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Physical inactivity

Lifestyle & BehavioralBehavior / exposureriskmodifiable
62
evidence score

Also known as: exercise, inactivity, lack of exercise, physical activity, physically inactive, sedentary, sedentary lifestyle

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 26.8meta-analyses: 20trials: 15genetic: 0MR bonus:

References (483)

33 meta-analyses / systematic reviews

Clinical trials (271)

showing top 60
NCTTitleStatusTypeInterventions
NCT07221266Changes in Motor Function, Quality of Life, Cardiorespiratory Fitness, and Physiological Markers in People With Parkinson's Disease Following Different Exercise Interventions.RECRUITINGINTERVENTIONALGuided Cycling, Non-Contact Boxing, Traditional Physical Therapy Program (Standard of Care)
NCT07027995Food and Fitness With MedicineRECRUITINGINTERVENTIONALExercise is Medicine (EIM), Culinary Education, Food is Medicine
NCT07402642Effect of Early Educational Intervention on Cardiovascular Risk Factors After Acute Coronary SyndromeRECRUITINGINTERVENTIONALMotivational and Individualized Interviewing, Heart-Healthy Dietary Education, Tobacco Cessation Approach
NCT06745544Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes: Protocol for a Randomized Control Trial: DIACTIVERECRUITINGINTERVENTIONALRhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
NCT07091500Effect of GLP-1 Receptor Agonist Therapy With and Without Exercise Training on Muscle Mass and Physical Function in People With ObesityRECRUITINGINTERVENTIONALExercise training, Semaglutide, Therapy Cessation
NCT06686121IMProving Mobility After revasCularizaTion in Peripheral Artery Disease: The IMPACT PAD TrialRECRUITINGINTERVENTIONALHome Based Exercise, Nitrate Rich Beetroot Juice, Attention Control
NCT06410521Personalisation of Non-surgical Treatment in Peripheral Arterial Disease Using a Multicomponent Exercise ApproachRECRUITINGINTERVENTIONALExercise, Usual care
NCT07130318Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Elliptical Aerobic ExerciseRECRUITINGINTERVENTIONALexercise plus diet restriction, diet restriction
NCT06525987Telecoached Exercise Intervention for Connectivity Enhancement in Small Vessel Disease (TELECONNECT-SVD): a Randomized Clinical TrialRECRUITINGINTERVENTIONALPhysical activity
NCT06657976Response to Exercise and Nitric Oxide in Peripheral Artery Disease: The RESIST PAD TrialRECRUITINGINTERVENTIONALSupervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy
NCT06681896Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility StudyRECRUITINGINTERVENTIONALMICROFIT - personalised high intensity interval training exercise rehabilitation and dietary advice
NCT03845036The Effects of Diet and Exercise Interventions in Peripheral Artery DiseaseRECRUITINGINTERVENTIONALDASH Diet plus Home-Based Exercise, Home-Based Exercise
NCT05712395The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery DiseaseRECRUITINGINTERVENTIONALExercise
NCT06130059Pilot Study to Evaluate the Efficacy of Low Dose Colchicine (LoDoCo ®) to Improve Exercise Capacity Among Patients With Chronic Stable HFpEF and Systemic InflammationRECRUITINGINTERVENTIONALLow Dose Colchicine, Placebo
NCT06566976Prehabilitation and Rehabilitation in PAD: A Randomized Exercise Intervention Trial (PREPARE-IT)RECRUITINGINTERVENTIONALExercise Intervention, VAPAHCS Rehabilitation Core Components
NCT06114732Motivating Physical Activity With Behavioural interVention and Electrical Stimulation Remotely in People With Intermittent Claudication (MAvERIC): a Feasibility Randomised Controlled TrialRECRUITINGINTERVENTIONALWalking exercise behaviour change intervention + TENS
NCT06003855Oxygen-guided Supervised Exercise Therapy in Peripheral Artery DiseaseRECRUITINGINTERVENTIONALSupervised exercise therapy
NCT06299956Supervised Exercise-based Rehabilitation for People With Intermittent Claudication - Study Protocol for a Danish Implementation Process (StRiDE).RECRUITINGINTERVENTIONALSupervised exercise therapy
NCT06055036Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health InterventionRECRUITINGINTERVENTIONALBlack Impact Intervention
NCT05796739SMart Angioplasty Research Team-Pragmatic Randomized Trial for Comparing Routine Versus As-Needed EXercise or Pharmacologic Stress Testing in Asymptomatic Patients With High-Risk Coronary CalciuM (SMART-EXAM)RECRUITINGINTERVENTIONALNon-invasive stress test, Medical treatment without further testing
