C
Plasminogen activator inhibitor-1
Hemostatic & ThromboticLab test / biomarkerriskpartially modifiable
9
evidence score
Also known as: increased expression of plasminogen activator inhibitor-1 (PAI)-1, plasminogen activator inhibitor 1, plasminogen activator inhibitor-1 (PAI-1)
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 6meta-analyses: 0trials: 3genetic: 0MR bonus:
References (3)
0 meta-analyses / systematic reviews- Adverse effects of glucocorticoids: coagulopathy. — European journal of endocrinology 2015 · PMID 25971647
- Diabetes mellitus and macrovascular disease: mechanisms and mediators. — The American journal of medicine 2007 · PMID 17826041
- Plasminogen activator system and vascular disease. — Current vascular pharmacology 2006 · PMID 16611153
Clinical trials (1)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT04305171 | Effect of Non-surgical Periodontal Treatment on Plasma Fibrinogen, Plasminogen Activator Inhibitor 1 and C-reactive Protein Levels in Cardiovascular Disease Patients With Periodontitis | COMPLETED | OBSERVATIONAL | non-surgical periodontal treatment |
Genetic associations (0)
None linked.