C
pulmonary arterial hypertension
Comorbid ConditionsDisease / conditionriskpartially modifiable
11
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 3meta-analyses: 0trials: 8.4genetic: 0MR bonus:
References (1)
0 meta-analyses / systematic reviews- Obstructive sleep apnea, oxidative stress and cardiovascular disease: lessons from animal studies. — Oxidative medicine and cellular longevity 2013 · PMID 23533685
Clinical trials (6)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT05968859 | Peripheral Limitations in Pulmonary Hypertension and Effects of Muscle Training - The PH Training Trial | ACTIVE NOT RECRUITING | INTERVENTIONAL | Aerobic Training, Leg Training |
| NCT04316143 | An Open-label, Multicentre Study to Evaluate Pharmacokinetics, Safety and Efficacy of Zamicastat as Adjunctive Therapy in Pulmonary Arterial Hypertension (PAH) | COMPLETED | INTERVENTIONAL | Oral zamicastat |
| NCT00303459 | Effects of Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Morbidity and Mortality in Symptomatic Patients With Pulmonary Arterial Hypertension - A Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel Group, Prospective, Event Driven Phase IV Study | COMPLETED | INTERVENTIONAL | bosentan, placebo |
| NCT00080457 | A Phase 3, Randomized, Double-Blind, Placebo-Controlled Safety and Efficacy Study of Sitaxsentan Sodium (Thelin™) Treatment With an Open-Label Bosentan Arm in Patients With Pulmonary Arterial Hypertension (PAH) | COMPLETED | INTERVENTIONAL | sitaxsentan sodium |
| NCT04278404 | Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs | RECRUITING | OBSERVATIONAL | The POP02 study is collecting bodily fluid samples (i.e., whole blood, effluent samples) of children prescribed the following drugs of interest per standard of care: |
| NCT00377949 | The Natural History and Outcome of Patients With Scleroderma at High Risk for or With Early Pulmonary Hypertension | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.