A
Pulse wave velocity
Blood Pressure & HemodynamicsPhysical parameterriskpartially modifiable
50
evidence score
Also known as: Carotid-to-radial pulse wave velocity, arterial pulse wave velocity, central pulse wave velocity, central pulse wave velocity (cPWV), pulse wave velocity (PWV), pwv
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 22.3meta-analyses: 20trials: 7.8genetic: 0MR bonus:
References (169)
12 meta-analyses / systematic reviews- METAAccuracy of pulse wave velocity for screening coronary artery disease: a systematic review and meta-analysis. — Diagnosis (Berlin, Germany) 2025 · PMID 39814690
- METAThe effects of acute exposure to prolonged sitting, with and without interruption, on central and peripheral pulse wave velocity: A systematic review and meta-analysis. — Vascular medicine (London, England) 2025 · PMID 40528700
- METAEffects of Periodontal Therapy on Cardiovascular Risk Biomarkers: A Systematic Review. — Oral health & preventive dentistry 2025 · PMID 40842443
- METAPsoriasis treatments in the stabilization of atherosclerosis: a systematic review. — Archives of dermatological research 2024 · PMID 39739136
- METAArterial Stiffness and Adult Onset Vasculitis: A Systematic Review. — Frontiers in medicine 2022 · PMID 35646970
- METAShift Work and Early Arterial Stiffness: A Systematic Review. — International journal of environmental research and public health 2022 · PMID 36361448
- METACardiovascular Responses to Muscle Stretching: A Systematic Review and Meta-analysis. — International journal of sports medicine 2021 · PMID 33440445
- METAPreclinical markers of atherosclerosis in acromegaly: a systematic review and meta-analysis. — Pituitary 2018 · PMID 30225826
- METABrachial-Ankle Pulse Wave Velocity and the Risk Prediction of Cardiovascular Disease: An Individual Participant Data Meta-Analysis. — Hypertension (Dallas, Tex. : 1979) 2017 · PMID 28438905
- METACarotid-Femoral Pulse Wave Velocity in the Prediction of Cardiovascular Events and Mortality: An Updated Systematic Review and Meta-Analysis. — Angiology 2017 · PMID 29172654
- METASubclinical Atherosclerosis in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis. — Angiology 2016 · PMID 27252243
- METAAssociation of Subjective and Objective Sleep Duration as well as Sleep Quality with Non-Invasive Markers of Sub-Clinical Cardiovascular Disease (CVD): A Systematic Review — Journal of Atherosclerosis and Thrombosis 2016 · PMID 27840384
- Associations between heavy metal exposure and vascular age: a large cross-sectional study. — Journal of translational medicine 2025 · PMID 39754096
- The association between estimated pulse wave velocity and cardio-cerebrovascular disease risk: a cohort study. — European journal of medical research 2025 · PMID 39780263
- Comparative Effects of Different Exercise Types on Cardiovascular Health and Executive Function in Sedentary Young Individuals. — Medicine and science in sports and exercise 2025 · PMID 39780353
- The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker. — Cardiovascular diabetology 2025 · PMID 39920683
- The cardiovascular consequences of chronic sleep fragmentation: Evidence from experimental models of obstructive sleep apnea. — Sleep medicine 2025 · PMID 40398206
- Growth-differentiation factor 15 (GDF-15) is associated with arterial stiffness and impaired endothelial function with mediation by albuminuria in the Singapore study of macroangiopathy and microvascular reactivity in type 2 diabetes (SMART2D) cohort. — Endocrine 2025 · PMID 40481928
- Association between pulse wave velocity and coronary atherosclerosis. — Coronary artery disease 2025 · PMID 40546041
- Arterial Stiffness and Cardiovascular Risk Reclassification in Patients with Autoimmune Rheumatic Diseases. — High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension 2025 · PMID 40668329
- Estimated pulse wave velocity and the risk of acute kidney injury in patients undergoing coronary revascularization: a retrospective cohort study from MIMIC-IV. — Renal failure 2025 · PMID 40731387
- Exercise-induced brachial-ankle pulse wave velocity changes before and after transcatheter aortic valve replacement. — Heart and vessels 2025 · PMID 40824385
- Exploring pulse wave velocity as a vascular hemodynamic stress marker: more than just arterial stiffening? — American journal of physiology. Heart and circulatory physiology 2025 · PMID 41364544
- Integrating Vascular Aging and Genetic Risk: The Combined Impact of Estimated Pulse Wave Velocity and Genetic Predisposition on Coronary Artery Disease. — Journal of the American Heart Association 2025 · PMID 41368830
