B
Pulse pressure
Blood Pressure & HemodynamicsPhysical parameterriskpartially modifiable
30
evidence score
Also known as: brachial pulse pressure, large pulse pressure, peripheral pulse pressure, pulse pressure (PP)
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 18.1meta-analyses: 9.1trials: 3genetic: 0MR bonus:
References (64)
2 meta-analyses / systematic reviews- METABrachial pulse pressure and cardiovascular or all-cause mortality in the general population: a meta-analysis of prospective observational studies. — Journal of clinical hypertension (Greenwich, Conn.) 2014 · PMID 25052820
- METAJob strain and cardiovascular disease risk factors: meta-analysis of individual-participant data from 47,000 men and women. — PloS one 2013 · PMID 23840664
- Microalbuminuria Is Associated With Left Ventricular Systolic Function in Newly Diagnosed Hypertensive Patients. — Echocardiography (Mount Kisco, N.Y.) 2025 · PMID 40474762
- Determinants of hand pulse wave velocity and hand pulse transit time in healthy adults. — Scientific reports 2024 · PMID 38698185
- Implications of pulse wave velocity and central pulse pressure in heart failure with reduced ejection fraction. — Blood pressure 2024 · PMID 38819846
- Effects of low-pressure Valsalva maneuver on changes in cerebral arterial stiffness and pulse wave velocity. — PloS one 2024 · PMID 39331633
- Relationship of Arterial Stiffness and Central Hemodynamics With Cardiovascular Risk In Hypertension. — American journal of hypertension 2023 · PMID 36645322
- Blood pressure, arterial stiffness, and cardiovascular risk profiles in 8-12-year-old children following preeclampsia (FINNCARE-study). — Journal of hypertension 2023 · PMID 37337860
- Heart-Lung Interactions. — Seminars in respiratory and critical care medicine 2023 · PMID 37541314
- Central and brachial pulse pressure predicts cardiovascular and renal events in treated hypertensive patients. — Blood pressure 2022 · PMID 35438015
- Relationship Between the Progression of Coronary Artery Disease and Pulse Pressure Index: A Cross-Sectional Work. — Angiology 2022 · PMID 36052894
- Arterial Stiffness as a Cardiovascular Risk Factor After Successful Kidney Transplantation in Diabetic and Nondiabetic Patients. — Transplantation proceedings 2022 · PMID 36064673
- Carotid intima media thickness (CIMT) in adults in the AWI-Gen Nairobi site study: Profiles and predictors. — Hipertension y riesgo vascular 2022 · PMID 36153304
- Association of NT-ProBNP, Blood Pressure, and Cardiovascular Events: The ARIC Study. — Journal of the American College of Cardiology 2021 · PMID 33538254
- Effects of Moderate Combined Resistance- and Aerobic-Exercise for 12 Weeks on Body Composition, Cardiometabolic Risk Factors, Blood Pressure, Arterial Stiffness, and Physical Functions, among Obese Older Men: A Pilot Study. — International journal of environmental research and public health 2020 · PMID 33022918
- Association between estimated pulse wave velocity and the risk of stroke in middle-aged men. — International journal of stroke : official journal of the International Stroke Society 2020 · PMID 33045935
- Ambulatory pulse pressure components: concept, determination and clinical relevance. — Journal of hypertension 2019 · PMID 30817458
- Arterial stiffness as a risk factor for cardiovascular events and all‐cause mortality in people with Type 2 diabetes — Diabetic Medicine 2019 · PMID 30920676
- Cardiopulmonary Interactions: Physiologic Basis and Clinical Applications. — Annals of the American Thoracic Society 2018 · PMID 28820609
- Aortic Pulse Pressure Does Not Adequately Index Cardiovascular Risk Factor-Related Changes in Aortic Stiffness and Forward Wave Pressure. — American journal of hypertension 2018 · PMID 29684105
- Arterial Flow, Pulse Pressure and Pulse Wave Velocity in Men and Women at Various Ages. — Advances in experimental medicine and biology 2018 · PMID 30051383
- Basic concepts of heart-lung interactions during mechanical ventilation. — Swiss medical weekly 2017 · PMID 28944931
- Pulse pressure amplification and its determinants. — Blood pressure 2016 · PMID 26414776
- The conundrum of arterial stiffness, elevated blood pressure, and aging. — Current hypertension reports 2015 · PMID 25687599
- Pulse Pressure Amplification and Arterial Stiffness in Low-Risk, Uncomplicated Pregnancies. — Angiology 2015 · PMID 26251051
- Lifelong Cyclic Mechanical Strain Promotes Large Elastic Artery Stiffening: Increased Pulse Pressure and Old Age-Related Organ Failure. — The Canadian journal of cardiology 2015 · PMID 26961664
- Arterial stiffness as a risk factor for coronary artery disease. — Current atherosclerosis reports 2014 · PMID 24402301
- Central hemodynamics are associated with cardiovascular disease and albuminuria in type 1 diabetes. — American journal of hypertension 2014 · PMID 24627444
- Arterial Stiffness and Hypertension — Hypertension 2014 · PMID 24752432
- Brachial vs. central systolic pressure and pulse wave transmission indicators: a critical analysis. — American journal of hypertension 2014 · PMID 25233859
