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Rheumatoid arthritis

Inflammatory & ImmuneDisease / conditionrisknon modifiable
53
evidence score
PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 20.5meta-analyses: 19.3trials: 13.2genetic: 0MR bonus:

References (112)

7 meta-analyses / systematic reviews

Clinical trials (20)

NCTTitleStatusTypeInterventions
NCT06295848The Effects of 6-week Cardiac Rehabilitation Programme on Cardiovascular Disease Risk, Systolic and Diastolic Blood Pressure and Disease Activity in Hypertensive Rheumatoid Arthritis Patients : A Randomised Controlled TrialCOMPLETEDINTERVENTIONALExercise
NCT04911127Randomized, Double Blind, Placebo-Controlled Trial to Evaluate the Safety and Tolerability of Cannabidiol (CBD) in Moderate to Severe Rheumatoid ArthritisCOMPLETEDINTERVENTIONAL200mg Cannabidiol by capsules twice daily, 400mg Cannabidiol by capsules twice daily, Placebo capsules
NCT04608344A Phase 1 Study to Evaluate OATP Transporter-Mediated Drug-Drug Interactions Between Filgotinib and Statins as Probe Drugs in Healthy ParticipantsCOMPLETEDINTERVENTIONALAtorvastatin, Pravastatin, Rosuvastatin
NCT03625089The Impact of Nurse-led Programme With and Without Carotid Ultrasound on Addressing Cardiovascular Risk in Patients With Arthritis: a Prospective, Multicentre, Randomised, Controlled TrialWITHDRAWNINTERVENTIONALAtorvastatin
NCT04056039Efficacy of Atorvastatin vs Colchicine in Decrease of Troponin I of High Sensitivity as a Biomarker of Myocardial Damage in Patients With Rheumatoid Arthritis With Severe Activity.COMPLETEDINTERVENTIONALAtorvastatin, Colchicine
NCT02789800Patient-Centred Innovations for Persons With Multimorbidity - QuebecCOMPLETEDINTERVENTIONALDIMAC02
NCT02742597Patient-Centred Innovations for Persons With Multimorbidity - OntarioCOMPLETEDINTERVENTIONALTIP / IMPACT Plus Care Coordination
NCT01534871The Effects of a 12-week Cardiovascular Rehabilitation Exercise Program on Inflammatory Markers and Traditional Coronary Artery Disease Risk Factors in Patients With Rheumatoid ArthritisCOMPLETEDINTERVENTIONALExercise
NCT01389388Cholesterol Plaques in Carotid and Coronary Arteries and the Effect of Rosuvastatin in Rheumatoid Arthritis, Ankylosing Spondylitis and Other Inflammatory Joint DiseasesCOMPLETEDINTERVENTIONALRosuvastatin
NCT01548768RHYTHM (RHeumatoid Arthritis studY of THe Myocardium): How Rheumatoid Arthritis (RA) and Tumor Necrosis Factor (TNF) Inhibitors Affect the Myocardial Structure and Function.COMPLETEDINTERVENTIONALTNF inhibitors, DMARDs
NCT00554606A 54-week, Phase II, Multi-center, Open-label Extension Study to Evaluate the Efficacy, Safety and Tolerability of ACZ885 (Anti-interleukin-1B Monoclonal Antibody) in Patients With Rheumatoid ArthritisCOMPLETEDINTERVENTIONALCanakinumab
NCT00424346A 12-week, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group, Dose-finding Study to Evaluate the Efficacy, Safety and Tolerability of ACZ885 (Anti-interleukin-1beta Monoclonal Antibody) With Three Different Dose Regimens in Patients With Active Rheumatoid Arthritis Despite Stable Treatment With Methotrexate Including 76-week and 96-week ExtensionsCOMPLETEDINTERVENTIONALCanakinumab, Placebo
NCT00619905A Randomized, Double-Blind, Placebo-Controlled, Cohort Dose Escalation Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ACZ885 (Anti-Interleukin-1Beta Monoclonal Antibody) in Patients With Active Rheumatoid Arthritis (RA) Despite Ongoing Treatment With Methotrexate (MTX) 15 mg or More Weekly for at Least 3 Months.COMPLETEDINTERVENTIONALACZ885, ACZ885
NCT07315997The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) StudyRECRUITINGOBSERVATIONALhigh sensitivity cardiac troponin
NCT07363980Coronary Computed Tomography Angiography In Rheumatoid Arthritis StudyENROLLING BY INVITATIONOBSERVATIONAL
NCT04772248Safety of TofAcitinib in Routine Care Patients With Rheumatoid Arthritis (STAR-RA)- Cardiovascular EndpointsCOMPLETEDOBSERVATIONALTofacitinib, TNF Inhibitor
NCT03821090A Study in Subclinical Atherosclerosis in Patients With Rheumatoid ArthritisCOMPLETEDOBSERVATIONAL
NCT02714881Lipids, Inflammation, and Cardiovascular Risk in Rheumatoid ArthritisCOMPLETEDOBSERVATIONALCertolizumab
NCT01499732An Exploratory Trial to Evaluate Premature Endothelial Dysfunction, as Measured by Positron Emission Tomography (PET) Scan With Cold Pressor Test (CPT), in Patients With Early Rheumatoid Arthritis (RA) Compared to Patients With Established RA, and Normal Subjects. Additionally, the Relationship Between the PET Scan Findings and the Inflammatory, Cardiovascular Risk, and Endothelial Dysfunction Biomarkers Will be AnalyzedCOMPLETEDOBSERVATIONAL
NCT01105715cLDL as a Cardiovascular Disease Risk Factor in Rheumatoid ArthritisCOMPLETEDOBSERVATIONAL

Genetic associations (0)

None linked.