- Arterial stiffness tested by pulse wave velocity and augmentation index for cardiovascular risk stratification in antiphospholipid syndrome. — Rheumatology (Oxford, England) 2024 · PMID 37294733
- Cardiovascular Manifestations in Inflammatory Bowel Disease. — Current cardiology reviews 2024 · PMID 38018203
- Arterial Pulse Wave Velocity Signal Reconstruction Using Low Sampling Rates. — Biosensors 2024 · PMID 38392011
- Estimated pulse wave velocity and risk of new-onset heart failure. — ESC heart failure 2024 · PMID 38597255
- Determinants of hand pulse wave velocity and hand pulse transit time in healthy adults. — Scientific reports 2024 · PMID 38698185
- Flexural pulse wave velocity in blood vessels. — The Journal of the Acoustical Society of America 2024 · PMID 38717204
- Implications of pulse wave velocity and central pulse pressure in heart failure with reduced ejection fraction. — Blood pressure 2024 · PMID 38819846
- Arterial stiffness and cardiovascular risk in patients with nephrolithiasis: a 10-year prospective study. — Journal of hypertension 2024 · PMID 38934190
- Machine Learning-Assisted Analysis of Sublingual Microcirculatory Dysfunction for Early Cardiovascular Risk Evaluation and Cardiovascular-Kidney-Metabolic Syndrome Stage in Patients With Type 2 Diabetes Mellitus. — Diabetes/metabolism research and reviews 2024 · PMID 39081178
- Characteristics of pulse wave velocity and its correlation with cardiovascular disease risk factors in healthy individuals. — Kardiologia polska 2024 · PMID 39177313
- Effects of low-pressure Valsalva maneuver on changes in cerebral arterial stiffness and pulse wave velocity. — PloS one 2024 · PMID 39331633
- Reference equations for pulse wave velocity, augmentation index, amplitude of forward and backward wave in a European general adult population. — Scientific reports 2024 · PMID 39367200
- Aortic-Femoral Stiffness Gradient and Cardiovascular Risk in Older Adults. — Hypertension (Dallas, Tex. : 1979) 2024 · PMID 39371003
- Associations Between Atherosclerosis and Subsequent Cognitive Decline: A Prospective Cohort Study. — Journal of the American Heart Association 2024 · PMID 39494555
- Is There a Role for Imaging Youth at Risk of Atherosclerosis? — Current atherosclerosis reports 2023 · PMID 36848015
- Markers of arterial stiffness and urinary metabolomics in young adults with early cardiovascular risk: the African-PREDICT study. — Metabolomics : Official journal of the Metabolomic Society 2023 · PMID 36988718
- Paradoxical Associations of Occupational and Nonoccupational Sedentary Behavior With Cardiovascular Disease Risk Measures in Desk Workers. — Journal of occupational and environmental medicine 2023 · PMID 37130827
- A Critical Review on Vasoactive Nutrients for the Management of Endothelial Dysfunction and Arterial Stiffness in Individuals under Cardiovascular Risk. — Nutrients 2023 · PMID 37299579
- Blood pressure, arterial stiffness, and cardiovascular risk profiles in 8-12-year-old children following preeclampsia (FINNCARE-study). — Journal of hypertension 2023 · PMID 37337860
- Ventricular-arterial coupling and cardiovascular risk among young adults: The African-PREDICT study. — American journal of physiology. Heart and circulatory physiology 2023 · PMID 37389948
- Lifelong Heterogeneous Contribution of Cardiovascular Risk Factors to Slow and Fast Progression of Arterial Stiffness. — Hypertension (Dallas, Tex. : 1979) 2023 · PMID 37551598
- Arterial Stiffness and its Impact on Cardiovascular Health. — Current cardiology reports 2023 · PMID 37676581
- Subclinical Primary Aldosteronism and Cardiovascular Health: A Population-Based Cohort Study. — Circulation 2023 · PMID 38031887
- Update on the Use of Pulse Wave Velocity to Measure Age-Related Vascular Changes. — Current hypertension reports 2023 · PMID 38159167
- Arterial Stiffness as a Cardiovascular Risk Factor for the Development of Preeclampsia and Pharmacopreventive Options. — Current vascular pharmacology 2022 · PMID 34615450
- Augmentation index and pulse wave velocity in normotensive versus preeclamptic pregnancies: a prospective case-control study using a new oscillometric method. — Annals of medicine 2022 · PMID 34935572
- Usefulness of estimated pulse wave velocity for identifying prevalent coronary heart disease: findings from a general Chinese population. — BMC cardiovascular disorders 2022 · PMID 35016632
- Serum Level of Lactate Dehydrogenase is Associated with Cardiovascular Disease Risk as Determined by the Framingham Risk Score and Arterial Stiffness in a Health-Examined Population in China — International Journal of General Medicine 2022 · PMID 35018110
