B
Triglyceride-glucose index
33
evidence score
Also known as: tyg index
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 15.1meta-analyses: 9.1trials: 9genetic: 0MR bonus:
References (31)
2 meta-analyses / systematic reviews- METAAssociation between triglyceride glucose index and risk of cerebrovascular disease: systematic review and meta-analysis. — Cardiovascular diabetology 2022 · PMID 36324146
- METATriglyceride-glucose index and the incidence of atherosclerotic cardiovascular diseases: a meta-analysis of cohort studies. — Cardiovascular diabetology 2021 · PMID 33812373
- Inflammatory markers link triglyceride-glucose index and obesity indicators with adverse cardiovascular events in patients with hypertension: insights from three cohorts. — Cardiovascular diabetology 2025 · PMID 39780176
- Association between triglyceride-glucose (TyG) related indices and cardiovascular diseases and mortality among individuals with metabolic dysfunction-associated steatotic liver disease: a cohort study of UK Biobank. — Cardiovascular diabetology 2025 · PMID 39806394
- The synergistic effect of the triglyceride-glucose index and a body shape index on cardiovascular mortality: the construction of a novel cardiovascular risk marker. — Cardiovascular diabetology 2025 · PMID 39920683
- Association between Triglyceride-Glucose indices and ischemic stroke risk across different glucose metabolism statuses. — Diabetes research and clinical practice 2025 · PMID 40010673
- Cholesterol, high-density lipoprotein, and glucose index versus triglyceride-glucose index in predicting cardiovascular disease risk: a cohort study. — Cardiovascular diabetology 2025 · PMID 40065297
- Association between triglyceride-glucose index and subclinical carotid atherosclerosis in systemic lupus erythematosus: a cohort-based study. — Frontiers in immunology 2025 · PMID 40636109
- Associations of cumulative exposure and dynamic trajectories of the C-reactive protein-triglyceride-glucose index with incident cardiovascular disease in middle-aged and older Chinese adults: a nationwide cohort study. — Cardiovascular diabetology 2025 · PMID 40713770
- Association of C-reactive protein-triglyceride glucose index with the incidence and mortality of cardiovascular disease: a retrospective cohort study. — Cardiovascular diabetology 2025 · PMID 40750895
- Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES. — Cardiovascular diabetology 2025 · PMID 40841630
- Association of the triglyceride-glucose index combined with a body shape index with all-cause and cardiovascular mortality in individuals with cardiovascular-kidney-metabolic syndrome stage 0-3: findings from two prospective cohorts. — Cardiovascular diabetology 2025 · PMID 40988017
- The relationship between C-reactive protein-triglyceride-glucose index and cardiovascular disease: insights from the China health and retirement longitudinal study (CHARLS). — Cardiovascular diabetology 2025 · PMID 41152893
- Associations of longitudinal trajectories of triglyceride-glucose index combined with classical and novel obesity indices and cardiovascular disease: evidence from a nationwide prospective cohort study in China. — Cardiovascular diabetology 2025 · PMID 41225604
- Association between triglyceride-glucose index combined with a body shape index and atherosclerotic cardiovascular disease risk varies by glycemic status: insights from the UK Biobank. — Cardiovascular diabetology 2025 · PMID 41390803
- Environmental exposure to lead and cadmium are associated with triglyceride glucose index. — Scientific reports 2024 · PMID 38291186
- Association between triglyceride-glucose related indices with the all-cause and cause-specific mortality among the population with metabolic syndrome. — Cardiovascular diabetology 2024 · PMID 38658993
- Joint association of TyG index and high sensitivity C-reactive protein with cardiovascular disease: a national cohort study. — Cardiovascular diabetology 2024 · PMID 38715129
