B
Weight gain
Anthropometric & Body CompositionPhysical parameterriskmodifiable
28
evidence score
PREVENT status
Not a PREVENT input variable.
Causal support
trial evidence
Score components
lit volume: 13.8meta-analyses: 6trials: 8.4genetic: 0MR bonus:
References (23)
1 meta-analyses / systematic reviews- METAShort Sleep Duration and Weight Gain: A Systematic Review — Obesity 2008 · PMID 18239586
- Exercised gut microbiota improves vascular and metabolic abnormalities in sedentary diabetic mice through gut‒vascular connection. — Journal of sport and health science 2025 · PMID 39827989
- GDF15: from biomarker to target in cancer cachexia. — Trends in cancer 2025 · PMID 40640073
- Obesity and cardiovascular health. — European journal of preventive cardiology 2024 · PMID 38243826
- A whole-food, plant-based randomized controlled trial in metastatic breast cancer: weight, cardiometabolic, and hormonal outcomes. — Breast cancer research and treatment 2024 · PMID 38446316
- Quinic acid regulated TMA/TMAO-related lipid metabolism and vascular endothelial function through gut microbiota to inhibit atherosclerotic. — Journal of translational medicine 2024 · PMID 38622667
- Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease. — Biochemical pharmacology 2023 · PMID 37926268
- Sleep, Health, and Society. — Sleep medicine clinics 2022 · PMID 35659068
- Obesity and cardiovascular disease in women. — International journal of obesity (2005) 2020 · PMID 32066824
- GDF-15 as a Weight Watcher for Diabetic and Non-Diabetic People Treated With Metformin. — Frontiers in endocrinology 2020 · PMID 33312159
- Growth differentiation factor-15 and its role in diabetes and cardiovascular disease. — Cytokine & growth factor reviews 2020 · PMID 33317942
- GDF15 mediates the effects of metformin on body weight and energy balance. — Nature 2019 · PMID 31875646
- Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars. — Diabetes care 2018 · PMID 29844096
- Healthy Weight and Obesity Prevention: JACC Health Promotion Series. — Journal of the American College of Cardiology 2018 · PMID 30236314
- Pioglitazone after Ischemic Stroke or Transient Ischemic Attack — New England Journal of Medicine 2016 · PMID 26886418
- A clinical perspective of obesity, metabolic syndrome and cardiovascular disease — JRSM Cardiovascular Disease 2016 · PMID 26998259
- Coronary heart disease risk factors in college students. — Advances in nutrition (Bethesda, Md.) 2014 · PMID 24618758
- [Sedentary behaviour and health]. — Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) 2014 · PMID 24696372
- Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice. — Arteriosclerosis, thrombosis, and vascular biology 2011 · PMID 22075248
- Shift work and cardiovascular disease - pathways from circadian stress to morbidity. — Scandinavian journal of work, environment & health 2010 · PMID 20087536
- The metabolic syndrome in children and adolescents ? an IDF consensus report — Pediatric Diabetes 2007 · PMID 17850473
- Cardiovascular metabolic syndrome – an interplay of, obesity, inflammation, diabetes and coronary heart disease — Diabetes Obesity and Metabolism 2006 · PMID 17391148
- Obstructive sleep apnea. — Annals of internal medicine 2005 · PMID 15684207
Clinical trials (6)
| NCT | Title | Status | Type | Interventions |
|---|---|---|---|---|
| NCT06640972 | A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of RDX-002 on Postprandial Triglycerides in Patients Discontinuing the Glucagon-like Peptide-1 (GLP-1) Agonists, Semaglutide, or Tirzepatide for the Treatment of Obesity | COMPLETED | INTERVENTIONAL | RDX-002, Placebo |
| NCT04623008 | Using Mental Imagination to Prevent Excessive Gestational Weight Gain in Overweight and Obese Pregnant Women | COMPLETED | INTERVENTIONAL | Goal-Oriented Episodic Future Thinking |
| NCT00878592 | Effect of Dietary and Life Style Modification on Post Liver Transplant Obesity | TERMINATED | INTERVENTIONAL | Dietary and life style modification |
| NCT00344500 | Management of Antipsychotic Medication Associated Obesity | COMPLETED | INTERVENTIONAL | Behavioral Weight Loss Program |
| NCT00686426 | Role of Dairy Products in Weight Maintenance: Prevention of Weight Regain Following Weight Loss | COMPLETED | INTERVENTIONAL | Dairy Foods, Dairy Foods |
| NCT01111812 | Prediction of Weight Gain by Children and Adolescents That Participate in a Multi-disciplinary Intervention Program for Treatment of Overweight and Obese | COMPLETED | OBSERVATIONAL |
Genetic associations (0)
None linked.