- Incremental value of the measures of arterial stiffness in cardiovascular risk assessment. — Reviews in cardiovascular medicine 2022 · PMID 35092198
- Association of ankle-brachial index with cognitive decline in patients with lacunar infarction. — PloS one 2022 · PMID 35120183
- Arterial Stiffness and Long-Term Risk of Health Outcomes: The Framingham Heart Study. — Hypertension (Dallas, Tex. : 1979) 2022 · PMID 35168368
- Differential Roles of Life-Course Cumulative Burden of Cardiovascular Risk Factors in Arterial Stiffness and Thickness. — The Canadian journal of cardiology 2022 · PMID 35314334
- Estimated Pulse Wave Velocity Is Associated With All-Cause Mortality During 8.5 Years Follow-up in Patients Undergoing Elective Coronary Angiography. — Journal of the American Heart Association 2022 · PMID 35535599
- Global Aortic Pulse Wave Velocity is Unchanged in Bicuspid Aortopathy With Normal Valve Function but Elevated in Patients With Aortic Valve Stenosis: Insights From a 4D Flow MRI Study of 597 Subjects. — Journal of magnetic resonance imaging : JMRI 2022 · PMID 35633284
- Arterial stiffness in patients with type 1 diabetes and its comparison to cardiovascular risk evaluation tools. — Cardiovascular diabetology 2022 · PMID 35681143
- Prediction of all-cause and cardiovascular mortality using ankle-brachial index and brachial-ankle pulse wave velocity in patients with type 2 diabetes. — Scientific reports 2022 · PMID 35773381
- Cardio-ankle vascular index is more closely associated than brachial-ankle pulse wave velocity with arterial damage and risk of cardiovascular disease in patients with diabetes. — BMC cardiovascular disorders 2022 · PMID 35945498
- Arterial stiffness, endothelial dysfunction and impaired fibrinolysis are pathogenic mechanisms contributing to cardiovascular risk in ANCA-associated vasculitis. — Kidney international 2022 · PMID 35998848
- Arterial Stiffness as a Cardiovascular Risk Factor After Successful Kidney Transplantation in Diabetic and Nondiabetic Patients. — Transplantation proceedings 2022 · PMID 36064673
- Blood Pressure Responses During Exercise: Physiological Correlates and Clinical Implications. — Arteriosclerosis, thrombosis, and vascular biology 2022 · PMID 36384270
- Cardiovascular consequences of aircraft noise exposure. — Frontiers in public health 2022 · PMID 36530719
- Diabetes Mellitus, Arterial Stiffness and Cardiovascular Disease: Clinical Implications and the Influence of SGLT2i. — Current vascular pharmacology 2021 · PMID 32183678
- Triglyceride Glucose Index Is Associated With Arterial Stiffness and 10-Year Cardiovascular Disease Risk in a Chinese Population — Frontiers in Cardiovascular Medicine 2021 · PMID 33816569
- Diet quality trajectories and cardiovascular phenotypes/metabolic syndrome risk by 11-12 years. — International journal of obesity (2005) 2021 · PMID 33824404
- Arterial stiffness, the hidden face of cardiovascular risk in autoimmune and chronic inflammatory rheumatic diseases. — Autoimmunity reviews 2021 · PMID 34229047
- SPARTE Study: Normalization of Arterial Stiffness and Cardiovascular Events in Patients With Hypertension at Medium to Very High Risk — Hypertension 2021 · PMID 34455813
- Ambulatory monitoring of central arterial pressure, wave reflections, and arterial stiffness in patients at cardiovascular risk. — Journal of human hypertension 2021 · PMID 34518619
- Pulse Wave Velocity, Central Haemodynamic Parameters, and Markers of Kidney Function in Children. — Kidney & blood pressure research 2021 · PMID 34657030
- Association between combat-related traumatic injury and cardiovascular risk. — Heart (British Cardiac Society) 2021 · PMID 34824088
- [Atherosclerosis and cardiovascular risk in patients with inflammatory bowel disease]. — Terapevticheskii arkhiv 2021 · PMID 36286684
- Arterial Stiffness and Coronary Ischemia: New Aspects and Paradigms. — Current hypertension reports 2020 · PMID 31925555
- Comprehensive assessment of coronary pulse wave velocity in anesthetized pigs. — Physiological reports 2020 · PMID 32400103
- Determinants of Brachial-Ankle Pulse Wave Velocity and Vascular Aging in Healthy Older Subjects. — Medical science monitor : international medical journal of experimental and clinical research 2020 · PMID 32445331
- Establishing normal reference value of carotid ultrafast pulse wave velocity and evaluating changes on coronary slow flow. — The international journal of cardiovascular imaging 2020 · PMID 32506285
- Ambulatory arterial stiffness index in diabetic patients. — Revista medica de Chile 2020 · PMID 32730458
- Uric Acid and Vascular Damage in Essential Hypertension: Role of Insulin Resistance. — Nutrients 2020 · PMID 32825165