- The association between the triglyceride-glucose index and the risk of cardiovascular disease in US population aged ≤ 65 years with prediabetes or diabetes: a population-based study. — Cardiovascular diabetology 2024 · PMID 38741118
- Metabolic score for insulin resistance (METS-IR) predicts all-cause and cardiovascular mortality in the general population: evidence from NHANES 2001-2018. — Cardiovascular diabetology 2024 · PMID 38987779
- Comprehensive analysis of the association between triglyceride-glucose index and coronary artery disease severity across different glucose metabolism states: a large-scale cross-sectional study from an Asian cohort. — Cardiovascular diabetology 2024 · PMID 39003471
- Association of triglyceride glucose-related parameters with all-cause mortality and cardiovascular disease in NAFLD patients: NHANES 1999-2018. — Cardiovascular diabetology 2024 · PMID 39026233
- Associations of noninsulin-based insulin resistance indices with presence and extent of multiterritorial atherosclerosis: A cross-sectional study. — Journal of clinical lipidology 2024 · PMID 39537507
- Different associations of atherogenic index of plasma, triglyceride glucose index, and hemoglobin A1C levels with the risk of coronary artery calcification progression according to established diabetes. — Cardiovascular diabetology 2024 · PMID 39563338
- Triglyceride-glucose index and triglyceride to high-density lipoprotein cholesterol ratio as potential cardiovascular disease risk factors: an analysis of UK biobank data — Cardiovascular Diabetology 2023 · PMID 36797706
- Correlation of asprosin and Nrg-4 with type 2 diabetes Mellitus Complicated with Coronary Heart Disease and the Diagnostic Value. — BMC endocrine disorders 2023 · PMID 36915073
- Insulin Resistance Indices and Carotid Intima-media Thickness in Physically Fit Adults: CHIEF Atherosclerosis Study. — Endocrine, metabolic & immune disorders drug targets 2023 · PMID 36967464
- Triglyceride-glucose index as a marker in cardiovascular diseases: landscape and limitations — Cardiovascular Diabetology 2022 · PMID 35524263
- Triglyceride Glucose Index Is Associated With Arterial Stiffness and 10-Year Cardiovascular Disease Risk in a Chinese Population — Frontiers in Cardiovascular Medicine 2021 · PMID 33816569
- Elevated TyG Index Predicts Progression of Coronary Artery Calcification — Diabetes Care 2019 · PMID 31182490
- Association between triglyceride glucose index and arterial stiffness in Korean adults — Cardiovascular Diabetology 2018 · PMID 29562908
Clinical trials (7)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT07589374 | Correlation Between Carotid-Femoral Pulse Wave Velocity and Triglyceride-Glucose Index and Its Derived Metrics | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT07451860 | The Role of the Triglyceride-Glucose Index in Determining the Risk of Chronic Total Occlusion in Coronary Artery Disease | NOT YET RECRUITING | OBSERVATIONAL | triglyceride-glucose (TyG) index was calculated from routinely obtained blood samples using the formula: Triglyceride (mg/dL) × Glucose (mg/dL) / 2. |
| NCT07467161 | Impact of Vitamin D Deficiency on Insulin Resistance Assessed by Triglyceride Glucose Index in Type 2 Diabetic Patients | NOT YET RECRUITING | OBSERVATIONAL | |
| NCT07279922 | The Role of Triglyceride-glucose Index as a Predictive Marker for Insulin Resistance in Pre Diabetic Chronic Kidney Disease Patients. | NOT YET RECRUITING | OBSERVATIONAL | Triglyceride-glucose index |
| NCT07260201 | Evaluating the Triglyceride-Glucose Index and TGI-BMI for Insulin Resistance Assessment: A Comparative Study With HOMA-IR | COMPLETED | OBSERVATIONAL | |
| NCT05695651 | Association of Triglyceride Glucose Index and HOMA IR as Predictors of Vascular Complications of Type 2 Diabetes Mellitus | UNKNOWN | OBSERVATIONAL | triglyceride glucose index and HOMA IR |
| NCT07261514 | Correlation Between Triglyceride Glucose Index and Myocardial Infarct Size, Microcirculation Obstruction and Intramyocardial Hemorrhage in Patients With ST-segment Elevation Myocardial Infarction. | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.