NCT05906056Program of Continuous Passive Motion Exercises Against Heterotopic OssificationRECRUITINGINTERVENTIONALContinuous Passive Motion (CPM), Conventional physiotherapy (PT), Zoledronic Acid Injection
NCT05436600Asymptomatic Carotid Stenosis and Mobility Function With Exercise InterventionRECRUITINGINTERVENTIONALExercise Intervention
NCT04945174Stroke School - Cross-sectorial Physical Exercise for Patients With Minor Stroke or Non-disabling StrokeRECRUITINGINTERVENTIONALCardiorespiratory exercise combined with patient education and individual follow-up sessions
NCT05252208Is Stretching Superior to Aerobic Training for Reducing Blood Pressure?RECRUITINGINTERVENTIONALStretching exercise, Walking exercise
NCT04800276Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease (ACTIV'AO)RECRUITINGINTERVENTIONALmuscle strengthening targeted on ischemic areas, global muscle strenghtening
NCT07586150Personalised Pharmaco-Lifestyle Interventions for Severe Mental Illnesses Enhanced by Digital Health and Immersive TechnologiesNOT YET RECRUITINGINTERVENTIONALSemaglutide (SEMA), Exercise module, Anti-inflammatory diet module
NCT06369350Effects of Vitamin B6 on the Exercise Pressor Reflex in Lower Limb Ischemia-ReperfusionNOT YET RECRUITINGINTERVENTIONALVitamin B6 25 MG, Vitamin B6 50 MG, Vitamin B6 100 MG
NCT07550959Evaluation of the Effectiveness of Hybrid Cardiac Rehabilitation in Peripheral Artery DiseaseNOT YET RECRUITINGINTERVENTIONALHybrid Cardiac Rehabilitation, Supervised Exercise Therapy
NCT07640360WATCH-STEP : Pilot Trial: Smartwatch-Guided Secondary Prevention After Stroke Randomized Trial of Nurse-led Program With Active vs Passive Smartwatch in Minor Stroke. A Randomized Controlled Trial Evaluating a Nurse-led Secondary Prevention and Physical Activity Program Supported by Either an Active Smartwatch (Structured Feedback) or Passive Smartwatch in Patients With Minor Stroke.NOT YET RECRUITINGINTERVENTIONALSmartwatch-Guided Secondary Prevention after Stroke
NCT07609290Effects of Exercise Snacks on Clinical and Health Outcomes in Sedentary Populations With Chronic DiseasesNOT YET RECRUITINGINTERVENTIONALExercise Snacks
NCT07573995Feasibility and Effects of Inspiratory Muscle Training Combined With Blood Flow Restriction for Frail Older Adults: A Pilot Randomized Controlled TrialNOT YET RECRUITINGINTERVENTIONALExercise, Sham Control
NCT07482943The Effect of Dapagliflozin on Exercise and Cardiac Functional Status of Patients After Fontan ProcedureNOT YET RECRUITINGINTERVENTIONALDapagliflozin (5-10 mg daily) - SGLT2 Inhibitor Therapy
NCT07319611Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With LipedemaNOT YET RECRUITINGINTERVENTIONALIntermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
NCT07255677Effect of Stretching Exercises Versus Aerobic Exercises on PreeclampsiaNOT YET RECRUITINGINTERVENTIONALStretching exercises program, Aerobic exercises program, Antihypertensive drugs
NCT07309068Acute Effects of Blood Flow Restriction Training on Balance and Proprioception: A Randomized Controlled Blinded StudyAcute BFR Training Effects on Balance and ProprioceptionCOMPLETEDINTERVENTIONALBFR, sham BFR, Proprioceptive Exercise Training
NCT07209527Evaluation of Truway Health-Sourced Portable Diagnostic Devices for Early Detection of Chronic Conditions in Outpatient Primary Care Settings: A Prospective Interventional StudyENROLLING BY INVITATIONINTERVENTIONALTruway Portable Ultrasound Device, Truway Blood Glucose Monitor, Standard Oral Hypoglycemic Agent
NCT07283237Enhancing Medial Knee Pain Rehabilitation : A Clinical Trial On The Effectiveness Of Blood Flow Restriction In Combination With Targeted Exercises For Adult With Varus DeformityACTIVE NOT RECRUITINGINTERVENTIONALTargeted Exercise Program, Blood Flow Restriction (BFR) Training with Targeted Exercise Program
NCT07117500Research on the Development and Implementation of an Exercise Rehabilitation Program for Aortic Dissection Patients After Percutaneous Intervention Based on the Behavior Change Wheel TheoryENROLLING BY INVITATIONINTERVENTIONALRoutine, BCW
NCT06979830The Effects of Yoga Exercises on Body Composition, Respiratory Parameters and Functional Levels in Overweight and Obese Women: A Randomized Controlled TrialNOT YET RECRUITINGINTERVENTIONALyoga exercises
NCT06852560GEM: A Single-Arm Trial Assessing Feasibility of Allostatic Load Biomarkers and CVD Risk Among Black Breast Cancer SurvivorsWITHDRAWNINTERVENTIONALGratitude, exercise, and mindfulness program
