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Vulnerable carotid plaque

Imaging & Subclinical DiseaseImaging markerrisknon modifiable
14
evidence score

Also known as: plaque vulnerability

PREVENT status

Not a PREVENT input variable.

Causal support

trial evidence

Score components
lit volume: 3meta-analyses: 0trials: 11.1genetic: 0MR bonus:

References (1)

0 meta-analyses / systematic reviews

Clinical trials (12)

NCTTitleStatusTypeInterventions
NCT07586540Alirocumab for Stabilisation of Symptomatic Vulnerable Carotid Plaque: A Multicentre, Randomised, Double-Blind, Placebo-Controlled Trial With High-Resolution Vessel-Wall MRI and Clinical EndpointsNOT YET RECRUITINGINTERVENTIONALAlirocumab, Placebo, Atorvastatin
NCT05624658Effect of Combined Lipid-lowering Therapy on Atherosclerotic Plaque Vulnerability in Patients With Acute Coronary Syndrome, a Prospective, Open-label, Randomized, Single-center StudyUNKNOWNINTERVENTIONALCombined Lipid-lowering Therapy
NCT04470687Innovative Applications of Ultrafast Ultrasound Imaging in Peripheral Vascular Pathology: Evaluation of Carotid Plaque Vulnerability by Quantification of NeovascularizationCOMPLETEDINTERVENTIONALcontrast enhanced ultrafast ultrasound imaging
NCT03335033New Technologies to Determine Carotid Plaque Vulnerability: A Pilot Study to Assess Contrast-Enhanced Ultrasound (CEUS) and Shear Wave Elastography (SWE) in Patients With Significant Carotid PlaquesCOMPLETEDINTERVENTIONALContrast-enhanced ultrasound, Shear Wave Elastography, Ultrasound Examination
NCT03068442Amyloid Deposition and Preexisting Vulnerable Carotid Plaque Features Predicting Cognitive Improvement After SurgeryACTIVE NOT RECRUITINGINTERVENTIONALImaging with flutemetamol F 18 PET/CT
NCT0700467318F FDG and 68Ga FAPI PET/MR Imaging of Carotid Artery Plaque Vulnerability: A Clinical Study in Carotid Artery Plaque PatientsRECRUITINGOBSERVATIONAL
NCT05218421Carotid Artery Plaque Vulnerability Assessment Using Ultrafast Ultrasound TechniquesUNKNOWNOBSERVATIONALCarotid ultrasound, Biospecimen collection and examination, Blood sample collection
NCT06315153Research of Comprehensive Assessment of Carotid Plaque Vulnerability and Development of Atherosclerotic Ischemic Stroke Risk Prediction ModelUNKNOWNOBSERVATIONAL
NCT04679727Detecting the Vulnerable Carotid Plaque: "The Carotid Artery Multi-modality Imaging Prognostic (CAMP) Study" - Implications for Stroke and Cognitive Decline Prediction in Asymptomatic Carotid Artery DiseaseUNKNOWNOBSERVATIONAL
NCT04763603Assessment of Plaque Vulnerability Using a Novel Technique: Multi-spectral PhotoAcoustic Imaging.TERMINATEDOBSERVATIONAL
NCT03606330Systemic, Pancoronary and Local Plaque Vulnerability for Image-based Prediction of Acute Coronary Syndromes - the VIP StudyCOMPLETEDOBSERVATIONALCardiac imaging tests, Venous blood sample collection
NCT02124928Morphological and Serological Criteria of Plaque Vulnerability: Risk Assessment for Symptomatic and Asymptomatic Carotid Artery StenosisUNKNOWNOBSERVATIONALCarotid endarterectomy

Genetic associations (0)

None linked.