- Combined exposure to lead, inorganic mercury and methylmercury shows deviation from additivity for cardiovascular toxicity in rats. — Journal of applied toxicology : JAT 2014 · PMID 25523840
- Pulse wave velocity, pulse pressure and number of carotid or femoral plaques improve prediction of cardiovascular death in a population at low risk. — Journal of human hypertension 2013 · PMID 23426066
- Does it make sense to measure only the brachial blood pressure? — Blood purification 2013 · PMID 23735431
- Pulse pressure amplification, pressure waveform calibration and clinical applications. — Atherosclerosis 2012 · PMID 22832004
- Role of arterial stiffness in cardiovascular disease — JRSM Cardiovascular Disease 2012 · PMID 24175067
- Distribution of ankle—brachial index and the risk factors of peripheral artery disease in a multi-ethnic Asian population — Vascular Medicine 2011 · PMID 21447605
- Arterial stiffness, pulse pressure, and cardiovascular disease-is it possible to break the vicious circle? — Atherosclerosis 2011 · PMID 21621778
- Arterial stiffness, central hemodynamics, and cardiovascular risk in hypertension — Vascular Health and Risk Management 2011 · PMID 22174583
- Arterial Stiffness and Cardiovascular Events — Circulation 2010 · PMID 20083680
- Pulse pressure amplification a mechanical biomarker of cardiovascular risk. — Journal of the American College of Cardiology 2010 · PMID 20202520
- Aging and Arterial Stiffness — Circulation Journal 2010 · PMID 20962429
- Central blood pressure and hypertension: role in cardiovascular risk assessment. — Clinical science (London, England : 1979) 2009 · PMID 19138169
- Pulse pressure in youth and carotid intima-media thickness in adulthood: the cardiovascular risk in young Finns study. — Stroke 2009 · PMID 19265060
- Pulse pressure and cardiovascular autonomic neuropathy according to duration of type 1 diabetes. — Diabetes/metabolism research and reviews 2009 · PMID 19437445
- Arterial stiffness in mild-to-moderate CKD. — Journal of the American Society of Nephrology : JASN 2009 · PMID 19608701
- Arterial blood pressure measurement and pulse wave analysis--their role in enhancing cardiovascular assessment. — Physiological measurement 2009 · PMID 19940350
- Arterial stiffness and wave reflection: Biomarkers of cardiovascular risk — Artery Research 2009 · PMID 20161241
- Brachial arterial pressure to assess cardiovascular structural damage: an overview and lessons from clinical trials. — Journal of nephrology 2008 · PMID 18264933
- Pulse pressure amplification and risk of cardiovascular disease. — American journal of hypertension 2008 · PMID 18369358
- Noninvasive assessment of arterial pressure. — Current opinion in critical care 2008 · PMID 18467893
- Pulse pressure, arterial stiffness and wave reflections (augmentation index) as cardiovascular risk factors in hypertension. — Therapeutic advances in cardiovascular disease 2008 · PMID 19124404
- Cardiovascular risk factors, atherosclerosis and pulse pressure. — Advances in cardiology 2007 · PMID 17075210
- Arterial stiffness: clinical relevance, measurement and treatment. — Clinical science (London, England : 1979) 2007 · PMID 17623012
- Arterial stiffness: a new surrogate end point for cardiovascular disease? — Journal of Nephrology 2007 · PMID 18050143
- Ambulatory Arterial Stiffness Index as a Predictor of Cardiovascular Mortality in the Dublin Outcome Study — Hypertension 2006 · PMID 16432047
- Arterial Stiffness and Risk of Coronary Heart Disease and Stroke — Circulation 2006 · PMID 16461838
- Prognostic Value of Aortic Pulse Wave Velocity as Index of Arterial Stiffness in the General Population — Circulation 2006 · PMID 16461839
- Hypertension in older people: part 1. — Journal of clinical hypertension (Greenwich, Conn.) 2006 · PMID 16760685
- Pulse wave analysis and pulse wave velocity: a review of blood pressure interpretation 100 years after Korotkov. — Circulation journal : official journal of the Japanese Circulation Society 2006 · PMID 16998252
- Clinical measurement of arterial stiffness obtained from noninvasive pressure waveforms — American Journal of Hypertension 2005 · PMID 15683725
- Vascular development, pulse pressure, and the mechanisms of hypertension. — Hypertension (Dallas, Tex. : 1979) 2005 · PMID 15911744
- Cross-Sectional Relations of Peripheral Microvascular Function, Cardiovascular Disease Risk Factors, and Aortic Stiffness — Circulation 2005 · PMID 16330686
- C-Reactive Protein Is Associated With Arterial Stiffness in Apparently Healthy Individuals — Arteriosclerosis Thrombosis and Vascular Biology 2004 · PMID 15001456
- Changes in Arterial Stiffness and Wave Reflection With Advancing Age in Healthy Men and Women — Hypertension 2004 · PMID 15123572
Clinical trials (1)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT03547817 | Intermittent Negative Pressure to Improve Blood Flow in Patients With Peripheral Artery Disease. An Experimental Study to Investigate the Optimal Pulse Pressure Regime to Improve Blood Flow. | COMPLETED | INTERVENTIONAL | Intermittent negative pressure device |
Genetic associations (0)
None linked.