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Obstructive sleep apnea

Comorbid ConditionsDisease / conditionriskpartially modifiable
52
evidence score

Also known as: Obstructive sleep apnea (OSA), obstructive sleep apnea (OSA), obstructive sleep apnoea, obstructive sleep apnoea syndrome, sleep apnea

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 21.4meta-analyses: 15.8trials: 15genetic: 0MR bonus:

References (137)

5 meta-analyses / systematic reviews

Clinical trials (33)

NCTTitleStatusTypeInterventions
NCT05846490Impact of Obstructive Sleep Apnea Treatment on Blood Pressure Control in Chronic Kidney Disease: A Randomized TrialUNKNOWNINTERVENTIONALCPAP, Usual care
NCT06690723Exploring the Synergistic Effect of Vitamin D and SGLT-2 Inhibitor on Cardio-metabolic Markers and the Renin Angiotensin Aldosterone System in CPAP-naive Obstructive Sleep Apnea PopulationCOMPLETEDINTERVENTIONALDapagliflozin (Forxiga), Vitamin D3 ( Colecalciferol), Vitamin D3 plus Dapagliflozin
NCT03930563Acute Beetroot Juice Supplementation and Peripheral Chemoreflex Sensitivity in Patients With Obstructive Sleep ApneaCOMPLETEDINTERVENTIONALPre-beetroot juice supplementation, Post-beetroot juice supplementation
NCT03936751Impact of Obstructive Sleep Apnea Treatment on Cardiovascular Events in Patients With Acute Cardiogenic Pulmonary Edema: a Multicenter Randomized Controlled Study (CPAP-CARE STUDY).TERMINATEDINTERVENTIONALCPAP, Nasal Strips
NCT04212260Strengthening Oropharyngeal Muscles as a Novel Approach to Treat Obstructive Sleep Apnea After Stroke: A Randomized Feasibility StudyCOMPLETEDINTERVENTIONALOropharyngeal exercises, Sham control
NCT03227939Effect of Laparoscopic Sleeve Gastrectomy (LSG) Plus Uvulopalatopharyngoplasty and Adenoidectomy/Tonsillectomy on Severe Obstructive Sleep Apnea & Hyponea Syndromes in Moderate-to-severe Obese Patients: an Open-label Randomized Controlled Clinical TrialUNKNOWNINTERVENTIONALLaparoscopic sleeve gastrectomy（LSG）, Uvulopalatopharyngoplasty(UPPP) and Adenoidectomy/Tonsillectomy
NCT04179942Fractional Exhaled Nitric Oxide and CRP Levels in Egyptian Patients With Obstructive Sleep Apnea SyndromeCOMPLETEDINTERVENTIONALFractional exhaled nitric oxide and CRP levels
NCT03049306Propranolol for Sleep Apnea TherapyCOMPLETEDINTERVENTIONALPropranolol Oral Tablet, Placebo Oral Tablet
NCT03665818The Influence of Mandibular Advancement Device Treating OSAHS on Primary Prevention of Ischemic StrokeCOMPLETEDINTERVENTIONALoral appliance treatment
NCT02796638Adaptive Servo-Ventilation In Acute Heart Failure Patients Protecting the HeartUNKNOWNINTERVENTIONALAdaptive Servo-Ventilation
NCT02454023SLEep APnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke (SLEAP SMART): A Randomized Controlled TrialCOMPLETEDINTERVENTIONALPortable sleep monitor (ApneaLink Air), In-laboratory polysomnography
NCT01896661The Effect of Antihypertensive Agents Over Sleep Apnea: a Randomized Controlled TrialCOMPLETEDINTERVENTIONALDiuretics, Calcium Channel Blockers
NCT01935765Sleep Apnea in Type 1 Diabetes : Prevalence, Role of Glycemic Control and Autonomic NeuropathyCOMPLETEDINTERVENTIONALPolysomnography, Evaluation of the autonomous nervous system, Clinical examination of the sleep
NCT01812993Reversal of the Neurological Deficit in Acute Stroke With the Signal of Efficacy Trial of Auto BPAP to Limit Damage From Suspected Sleep Apnea (Reverse-STEAL): A Multicenter Randomized StudyUNKNOWNINTERVENTIONALNon-invasive ventilatory treatment with auto-BPAP
