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Periodontitis

Inflammatory & ImmuneDisease / conditionriskpartially modifiable
54
evidence score

Also known as: Periodontal disease, periodontal disease

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 21.6meta-analyses: 20trials: 12.3genetic: 0MR bonus:

References (142)

14 meta-analyses / systematic reviews

Clinical trials (16)

NCTTitleStatusTypeInterventions
NCT07343804THE EFFECT OF ENDODONTIC TREATMENT ON CARDIOVASCULAR RISK BIOMARKERS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE : A RANDOMIZED CONTROLLED TRIALRECRUITINGINTERVENTIONALroot canal treatment and intracanal medicament
NCT04980768Association of Apical Periodontitis With Systemic Levels of Hs-CRP and Hemogram Indices: A Clinical Study.UNKNOWNINTERVENTIONALRoot canal treatment
NCT03755362Treatment of Periodontitis to Prevent Dementia in Older Adults With Asymptomatic Carotid Artery Stenosis and Mild Cognitive ImpairmentTERMINATEDINTERVENTIONALStandard Treatment, Intensive Treatment
NCT03908606Prognostic Value of Serum Hs-CRP in Periodontitis Patients With or Without Type 2 Diabetes Following Non-surgical Periodontal TherapyCOMPLETEDINTERVENTIONALScaling and root planing
NCT04540328Effect of Non-surgical Peridontal Treatment on Cardiovascular Risk Markers in Patients With Severe Chronic PeriodontitisCOMPLETEDINTERVENTIONALNon-surgical periodontal treatment
NCT02417376Effect of Nonsurgical Periodontal Treatment on Systemic Risk Markers of Cardiovascular Disease Clinically and Biochemically: A Randomized TrialCOMPLETEDINTERVENTIONALpiezoelectric ultrasonic scaler (frequency of 28-36 KHz), Gracey curettes
NCT01951547The Effect of Non-surgical Periodontal Therapy on Host Response and Microbiological Profile of Type 2 Diabetics With Periodontal Disease.COMPLETEDINTERVENTIONALNonsurgical periodontal therapy, Oral hygiene instructions
NCT07296965The Role of the Oral Microbiome in Carotid Atherosclerosis: Investigating in a Cross-sectional Study the Microbial Influence on Plaque Development and Vulnerability Based on Biobank DataRECRUITINGOBSERVATIONALSample Collection
NCT07504744Evaluation of the Expression of Klotho Gene and Its Protein Level, Determination of Red Complex Bacteria, and the Estimation of Periodontal Viruses in Patients With and Without Periodontitis and Acute Coronary SyndromeNOT YET RECRUITINGOBSERVATIONAL
NCT06933797Evaluation of the Changes in LRP5 and TPH1 Levels Due to Periodontal InflammationCOMPLETEDOBSERVATIONAL
NCT05818657Prevalence of of Apical Periodontal in Patients Chronic Kidney Disease & Its Association With Markers of Kidney Disease.COMPLETEDOBSERVATIONALlevels of CKD markers, Oral health status, apical periodontitis, systemic inflammatory marker, Oral health status, apical periodontitis
NCT04303351The Relationship Between Periodontitis and Atherosclerotic-related Arterial Stenosis in the Chinese PopulationUNKNOWNOBSERVATIONAL
NCT04305171Effect of Non-surgical Periodontal Treatment on Plasma Fibrinogen, Plasminogen Activator Inhibitor 1 and C-reactive Protein Levels in Cardiovascular Disease Patients With PeriodontitisCOMPLETEDOBSERVATIONALnon-surgical periodontal treatment
NCT03345745The Short-Term Effects of Non-Surgical Periodontal Therapy on The Saliva Levels of S100A12, High-Sensitivity C-Reactive Protein and Fetuin-A in Patients With Gingivitis and Chronic PeriodontitisCOMPLETEDOBSERVATIONALsalivary samples
NCT03041480The Association Between Periodontal Status, Serum Lipid Levels and Lipoprotein Associated Lipophosphase A2(Lp-PLA2) in Chronic Periodontitis Subjects and Healthy Controls: A Case Control StudyCOMPLETEDOBSERVATIONALserum lipid levels and Lp-PLA2
NCT02826720Is There a Relationship Between Hyperlipidemia and Periodontitis?COMPLETEDOBSERVATIONALNo intervention was applied

Genetic associations (0)

None linked.