A
Social isolation
37
evidence score
Also known as: loneliness
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 16.7meta-analyses: 20trials: 0genetic: 0MR bonus:
References (46)
8 meta-analyses / systematic reviews- METAAssociation of social isolation, loneliness and risk of cardiovascular diseases: Meta-analysis of cohort studies. — BMC public health 2025 · PMID 40993644
- METAThe impact of social isolation and loneliness on cardiovascular disease risk factors: a systematic review, meta-analysis, and bibliometric investigation. — Scientific reports 2024 · PMID 38834606
- METASocial Isolation and Social Support Influence Health Service Utilisation and Survival after a Cardiovascular Disease Event: A Systematic Review. — International journal of environmental research and public health 2023 · PMID 36981761
- METAA systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality. — Nature human behaviour 2023 · PMID 37337095
- METASocial and Economic Factors and Malnutrition or the Risk of Malnutrition in the Elderly: A Systematic Review and Meta-Analysis of Observational Studies. — Nutrients 2020 · PMID 32168827
- METAAn overview of systematic reviews on the public health consequences of social isolation and loneliness. — Public health 2017 · PMID 28915435
- METALoneliness and social isolation as risk factors for coronary heart disease and stroke: systematic review and meta-analysis of longitudinal observational studies. — Heart (British Cardiac Society) 2016 · PMID 27091846
- METAPsychosocial interventions for patients with coronary heart disease and depression: A systematic review and meta-analysis. — European journal of cardiovascular nursing 2015 · PMID 26475227
- Plasma proteomic signatures of social isolation and loneliness associated with morbidity and mortality. — Nature human behaviour 2025 · PMID 39753750
- Association of social isolation and loneliness with incident cardiovascular diseases: results from a nationally prospective cohorts in China. — Social psychiatry and psychiatric epidemiology 2025 · PMID 40234281
- Social Isolation Is Associated With the Acceleration of Death and Incident Cardiovascular Disease in Adults With Chronic Kidney Disease. — Journal of the American Heart Association 2025 · PMID 40401602
- Synergistic effects of cardiovascular health and social isolation on adverse pregnancy outcomes. — Scientific reports 2025 · PMID 40442264
- Association of loneliness and social isolation with excess risk of cardiovascular events in people with obesity: a prospective cohort study. — Journal of global health 2025 · PMID 41039880
- Improvement of Social Isolation and Loneliness and Excess Mortality Risk in People With Obesity. — JAMA network open 2024 · PMID 38252435
- Loneliness, social isolation, and cardiovascular disease among nonveteran and Veteran women. — Journal of women & aging 2024 · PMID 38659158
- Social Isolation, Loneliness, and Cardiovascular Mortality: The Role of Health Care System Interventions. — Current cardiology reports 2024 · PMID 38713361
- Social Isolation Changes and Long-Term Outcomes Among Older Adults. — JAMA network open 2024 · PMID 39046736
- Association of cardiovascular-kidney-metabolic health and social connection with the risk of depression and anxiety. — Psychological medicine 2024 · PMID 39552398
- Social Bonds Retain Oxytocin-Mediated Brain-Liver Axis to Retard Atherosclerosis. — Circulation research 2024 · PMID 39601150
- Association of Social Isolation and Loneliness With Incident Heart Failure in a Population-Based Cohort Study. — JACC. Heart failure 2023 · PMID 36737310
- Loneliness-a clinical primer. — British medical bulletin 2023 · PMID 36752026
- The relationship between social isolation, social support, and loneliness with cardiovascular disease and shared risk factors: A narrative review. — Archives of gerontology and geriatrics 2023 · PMID 37003026
- The Role of Social Determinants of Health in Cardiovascular Diseases: An Umbrella Review. — Journal of the American Heart Association 2023 · PMID 37345825
- Joint association of loneliness and traditional risk factor control and incident cardiovascular disease in diabetes patients. — European heart journal 2023 · PMID 37385629
- Adverse Childhood Experiences, Social Isolation, Job Strain, and Cardiovascular Disease Mortality in U.S. Older Employees. — Medicina (Kaunas, Lithuania) 2023 · PMID 37512115
- Evaluation of Social Isolation, Loneliness, and Cardiovascular Disease Among Older Women in the US. — JAMA network open 2022 · PMID 35107574
- Stress and social isolation, and its relationship to cardiovascular risk in young adults with intellectual disability. — Disability and rehabilitation 2022 · PMID 35311428
- Associations of Social Isolation and Loneliness With Later Dementia. — Neurology 2022 · PMID 35676089
- Effects of Objective and Perceived Social Isolation on Cardiovascular and Brain Health: A Scientific Statement From the American Heart Association. — Journal of the American Heart Association 2022 · PMID 35924775
- Loneliness, Social Isolation, and Chronic Disease Outcomes. — Annals of behavioral medicine : a publication of the Society of Behavioral Medicine 2021 · PMID 32865550
- Loneliness and Social Isolation: Determinants of Cardiovascular Outcomes. — Current cardiology reviews 2021 · PMID 33511946
- Social isolation, social support and loneliness as predictors of cardiovascular disease incidence and mortality. — BMC geriatrics 2021 · PMID 34922471
- Social Isolation, Loneliness, and All-Cause Mortality in Patients With Cardiovascular Disease: A 10-Year Follow-up Study. — Psychosomatic medicine 2020 · PMID 31842061
- COVID-19 and the cardiovascular system: implications for risk assessment, diagnosis, and treatment options — Cardiovascular Research 2020 · PMID 32352535
- Loneliness, social isolation, cardiovascular disease and mortality: a synthesis of the literature and conceptual framework. — Journal of the Royal Society of Medicine 2020 · PMID 32407646
- Longitudinal associations between loneliness, social isolation and cardiovascular events. — Heart (British Cardiac Society) 2020 · PMID 32461329
- The role of oxidative stress in cardiovascular disease caused by social isolation and loneliness. — Redox biology 2020 · PMID 32709420
- Stress and perceived social isolation (loneliness). — Archives of gerontology and geriatrics 2019 · PMID 30825769
- Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women — Heart 2018 · PMID 29588329
- Loneliness, social isolation and risk of cardiovascular disease in the English Longitudinal Study of Ageing. — European journal of preventive cardiology 2018 · PMID 30068233
- Loneliness, Social Isolation, and Cardiovascular Health. — Antioxidants & redox signaling 2017 · PMID 28903579
- Social isolation, loneliness and health in old age: a scoping review. — Health & social care in the community 2015 · PMID 26712585
- Psychosocial risk factors for coronary heart disease. — The Medical journal of Australia 2013 · PMID 23909539
- Loneliness, social isolation, and behavioral and biological health indicators in older adults. — Health psychology : official journal of the Division of Health Psychology, American Psychological Association 2011 · PMID 21534675
- Depression, isolation, social support, and cardiovascular disease in older adults. — The Journal of cardiovascular nursing 2006 · PMID 16966925
- The risk factors for depression in first myocardial infarction patients — Psychological Medicine 2004 · PMID 15554578
Clinical trials (0)
None linked.
Genetic associations (0)
None linked.