NCT01508754Efficacy of Continuous Positive Airway Pressure (CPAP) on Blood Pressure Control of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome (OSAS).COMPLETEDINTERVENTIONALContinuous positive airway pressure treatment
NCT01366625Effects of Renal Denervation on Blood Pressure and Clinical Course of Obstructive Sleep Apnea in Patients With Resistant HypertensionCOMPLETEDINTERVENTIONALRenal denervation with a catheter-based procedure (Symplicity® Catheter System)
NCT01446913Sleep Apnea in TIA/Stroke: Reducing Cardiovascular Risk With Positive Airway PressureCOMPLETEDINTERVENTIONALStandard CPAP Intervention, Enhanced CPAP Intervention
NCT02127177Long-term Effects of Continuous Positive Airway Pressure on Lipidemia and High-sensitivity C-reactive Protein Levels in Nonobese Patients With Coronary Heart Disease and Obstructive Sleep ApneaCOMPLETEDINTERVENTIONALContinuous Positive Airway Pressure Ventilator
NCT00984308Diagnosis and Treatment of Sleep Apnea in Cerebrovascular DiseaseCOMPLETEDINTERVENTIONALCPAP Therapy for Newly Diagnosed Obstructive Sleep Apnea (OSA)
NCT00746902Study of the Relationships Between Refractory Hypertension, Overweight/Obesity and Sleep Apnea SyndromeCOMPLETEDINTERVENTIONALnCPAP
NCT00518128Measuring Effectiveness in Sleep Apnea SurgeryCOMPLETEDINTERVENTIONALSurgical OSA treatment, Positive Airway Pressure Therapy
NCT00507078Biomarkers in Obstructive Sleep Apnea SurgeryCOMPLETEDINTERVENTIONALSurgical treatment for OSA
NCT00251290Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic AttackCOMPLETEDINTERVENTIONALauto-titrating continuous positive airway pressure
NCT07427589Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep ApneaRECRUITINGOBSERVATIONALContinuous positive airway pressure, Mandibular advancement device, Hypoglossal nerve stimulation
NCT04326244The Relationship Between Obesity-related Molecular Typing and Traditional Chinese Medicine ConstitutionUNKNOWNOBSERVATIONALblood test, genetic test, Constitution in Chinese Medicine Questionnaire
NCT04903639Obstructive Sleep Apnea Prevalence in Patients With Chronic Obstructive Pulmonary DiseasesCOMPLETEDOBSERVATIONALsleep study
NCT02559739Sleep Deficiency and Sleep Fragmentation and Their Impact on the Short- and Long-term Outcome of Ischemic Stroke and Transient Ischemic Attacks - a Two-center Prospective Observational Cohort StudyCOMPLETEDOBSERVATIONAL
NCT03362385Impact of Obstructive Sleep Apnea and Continuous Positive Airway Pressure Therapy on Outcomes in Patients With Acute Coronary Syndrome: The OSA-ACS ProjectCOMPLETEDOBSERVATIONALPatients with OSA based on sleep study, Patients without OSA based on sleep study
NCT02363114DOC Utility: Simple Screening of Depression, Obstructive Sleep Apnea and Cognitive Impairment to Identify Stroke Clinic Patients at Risk of Adverse OutcomesUNKNOWNOBSERVATIONAL
NCT02131610Epigenetics Modifications and Subclinical Atherosclerosis in Obstructive Sleep Apnea: The EPIOSA StudyUNKNOWNOBSERVATIONAL
NCT03070769Evaluation of Inflammatory Markers in a Large Sample of Obstructive Sleep Apnea PatientsCOMPLETEDOBSERVATIONALVenous blood collection for biomarkers measurements
NCT01528462Does Acute Management of Sleep Disorders Improve Outcomes After Non-disabling Cerebrovascular Events?COMPLETEDOBSERVATIONALExpedited Treatment of Sleep Disorders
NCT00926874A Comparative Study of Structural and Functional Arterial Properties After an Ischaemic Stroke or an Acute Coronary SyndromeUNKNOWNOBSERVATIONAL

Genetic associations (0)

None linked.