C
Tumor necrosis factor-alpha (TNF-α)
Inflammatory & ImmuneLab test / biomarkerriskpartially modifiable
11
evidence score
Also known as: TNF-alpha, TNF-α, tumor necrosis factor (TNF)-alpha, tumor necrosis factor alpha, tumor necrosis factor-alpha (TNF-alpha)
PREVENT status
Not a PREVENT input variable.
Causal support
observational only
Score components
lit volume: 6meta-analyses: 0trials: 4.8genetic: 0MR bonus:
References (3)
0 meta-analyses / systematic reviews- Current update on HIV-associated vascular disease and endothelial dysfunction. — World journal of surgery 2007 · PMID 17372667
- Alcohol consumption, cardiovascular health, and endothelial function markers. — Alcohol (Fayetteville, N.Y.) 2007 · PMID 17980786
- Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: implication in the pathogenesis of thrombotic disorders in the elderly. — Cardiovascular research 2004 · PMID 15820196
Clinical trials (2)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT00477191 | Effects of TNF-alpha Antagonism (Etanercept) in Patients With the Metabolic Syndrome and Psoriasis | TERMINATED | INTERVENTIONAL | Etanercept |
| NCT05633290 | CharacterisatiON of carDiac funCTion in Intensive Care Unit Survivors of Sepsis (CONDUCT-ICU): A Pilot Study | UNKNOWN | OBSERVATIONAL | CMR, hs-troponin, NT-pro BNP |
Genetic associations (0)
None linked.