A
Sedentary behavior
Lifestyle & BehavioralBehavior / exposureriskmodifiable
45
evidence score
Also known as: sedentary behaviour, sedentary time, sitting time
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 17.1meta-analyses: 20trials: 7.8genetic: 0MR bonus:
References (50)
9 meta-analyses / systematic reviews- METAThe effects of acute exposure to prolonged sitting, with and without interruption, on central and peripheral pulse wave velocity: A systematic review and meta-analysis. — Vascular medicine (London, England) 2025 · PMID 40528700
- METAEffects of interventions on sedentary behaviour and cardiovascular disease biomarkers in individuals with spinal cord injury: a systematic review. — Disability and rehabilitation 2025 · PMID 41298141
- METAAssociation of sedentary time with risk of cardiovascular diseases and cardiovascular mortality: A systematic review and meta-analysis of prospective cohort studies. — Preventive medicine 2023 · PMID 38081421
- METASedentary behaviour, physical activity and psychobiological stress reactivity: A systematic review. — Biological psychology 2022 · PMID 35667480
- METABehaviour change techniques in cardiovascular disease smartphone apps to improve physical activity and sedentary behaviour: Systematic review and meta-regression. — The international journal of behavioral nutrition and physical activity 2022 · PMID 35799263
- METAEffects of Breaking Up Prolonged Sitting on Cardiovascular Parameters: A systematic Review. — International journal of sports medicine 2021 · PMID 34535019
- METAImpact of sedentary behavior on large artery structure and function in children and adolescents: a systematic review. — European journal of pediatrics 2019 · PMID 31773330
- METASedentary behavior and health outcomes: an overview of systematic reviews. — PloS one 2014 · PMID 25144686
- METASystematic review of sedentary behaviour and health indicators in school-aged children and youth. — The international journal of behavioral nutrition and physical activity 2011 · PMID 21936895
- Causal association of modifiable factors with cardiometabolic multimorbidity: an exposome-wide Mendelian randomization investigation. — Cardiovascular diabetology 2025 · PMID 40481456
- Sedentary behaviour and cardiometabolic health: Integrating the potential underlying molecular health aspects. — Metabolism: clinical and experimental 2025 · PMID 40483777
- Associations between change in moderate-to-vigorous physical activity and sedentary behaviour with risk of recurrent cardiovascular events among individuals with coronary heart disease: A prospective cohort study. — International journal of cardiology 2025 · PMID 40516657
- Physical Activity, Sedentary Behavior, and Cardiometabolic Risk Factors in People Living with HIV. — Behavioral medicine (Washington, D.C.) 2025 · PMID 40785651
- Objectively and Subjectively Measured Physical Activity and Their Associations With Cardiometabolic Risk in the UK Biobank: Retrospective Cohort Study. — JMIR mHealth and uHealth 2025 · PMID 40864886
- Sedentary behavior mediates the association between weight-adjusted waist index and cardiovascular disease in patients with diabetes. — PloS one 2025 · PMID 40920656
- Effects of shift work on sleep quality and cardiovascular function in Taiwanese police officers. — Chronobiology international 2024 · PMID 38421010
- Sedentary lifestyle, physical activity, and gastrointestinal diseases: evidence from mendelian randomization analysis. — EBioMedicine 2024 · PMID 38583262
- Lifestyle factors and their relative contributions to longitudinal progression of cardio-renal-metabolic multimorbidity: a prospective cohort study. — Cardiovascular diabetology 2024 · PMID 39026309
- Effects of Interrupting Prolonged Sitting with Light-Intensity Physical Activity on Inflammatory and Cardiometabolic Risk Markers in Young Adults with Overweight and Obesity: Secondary Outcome Analyses of the SED-ACT Randomized Controlled Crossover Trial. — Biomolecules 2024 · PMID 39199416
- Improved vascular health linked to increased physical activity levels and reduced sedentary behavior in rheumatoid arthritis. — American journal of physiology. Heart and circulatory physiology 2024 · PMID 39485295
- Do associations of physical activity and sedentary behaviour with cardiovascular disease and mortality differ across socioeconomic groups? A prospective analysis of device-measured and self-reported UK Biobank data. — British journal of sports medicine 2023 · PMID 36754587
- Paradoxical Associations of Occupational and Nonoccupational Sedentary Behavior With Cardiovascular Disease Risk Measures in Desk Workers. — Journal of occupational and environmental medicine 2023 · PMID 37130827
- Physiology of sedentary behavior. — Physiological reviews 2023 · PMID 37326297
- Maintaining brain health across the lifespan. — Neuroscience and biobehavioral reviews 2023 · PMID 37604360
- Is Sedentary Behavior a Novel Risk Factor for Cardiovascular Disease? — Current cardiology reports 2022 · PMID 35182312
