients With Type 2 Diabetes: a Prospective Interventional Study | UNKNOWN | INTERVENTIONAL | SGLT2 Inhibition |
| NCT03755700 | Antioxidants for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization | UNKNOWN | INTERVENTIONAL | Vitamin E, N-acetyl cysteine, Placebo oral capsule |
| NCT03391830 | Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy. Randomised Controlled Study | COMPLETED | INTERVENTIONAL | Atorvastatin-Ascorbic acid, Placebo |
| NCT04705506 | Effect of Gemigliptin on Biomarkers of Kidney Injury and Vascular Calcification in Diabetic Nephropathy: A Randomized Controlled Trial | COMPLETED | INTERVENTIONAL | Gemigliptin |
| NCT02442921 | The Effect of Colchicine Treatment on the Progression of Proteinuria in Patients With Diabetic Nephropathy. | UNKNOWN | INTERVENTIONAL | Colchicine, Placebo |
| NCT02575092 | Department of Geriatrics | COMPLETED | INTERVENTIONAL | Enalapril Maleate Tablets(as the program-based antihypertension), Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension), Placebo |
| NCT02065791 | A Randomized, Double-blind, Event-driven, Placebo-controlled, Multicenter Study of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Subjects With Type 2 Diabetes Mellitus and Diabetic Nephropathy | COMPLETED | INTERVENTIONAL | Canagliflozin, Placebo |
| NCT02035891 | Low-dose Colchicine Intervention in Patients With Type 2 Diabetes Mellitus and Microalbuminuria: Chongqing Study | UNKNOWN | INTERVENTIONAL | colchicine 0.5mg/d, placebo 0.5mg/d |
| NCT01588795 | Renal Denervation in Patients With Diabetic Nephropathy and Persistent Proteinuria | COMPLETED | INTERVENTIONAL | Percutaneous renal denervation and TMNS, Standardized antiproteinuric medication regimen includes an angiotensin receptor blocker , a diuretic , 25OH vitamin D3 and a statin |
| NCT02113540 | Atorvastatin and Prevention of Contrast Induced Nephropathy Following Coronary Angiography | UNKNOWN | INTERVENTIONAL | Atorvastatin |
| NCT02471599 | Effect of Tonsillectomy on Longterm Renal Outcome of IgA Nephropathy :a Prospective,Randomized,Controlled Study. | SUSPENDED | INTERVENTIONAL | tonsillectomy, non-tonsillectomy |
| NCT01093157 | A Dose-finding Pilot Study of ACTH (Adrenocorticotropic Hormone) on the Proteinuria and Serum Lipoprotein Profile in Patients With Idiopathic Membranous Nephropathy (MN) | COMPLETED | INTERVENTIONAL | Adrenocorticotrophic hormone ACTH |
| NCT00805753 | A Dose-Finding Pilot Study of ACTH on the Serum Lipoprotein Profile and Proteinuria in Patients With Idiopathic Membranous Nephropathy (MN) | COMPLETED | INTERVENTIONAL | ACTH |
| NCT00554502 | Supportive Versus Immunosuppressive Therapy for the Treatment Of Progressive IgA Nephropathy | COMPLETED | INTERVENTIONAL | supportive therapy with: ACE-inhibitor / ARB / Statin, supportive and immunosuppressive therapy |
| NCT00461136 | An Open-label, One-period, One-treatment Study to Evaluate the Time Course of the Antiproteinuric and Blood Pressure Lowering Effects After Initiation of Renin Inhibition With Aliskiren in Type 2 Diabetes Suffering From Incipient and/or Established Nephropathy | COMPLETED | INTERVENTIONAL | Aliskiren |
| NCT00199927 | A Prospective, Randomized, Multicenter Trial Testing the Antiproteinuric Effect of Statins Added to Combined ACE-inhibitor and Angiotensin Receptor Antagonist Therapy in Proteinuric, Chronic Nephropathies | COMPLETED | INTERVENTIONAL | Fluvastatin, standard therapy |
| NCT07444203 | Transformative Research in Diabetic Nephropathy 2.0: A Proof of Principle Study of SGLT2 Inhibitors (TRIDENT 2.0) | RECRUITING | OBSERVATIONAL | Sodium-glucose cotransporter 2 inhibitors (SGLT2i), Renin-angiotensin-aldosterone system blockade, Glucagon-like peptide-1 receptor agonists (GLP 1 RA) |
| NCT06065852 | National Registry of Rare Kidney Diseases (RaDaR) | RECRUITING | OBSERVATIONAL | |
| NCT07476248 | The Non-high-density Lipoprotein Cholesterol (Non-HDL-C) to High-density Lipoprotein Cholesterol (HDL-C) Ratio (NHHR) and Its Association With Occurrence of Diabetic Nephropathy in Patients With Diabetes Mellitus | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT05047471 | Healthy China - The Improvement Projects for the Screening Ability of Diabetes and Its Complications And for the Standardized Ability of Diagnosis and Treatment for Patients With Early Diabetic Nephropathy | UNKNOWN | OBSERVATIONAL | |
| NCT04163484 | Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease | COMPLETED | OBSERVATIONAL | Iodinated contrast |
| NCT02192372 | Impact of Metabolic Syndrome on Development of Contrast Induced Nephropathy After Elective Percutaneous Coronary Intervention | COMPLETED | OBSERVATIONAL | |
| NCT00842868 | The CASABLANCA Study: Catheter Sampled Blood Archive in Cardiovascular Diseases. An Observational Biomarker Study | COMPLETED | OBSERVATIONAL | |
| NCT00498147 | Does Managed Diabetes Care Decrease Cardiovascular Complications of Diabetes? | UNKNOWN | OBSERVATIONAL | ADEC Program |
Genetic associations (0)
None linked.