- Arterial Stiffness Preceding Diabetes — Circulation Research 2020 · PMID 32985370
- Effects of Moderate Combined Resistance- and Aerobic-Exercise for 12 Weeks on Body Composition, Cardiometabolic Risk Factors, Blood Pressure, Arterial Stiffness, and Physical Functions, among Obese Older Men: A Pilot Study. — International journal of environmental research and public health 2020 · PMID 33022918
- Association between estimated pulse wave velocity and the risk of stroke in middle-aged men. — International journal of stroke : official journal of the International Stroke Society 2020 · PMID 33045935
- The role of ventricular-arterial coupling in cardiac disease and heart failure: assessment, clinical implications and therapeutic interventions. A consensus document of the European Society of Cardiology Working Group on Aorta & Peripheral Vascular Diseases, European Association of Cardiovascular Imaging, and Heart Failure Association. — European journal of heart failure 2019 · PMID 30859669
- Current assessment of pulse wave velocity: comprehensive review of validation studies. — Journal of hypertension 2019 · PMID 30882597
- Arterial stiffness and cardiovascular risk — The Korean Journal of Internal Medicine 2019 · PMID 31048659
- Pulse wave velocity can be accurately measured during transcatheter aortic valve implantation and used for post-procedure risk stratification. — Journal of hypertension 2019 · PMID 31157743
- Association between triglyceride glucose index and arterial stiffness in Korean adults — Cardiovascular Diabetology 2018 · PMID 29562908
- Associations between normal range albuminuria, renal function and cardiovascular function in a population-based imaging study. — Atherosclerosis 2018 · PMID 29579673
- Aortic Pulse Pressure Does Not Adequately Index Cardiovascular Risk Factor-Related Changes in Aortic Stiffness and Forward Wave Pressure. — American journal of hypertension 2018 · PMID 29684105
- Arterial Stiffness in CKD: A Review. — American journal of kidney diseases : the official journal of the National Kidney Foundation 2018 · PMID 29908694
- Endothelial Dysfunction, Increased Arterial Stiffness, and Cardiovascular Risk Prediction in Patients With Coronary Artery Disease: FMD‐J (Flow‐Mediated Dilation Japan) Study A — Journal of the American Heart Association 2018 · PMID 30005558
- Arterial Flow, Pulse Pressure and Pulse Wave Velocity in Men and Women at Various Ages. — Advances in experimental medicine and biology 2018 · PMID 30051383
- Prognostic Cardiovascular Markers in Chronic Kidney Disease. — Kidney & blood pressure research 2018 · PMID 30153666
- Brachial-ankle pulse wave velocity, cardio-ankle vascular index, and prognosis. — Vascular health and risk management 2018 · PMID 30498357
- Submaximal exercise blood pressure and cardiovascular structure in adolescence. — International journal of cardiology 2018 · PMID 30509371
- Aortic pulse wave velocity in individuals of Asian and African ancestry: the HELISUR study. — Journal of human hypertension 2018 · PMID 30568290
- Development of Coronary Pulse Wave Velocity: New Pathophysiological Insight Into Coronary Artery Disease. — Journal of the American Heart Association 2017 · PMID 28154161
- Aortic–Brachial Arterial Stiffness Gradient and Cardiovascular Risk in the Community — Hypertension 2017 · PMID 28396534
- Sedentary Behavior and Arterial Stiffness in Adults with and without Metabolic Syndrome. — International journal of sports medicine 2017 · PMID 28486735
Clinical trials (5)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT05109949 | Acute Effect of Empagliflozin vs Dapagliflozin vs Placebo Administration Over Pulse Wave Velocity in Patients With Type Two Diabetes | UNKNOWN | INTERVENTIONAL | Dapagliflozin 10Mg Tab, Empagliflozin 25 MG, Placebo |
| NCT03382106 | Smoking Cessation and Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema | COMPLETED | INTERVENTIONAL | Sildenafil 20 MG, Placebo Oral Tablet, Pulse wave velocity |
| NCT02991703 | Simplified Pulse Wave Velocity Measurement, Validation Study of the pOpmètre in Children | COMPLETED | INTERVENTIONAL | pOpmètre®, Sphygmocor |
| NCT07589374 | Correlation Between Carotid-Femoral Pulse Wave Velocity and Triglyceride-Glucose Index and Its Derived Metrics | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT05155514 | Comparison of the Relationship Between Preoperatively Measured Pulse Wave Velocity and Hemodynamic Changes During Anesthesia Induction in Hypertensive and Normotensive Patients. | COMPLETED | OBSERVATIONAL | Mobil-O-Graph PWA |
Genetic associations (0)
None linked.