NCT06967714Disentangling the Variability of Exercise-induced Hypoalgesia: the Role of Circulatory CompoundsCOMPLETEDINTERVENTIONALExercise
NCT06828172Local or Systemic Vascular Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PADENROLLING BY INVITATIONINTERVENTIONALExercise
NCT06830967Virtual Prehabilitation for Patients Undergoing Abdominal Aortic Aneurysm RepairNOT YET RECRUITINGINTERVENTIONALPrehabilitation, Exercise therapy, Smoking cessation counselling
NCT06827171Impact of Low-level Laser and Aerobic Exercise on Peripheral Arterial Outcomes in Patients With Type 2 DiabetesCOMPLETEDINTERVENTIONALaerobic exercise + low-level laser therapy, Aerobic exercise
NCT05885074Mechanistic Insights to Weight Loss Maintenance Through SGLT2 InhibitorsWITHDRAWNINTERVENTIONALEmpagliflozin Arm, Control Arm, Exercise capacity VO2 maximum determination
NCT06780891Telephysical Therapy as a Secondary Stroke Prevention ToolCOMPLETEDINTERVENTIONALTelephysical therapy, Educational session
NCT07117643Influence of Remote Ischemic Preconditioning Reperfusion/Reocclusion Training and Physical Exercises on the Inflammatory, Angiogenic, Neurotrophic and Anti-tumor Potential of Human Serum in Vivio/in Vitro Studies - Role of Vitamin d and Iron MetabolismENROLLING BY INVITATIONINTERVENTIONALIschemic Preconditioning
NCT06846840Effect of Ketone Esters Ingested During Recovery on Metabolism and Subsequent Exercise CapacityACTIVE NOT RECRUITINGINTERVENTIONALKetone ester, Placebo
NCT07328646EFFECTIVENESS OF A BEHAVIOR CHANGE INTERVENTION AIMED AT INCREASING PHYSICAL ACTIVITY IN PATIENTS WITH PERIPHERAL ARTERY DISEASE UNDERGOING ENDOVASCULAR REVASCULARIZATIONACTIVE NOT RECRUITINGINTERVENTIONALBehavior Change-Based Physical Activity Program, Supervised Exercise Program, Combined Behavior Change and Exercise Program
NCT06615726Regular Physical Exercise in Patients With Symptomatic Intracranial Arterial Stenosis: a Prospective Randomized Open-label Blinded Endpoint TrialACTIVE NOT RECRUITINGINTERVENTIONALRegular physical exercise, Control group
NCT07367555Effect Of Sodium Glucose Co-Transporter-2 (SGLT-2) Inhibitors on Body Mass Index After 3 Months of Use in Diabetic Patients"COMPLETEDINTERVENTIONALOral 100 gram Empagliflozin tablet along with diet plan and exercise, Diet plan and exercise
NCT06476236M4C Nutraceutical Intervention Human Health Effects PilotUNKNOWNINTERVENTIONALM4C
NCT06023498Optimizing Impact of Manual Therapy and Exercise on Lumbar Spinal Stenosis With Neurogenic Claudication: A Multi-Site Feasibility StudyCOMPLETEDINTERVENTIONALManual Therapy and Exercise, Intramuscular Electroacupuncture
NCT06350487The Efficacy of Enavogliflozin on Exercise Performance and Diastolic Function in Heart Failure With Preserved Ejection Fraction: A Randomized Controlled TrialUNKNOWNINTERVENTIONALSGLT2 inhibitor
NCT06432868Effects of Solarplast (R) Supplementation on Biomarkers of Muscle Damage, Inflammation and Recovery of Physical Performance Following High-intensity Resistance ExerciseUNKNOWNINTERVENTIONALSolarplast (R), Placebo
NCT06507501Effects of Exercise Training with Blood Flow Restriction on Lower Extremity Muscle Strength, Balance, Functional and Cognitive Performance in Healthy IndividualsCOMPLETEDINTERVENTIONALLow Load Blood Flow Restriction Exercise Training (LL-BFRE), High Load Resistive Exercise Training (HL-RE)
NCT07262203Effectiveness of Diabetic Foot Exercises on Peripheral Vascular Status Among Patients With Type 2 Diabetes Mellitus: A Randomized Controlled TrialCOMPLETEDINTERVENTIONALDiabetic Foot Exercise Program
NCT06275906Influence of a Different Percentage of Nutrients on the Effects of a Low-calorie Mediterranean Diet Associated With Physical Exercise on the Parameters of Steatosis, Intestinal Function and Metabolic Risk in Patients With Obesity and NAFLDCOMPLETEDINTERVENTIONALMediterranean diet and moderate intensity physical exercise (outdoor walking).
NCT06212700Virtual Multimodal Hub for Patients Undergoing Major Gastrointestinal Cancer Surgery - PRIORITY-CONNECT 2 Pilot Randomised Type I Hybrid Effectiveness-Implementation TrialUNKNOWNINTERVENTIONALPreoperative Exercise, Postoperative Exercise, Preoperative Nutrition
NCT07230873The Impact of Stationary Combined Exercise on Adiponectin and High-Sensitivity C-Reactive Protein Levels in Overweight WomenCOMPLETEDINTERVENTIONALCombined Exercise Group, No Structured Exercise

Genetic associations (0)

None linked.