- The physical activity health paradox and risk factors for cardiovascular disease: A cross-sectional compositional data analysis in the Copenhagen City Heart Study. — PloS one 2022 · PMID 35446893
- Sedentary behaviour is associated with heightened cardiovascular, inflammatory and cortisol reactivity to acute psychological stress. — Psychoneuroendocrinology 2022 · PMID 35483244
- Eveningness is associated with sedentary behavior and increased 10-year risk of cardiovascular disease: the SCAPIS pilot cohort. — Scientific reports 2022 · PMID 35581309
- Occupational risk factors for hypertension. — Journal of hypertension 2022 · PMID 35950984
- Sedentary Behaviour-A Target for the Prevention and Management of Cardiovascular Disease. — International journal of environmental research and public health 2022 · PMID 36612852
- Sleep, Sedentary Behavior, Physical Activity, and Cardiovascular Health: MESA. — Medicine and science in sports and exercise 2021 · PMID 33044436
- Hemodynamic and structural brain measures in high and low sedentary older adults. — Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2021 · PMID 33866848
- Sit less and move more for cardiovascular health: emerging insights and opportunities. — Nature reviews. Cardiology 2021 · PMID 34017139
- Physical activity and metabolic syndrome severity among older adults at cardiovascular risk: 1-Year trends. — Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 · PMID 34366176
- Nuances between sedentary behavior and physical inactivity: cardiometabolic effects and cardiovascular risk. — Revista da Associacao Medica Brasileira (1992) 2021 · PMID 34406261
- Associations between physical activity, sedentary time and cardiovascular risk factors among Dutch children. — PloS one 2021 · PMID 34449807
- Changes in Physical Activity and Sedentary Behaviour in Cardiovascular Disease Patients during the COVID-19 Lockdown. — International journal of environmental research and public health 2021 · PMID 34831684
- A Review of Obesity, Physical Activity, and Cardiovascular Disease. — Current obesity reports 2020 · PMID 32870465
- Sedentary Behavior, Exercise, and Cardiovascular Health. — Circulation research 2019 · PMID 30817262
- Sedentary lifestyle a disease from xxi century. — Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis 2019 · PMID 31221536
- A review of reviews: Sedentary behaviour and cardiovascular disease specific to older people. — International journal of older people nursing 2018 · PMID 30394684
- Is sedentary behaviour unhealthy and if so, does reducing it improve this? — International journal of clinical practice 2017 · PMID 28238228
- Sedentary Behavior and Arterial Stiffness in Adults with and without Metabolic Syndrome. — International journal of sports medicine 2017 · PMID 28486735
- Sedentary Behavior and Cardiometabolic Health Associations in Obese 11-13-Year Olds. — Childhood obesity (Print) 2017 · PMID 28574759
- Physical Activity, Sedentary Behaviours, and Cardiovascular Health: When Will Cardiorespiratory Fitness Become a Vital Sign? — The Canadian journal of cardiology 2015 · PMID 26907579
- [Sedentary behaviour and health]. — Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) 2014 · PMID 24696372
- Reallocating Time to Sleep, Sedentary Behaviors, or Active Behaviors: Associations With Cardiovascular Disease Risk Biomarkers, NHANES 2005–2006 — American Journal of Epidemiology 2013 · PMID 24318278
- Sedentary behaviour and cardiovascular disease: a review of prospective studies. — International journal of epidemiology 2012 · PMID 22634869
- Physiological and health implications of a sedentary lifestyle. — Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2010 · PMID 21164543
- Role of Low Energy Expenditure and Sitting in Obesity, Metabolic Syndrome, Type 2 Diabetes, and Cardiovascular Disease — Diabetes 2007 · PMID 17827399
Clinical trials (5)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT07609290 | Effects of Exercise Snacks on Clinical and Health Outcomes in Sedentary Populations With Chronic Diseases | NOT YET RECRUITING | INTERVENTIONAL | Exercise Snacks |
| NCT05961943 | Feasibility, Acceptability, and Outcomes of the "RESPONSE-2" Program in Reducing Sedentary Behavior in Patients With Peripheral Arterial Disease: A Mixed Methods Pilot Study | UNKNOWN | INTERVENTIONAL | RESPONSE-2-PAD |
| NCT04572737 | Personalised Activity Plan for BREAKing UP Sitting Time in Patients With Peripheral Arterial Disease and Intermittent Claudication (The BREAK UP Study) | UNKNOWN | INTERVENTIONAL | Activity plan to break up sitting time |
| NCT00853814 | Increasing Youth Physical Activity: Neighborhood Environment Influences | UNKNOWN | INTERVENTIONAL | Access to sedentary behaviors |
| NCT06869486 | Insomnia´s Impact on DNA Stability, Cardio-metabolic Health and Lifestyle Behaviors: A Case-control Study | RECRUITING | OBSERVATIONAL | Exercise, Bioelectrical Impedance, Micronucleus Assay |
Genetic associations (0)
None linked.