C
Neutrophil-to-lymphocyte ratio
Inflammatory & ImmuneLab test / biomarkerriskpartially modifiable
26
evidence score
Also known as: Neutrophil-lymphocyte ratio, neutrophil-lymphocyte ratio, nlr
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 10meta-analyses: 9.1trials: 7genetic: 0MR bonus:
References (9)
2 meta-analyses / systematic reviews- METANeutrophil-to-lymphocyte ratio as a prognostic biomarker in patients with peripheral artery disease: A systematic review and meta-analysis. — Vascular medicine (London, England) 2024 · PMID 39415502
- METANeutrophil Lymphocyte Ratio and Cardiovascular Disease Risk: A Systematic Review and Meta-Analysis. — BioMed research international 2018 · PMID 30534554
- Oxidative stress and inflammation mediate the adverse effects of cadmium exposure on all-cause and cause-specific mortality in patients with diabetes and prediabetes. — Cardiovascular diabetology 2025 · PMID 40158078
- Treatment burden and its impact on residual cardiovascular risk in community-dwelling older adults with cardiometabolic multimorbidity: an exploratory cross-sectional study. — Postgraduate medicine 2025 · PMID 40404562
- Lung function as a modifiable risk factor for Ischemic Stroke: Evidence from the UK biobank. — Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2025 · PMID 41015216
- BRCC3-Mediated NLRP3 Deubiquitylation Promotes Inflammasome Activation and Atherosclerosis inClonal Hematopoiesis. — Circulation 2023 · PMID 37781816
- Galectin-3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling. — Acta physiologica (Oxford, England) 2022 · PMID 34995420
- Ceramides and Cardiovascular Risk Factors, Inflammatory Parameters and Left Ventricular Function in AMI Patients. — Biomedicines 2022 · PMID 35203637
- Neutrophil to lymphocyte ratio and cardiovascular diseases: a review — Expert Review of Cardiovascular Therapy 2012 · PMID 23259445
Clinical trials (4)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT03097692 | Variable Types of Preconditioning,is There a Different Impact Upon Multiorgan Function After Open Heart Surgery ? | COMPLETED | INTERVENTIONAL | ischemic preconditioning, Pharmacologic preconditionig |
| NCT07089524 | A Comparative Study Between Neutrophil/Lymphocyte Ratio and Lactate/Albumin Ratio as Predictive Inflammatory Markers for Sepsis in Patients With Lower Respiratory Tract Infection in ICU | RECRUITING | OBSERVATIONAL | |
| NCT07551102 | Relationship Between Inflammatory (Hs-CRP, Neutrophil-to-Lymphocyte Ratio) and Cardiac (Troponin) Biomarkers, and Cardiac Dysfunction in Acute Coronary Syndrome. | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT05031195 | Preoperative Neutrophil to Lymphocyte Ratio, Platelet to Lymphocyte Ratio, and Mean Platelet Volume as Predictors of 1 Year Mortality in Patients Undergoing an Open Repair of Abdominal Aortic Aneurysms: a Retrospective Study | COMPLETED | OBSERVATIONAL | 1st tertile, 2nd tertile, 3rd tertile |
Genetic associations (0)
None linked.